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Protein Overview: gi|914287, gi|40...

General Information:
Name(s) found: gi|914287 [NCBI NR]
gi|40549411 [NCBI NR]
gi|15990596 [NCBI NR]
Description(s) found:
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  • gi|914287|gb|AAB33493.1| astrocyte-derived trophic factor 1, ATF-1 [human, caudate, Peptide, 185 aa] [NCBI NR]
  • gi|40549411|ref|NP_954701.1| glial cell derived neurotrophic factor isoform 2 precursor [Homo sapiens] [NCBI NR]
  • gi|15990596|gb|AAL11017.1| glial cell-derived neurotrophic factor isoform [Homo sapiens] [NCBI NR]
  • Glial cell-derived neurotrophic factor isoform [hmr_yeast5_DM3-1_pombe.fasta]
  • glial cell derived neurotrophic factor isoform 2 precursor; glial cell line derived neurotrophic factor; astrocyte-derived trophic factor [HMR_022704.fasta]
  • glial cell derived neurotrophic factor isoform 2 precursor [Homo sapiens]gi|15990596|gb|AAL11017.1| glial cell-derived neurotrophic factor isoform [Homo sapiens]gi|914287|gb|AAB33493.1| astrocyte-derived trophic factor 1, ATF-1 [human, caudate, Peptide, [nrdb_11152004_Chlamydomonas]
  • glial cell derived neurotrophic factor isoform 2 precursor; astrocyte-derived trophic factor; glial cell line derived neurotrophic factor [Human2242005.fasta]
  • glial cell derived neurotrophic factor isoform 2 precursor [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 Splice Isoform 2 of Glial cell line-derived neurotrophic factor precursor [EBI-IPI_human_3.12_11-03-2005_con_reversed.fasta]
  • glial cell derived neurotrophic factor isoform 2 precursor; astrocyte-derived trophic factor; glial cell line derived neurotrophic factor [Homo sapiens] [HumanGallus06162005.fasta]
  • glial cell derived neurotrophic factor isoform 2 precursor; glial cell line derived neurotrophic factor; astrocyte-derived trophic factor [Homo sapiens] [human-NCBI-042104-rand.fasta]
  • astrocyte-derived trophic factor 1, ATF-1 [human, caudate, Peptide, 185 aa] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • glial cell-derived neurotrophic factor isoform [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 SPLICE ISOFORM 2 OF GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=GDNF Isoform 2 of Glial cell line-derived neurotrophic factor [human-ipi-250309-contam.fasta]
  • IPI:IPI00375525.3|SWISS-PROT:P39905-2|ENSEMBL:ENSP00000339703|REFSEQ:NP_954701 Tax_Id=9606 Gene_Symbol=GDNF Isoform 2 of Glial cell line-derived neurotrophic factor [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=GDNF Isoform 2 of Glial cell line-derived neurotrophic factor precursor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • glial cell line-derived neurotrophic factor isoform 2 precursor [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Isoform 2 of Glial cell line-derived neurotrophic factor OS=Homo sapiens GN=GDNF [011711_HMR.fasta]
  • GeneSymbol=GDNF Synonyms=ATF1|ATF2|HFB1-GDNF|HSCR3 glial cell line-derived neurotrophic factor isoform 2 preproprotein [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00375525.3|SWISS-PROT:P39905-2|ENSEMBL:ENSP00000339703;ENSP00000425928|REFSEQ:NP_954701|VEGA:OTTHUMP00000221304 Tax_Id=9606 Gene_Symbol=GDNF Isoform 2 of Glial cell line-derived neurotrophic factor [ipi.HUMAN.20110912.fasta]
  • Isoform 2 of Glial cell line-derived neurotrophic factor GN=GDNF [Doctor+uniprot-HUMAN-120911.fasta]
  • Isoform of P39905, Isoform 2 of Glial cell line-derived neurotrophic factor OS=Homo sapiens GN=GDNF [2016-04-human-contam-aPKC-His-Par6.fasta]
    • Organism: Homo sapiens
    Length: 185 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLWDVVAVC LVLLHTASAF PLPAANMPED YPDQFDDVMD FIQATIKRLK RSPDKQMAVL  60
   61 PRRERNRQAA AANPENSRGK GRRGQRGKNR GCVLTAIHLN VTDLGLGYET KEELIFRYCS 120
  121 GSCDAAETTY DKILKNLSRN RRLVSDKVGQ ACCRPIAFDD DLSFLDDNLV YHILRKHSAK 180
  181 RCGCI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..54] MSA 3.016972 View MSA. No confident structure predictions are available.
    2 View Details [55..185] PSI-BLAST 46.0 Glial cell-derived neurotrophic factor, GDNF

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • vascular endothelial growth factor receptor 1 binding
    		•  4.88004110368356 bayes_pls_golite062009
  • receptor serine/threonine kinase binding
    		•  4.8369569327215 bayes_pls_golite062009
  • receptor binding
    		•  4.70889547404918 bayes_pls_golite062009
  • transmembrane receptor protein serine/threonine kinase binding
    		•  4.69128752159226 bayes_pls_golite062009
  • transforming growth factor beta receptor binding
    		•  4.69128752159226 bayes_pls_golite062009
  • glial cell line-derived neurotrophic factor receptor binding
    		•  4.199474917569 bayes_pls_golite062009
  • growth factor activity
    		•  4.01406832911234 bayes_pls_golite062009
  • cytokine activity
    		•  3.61376517935324 bayes_pls_golite062009
  • vascular endothelial growth factor receptor binding
    		•  3.16494996397951 bayes_pls_golite062009
  • protein binding
    		•  3.16282476674164 bayes_pls_golite062009
  • vascular endothelial growth factor receptor 2 binding
    		•  3.0813162230094 bayes_pls_golite062009
  • type II transforming growth factor beta receptor binding
    		•  3.06631842262117 bayes_pls_golite062009
  • cell surface binding
    		•  2.9725198156666 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  2.49731836866959 bayes_pls_golite062009
  • growth factor binding
    		•  2.41942870726502 bayes_pls_golite062009
  • binding
    		•  2.37954321554411 bayes_pls_golite062009
  • heparin binding
    		•  2.11784489374422 bayes_pls_golite062009
  • hormone activity
    		•  2.10500409590202 bayes_pls_golite062009
  • platelet-derived growth factor receptor binding
    		•  1.78479767888975 bayes_pls_golite062009
  • protein dimerization activity
    		•  1.44846386076063 bayes_pls_golite062009
  • fibronectin binding
    		•  1.3732716084502 bayes_pls_golite062009
  • platelet-derived growth factor binding
    		•  1.18476084022243 bayes_pls_golite062009
  • polysaccharide binding
    		•  1.16191864095271 bayes_pls_golite062009
  • protein homodimerization activity
    		•  1.13743310822539 bayes_pls_golite062009
  • collagen binding
    		•  1.00551310632663 bayes_pls_golite062009
  • identical protein binding
    		•  1.0030262164995 bayes_pls_golite062009
  • morphogen activity
    		•  0.91146826241391 bayes_pls_golite062009
  • pattern binding
    		•  0.90497366619649 bayes_pls_golite062009
  • neurotrophin receptor binding
    		•  0.81172494974121 bayes_pls_golite062009
  • vascular endothelial growth factor receptor 3 binding
    		•  0.772832351269279 bayes_pls_golite062009
  • protein heterodimerization activity
    		•  0.408562885230686 bayes_pls_golite062009
  • transcription activator activity
    		•  0.290946570822357 bayes_pls_golite062009
  • catalytic activity
    		•  0.105223830172599 bayes_pls_golite062009
  • signal transducer activity
    		•  0.102347067903142 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.102347067903142 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.0706173408709216 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.0235054088545197 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle