YRC Public Data Repository - Protein Structure Prediction

Protein:	ATP6V1A
Organism:	Homo sapiens
Length:	617 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ATP6V1A.

Description	E-value	Query Range	Subject Range
gi\|109033102 - gi\|109033102\|ref\|XP_001106889.1\| PREDICTED: similar to ATPase, H+ transporting, lysosomal 70kD, V1 s...	0.0	[1..617]	[1..617]
gi\|27806225, gi\|... - gi\|75775489\|gb\|AAI05146.1\| ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A [Bos taurus], gi\|2...	0.0	[1..617]	[2..618]
gi\|61369689, gi\|... - gi\|61369694\|gb\|AAX43375.1\| ATPase H+ transporting lysosomal 70kDa V1 subunit A [synthetic construct]...	0.0	[1..617]	[1..617]
VATA_PONAB - V-type proton ATPase catalytic subunit A OS=Pongo abelii GN=ATP6V1A PE=2 SV=1 VATA1_PONPY, VAT... - Vacuolar ATP synthase catalytic subunit A - Pongo pygmaeus (Orangutan), Vacuolar ATP synthase cataly...	0.0	[1..617]	[1..617]
gi\|1082432 - gi\|1082432\|pir\|\|B46091 H+-exporting ATPase (EC 3.6.3.6) chain A, vacuolar (VA68 type) - human	0.0	[1..617]	[1..617]

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Predicted Domain #1

Region A:
Residues: [1-617]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFSKLPKIL DEDKESTFGY VHGVSGPVVT ACDMAGAAMY ELVRVGHSEL VGEIIRLEGD  60
   61 MATIQVYEET SGVSVGDPVL RTGKPLSVEL GPGIMGAIFD GIQRPLSDIS SQTQSIYIPR 120
  121 GVNVSALSRD IKWDFTPCKN LRVGSHITGG DIYGIVSENS LIKHKIMLPP RNRGTVTYIA 180
  181 PPGNYDTSDV VLELEFEGVK EKFTMVQVWP VRQVRPVTEK LPANHPLLTG QRVLDALFPC 240
  241 VQGGTTAIPG AFGCGKTVIS QSLSKYSNSD VIIYVGCGER GNEMSEVLRD FPELTMEVDG 300
  301 KVESIMKRTA LVANTSNMPV AAREASIYTG ITLSEYFRDM GYHVSMMADS TSRWAEALRE 360
  361 ISGRLAEMPA DSGYPAYLGA RLASFYERAG RVKCLGNPER EGSVSIVGAV SPPGGDFSDP 420
  421 VTSATLGIVQ VFWGLDKKLA QRKHFPSVNW LISYSKYMRA LDEYYDKHFT EFVPLRTKAK 480
  481 EILQEEEDLA EIVQLVGKAS LAETDKITLE VAKLIKDDFL QQNGYTPYDR FCPFYKTVGM 540
  541 LSNMIAFYDM ARRAVETTAQ SDNKITWSII REHMGDILYK LSSMKFKDPL KDGEAKIKSD 600
  601 YAQLLEDMQN AFRSLED

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	156.0
Match:	1vdzA
Description:	Crystal structure of A-type ATPase catalytic subunit A from Pyrococcus horikoshii OT3
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits