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Protein Overview: ATP6V1A

General Information:
Name(s) found: ATP6V1A [HGNC (HUGO)]
Description(s) found:
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  • gi|30582183|gb|AAP35318.1| ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A, isoform 1 [Homo sapiens] [NCBI NR]
  • gi|22096378|sp|P38606.2|VATA_HUMAN RecName: Full=V-type proton ATPase catalytic subunit A; Short=V-ATPase subunit A; AltName: Full=Vacuolar proton pump subunit alpha; AltName: Full=V-ATPase 69 kDa subunit; AltName: Full=Vacuolar ATPase isoform VA68 [NCBI NR]
  • gi|19913424|ref|NP_001681.2| ATPase, H+ transporting, lysosomal V1 subunit A [Homo sapiens] [NCBI NR]
  • gi|189054542|dbj|BAG37315.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|15341906|gb|AAH13138.1| ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A [Homo sapiens] [NCBI NR]
  • gi|119600032|gb|EAW79626.1| ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A, isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119600031|gb|EAW79625.1| ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A, isoform CRA_a [Homo sapiens] [NCBI NR]
  • ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A [HGNC (HUGO)]
  • V-type proton ATPase catalytic subunit A OS=Homo sapiens GN=ATP6V1A PE=1 SV=2 [Swiss-Prot]
  • Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform (EC 3.6.3.14) (V-ATPase subunit A 1) (Vacuolar proton pump alpha subunit 1) (V-ATPase 69 kDa subunit 1) (Isoform VA68) - Homo sapiens (Human) [Swiss-Prot]
  • (P38606) Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform (EC 3.6.3.14) (V-ATPase A subunit 1) (Vacuolar proton pump alpha subunit 1) (V-ATPase 69 kDa subunit 1) (Isoform VA68) [Swiss-Prot]
  • Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform [hmr_yeast5_DM3-1_pombe.fasta]
  • ATPase, H+ transporting, lysosomal 70kD, V1 subunit A, isoform 1; V-ATPase 69 kDa subunit 1; H(+)-transporting two-sector ATPase, subunit A; vacuolar ATPase isoform VA68; ATPase, H+ transporting, lysosomal, alpha polypeptide, 70kD, isoform 1; ATPase, H+ t [HMR_022704.fasta]
  • ATPase, H+ transporting, lysosomal 70kD, V1 subunit A, isoform 1; ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A, isoform 1; H+-transporting ATPase chain A, vacuolar (VA68 type); V-ATPase A subunit 1; vacuolar proton pump alpha subunit 1; vacuolar [071204_hmrz_cont.fasta]
  • ATPase, H+ transporting, lysosomal 70kD, V1 subunit A, isoform 1 [Homo sapiens]gi|15341906|gb|AAH13138.1| ATPase, H+ transporting, lysosomal 70kD, V1 subunit A, isoform 1 [Homo sapiens]gi|30582183|gb|AAP35318.1| ATPase, H+ transporting, lysosomal 70kDa, [nrdb_11152004_Chlamydomonas]
  • Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform (V-ATPase A subunit 1) (Vacuolar proton pump alpha subunit 1) (V-ATPase 69 kDa subunit 1) (Isoform VA68) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_001690) ATPase, H+ transporting, lysosomal, subunit A1; H+-transporting ATPase chain A, vacuolar (VA68 type); vacuolar ATP synthase catalytic subunit A, ubiquitous isoform; V-ATPase A subunit 1; vacuolar proton pump alpha subunit 1; V-ATPase 69 kDa su [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • ATPase, H+ transporting, lysosomal 70kD, V1 subunit A, isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Vacuolar ATP synthase catalytic subunit A (V-ATPase subunit A) (Vacuolar proton pump subunit alpha) (V-ATPase 69 kDa subunit) (Vacuolar ATPase isoform VA68) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A, isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A, isoform 1 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 VACUOLAR ATP SYNTHASE CATALYTIC SUBUNIT A, UBIQUITOUS ISOFORM [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • ATPase, H+ transporting, lysosomal V1 subunit A [Homo sapiens] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=ATP6V1A V-type proton ATPase catalytic subunit A [human-ipi-250309-contam.fasta]
  • Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform (V-ATPase subunit A 1) (Vacuolar proton pump alpha subunit 1) (V-ATPase 69 kDa subunit 1) (Isoform VA68) [nr-271106-contam.fasta]
  • IPI:IPI00007682.2|SWISS-PROT:P38606|TREMBL:B2RBR8;B7Z1R5;B7Z2V6|ENSEMBL:ENSP00000273398|REFSEQ:NP_001681|H-INV:HIT000036145|VEGA:OTTHUMP00000172264 Tax_Id=9606 Gene_Symbol=ATP6V1A V-type proton ATPase catalytic subunit A [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=ATP6V1A Vacuolar ATP synthase catalytic subunit A ENSG00000114573 IPI00007682 [drosphohumanreversed.fasta]
  • Tax_Id=9606 Gene_Symbol=ATP6V1A Vacuolar ATP synthase catalytic subunit A [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • V-type proton ATPase catalytic subunit A [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • P38606;B2RBR8;Q53YD9;Q96DY6;Q9UHY3; RecName: Full=V-type proton ATPase catalytic subunit A; AltName: Full=Vacuolar proton pump subunit alpha; AltName: Full=V-ATPase 69 kDa subunit; AltName: Full=Vacuolar ATPase isoform VA68; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • V-type proton ATPase catalytic subunit A OS=Homo sapiens GN=ATP6V1A [011711_HMR.fasta]
  • IPI:IPI00007682.2|SWISS-PROT:P38606|TREMBL:B7Z1R5;B7Z2V6;D3DN75|ENSEMBL:ENSP00000273398|REFSEQ:NP_001681|H-INV:HIT000036145|VEGA:OTTHUMP00000172264 Tax_Id=9606 Gene_Symbol=ATP6V1A V-type proton ATPase catalytic subunit A [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=ATP6V1A Synonyms=ATP6A1|ATP6V1A1|HO68|VA68|VPP2|Vma1 V-type proton ATPase catalytic subunit A [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00007682.2|SWISS-PROT:P38606|ENSEMBL:ENSP00000273398|REFSEQ:NP_001681|H-INV:HIT000036145|VEGA:OTTHUMP00000214746 Tax_Id=9606 Gene_Symbol=ATP6V1A V-type proton ATPase catalytic subunit A [ipi.HUMAN.20110912.fasta]
  • V-type proton ATPase catalytic subunit A GN=ATP6V1A [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 617 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFSKLPKIL DEDKESTFGY VHGVSGPVVT ACDMAGAAMY ELVRVGHSEL VGEIIRLEGD  60
   61 MATIQVYEET SGVSVGDPVL RTGKPLSVEL GPGIMGAIFD GIQRPLSDIS SQTQSIYIPR 120
  121 GVNVSALSRD IKWDFTPCKN LRVGSHITGG DIYGIVSENS LIKHKIMLPP RNRGTVTYIA 180
  181 PPGNYDTSDV VLELEFEGVK EKFTMVQVWP VRQVRPVTEK LPANHPLLTG QRVLDALFPC 240
  241 VQGGTTAIPG AFGCGKTVIS QSLSKYSNSD VIIYVGCGER GNEMSEVLRD FPELTMEVDG 300
  301 KVESIMKRTA LVANTSNMPV AAREASIYTG ITLSEYFRDM GYHVSMMADS TSRWAEALRE 360
  361 ISGRLAEMPA DSGYPAYLGA RLASFYERAG RVKCLGNPER EGSVSIVGAV SPPGGDFSDP 420
  421 VTSATLGIVQ VFWGLDKKLA QRKHFPSVNW LISYSKYMRA LDEYYDKHFT EFVPLRTKAK 480
  481 EILQEEEDLA EIVQLVGKAS LAETDKITLE VAKLIKDDFL QQNGYTPYDR FCPFYKTVGM 540
  541 LSNMIAFYDM ARRAVETTAQ SDNKITWSII REHMGDILYK LSSMKFKDPL KDGEAKIKSD 600
  601 YAQLLEDMQN AFRSLED

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..617] PSI-BLAST 156.0 Crystal structure of A-type ATPase catalytic subunit A from Pyrococcus horikoshii OT3


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle