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Protein Overview: gi|109458474

General Information:
Name(s) found: gi|109458474 [NCBI NR]
Description(s) found:
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  • gi|109458474|ref|XP_574411.2| PREDICTED: similar to ryanodine receptor 1 (skeletal) [Rattus norvegicus] [NCBI NR]
  • PREDICTED: similar to ryanodine receptor 1 (skeletal) [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 Gene_Symbol=LOC686059 similar to ryanodine receptor 1 [rat-ipi-250309-contam.fasta]
    • Organism: Rattus norvegicus
    Length: 3972 amino acids

    Gene Ontology:
    Cellular Component: membrane fraction [UNKNOWN]
    T-tubule [UNKNOWN]
    cytoplasm [UNKNOWN]
    sarcoplasmic reticulum [UNKNOWN]
    cell cortex [UNKNOWN]
    membrane [IEA]
    I band [UNKNOWN]
    plasma membrane [UNKNOWN]
    junctional membrane complex [UNKNOWN]
    sarcoplasmic reticulum membrane [UNKNOWN]
    Biological Process: response to hypoxia [UNKNOWN]
    muscle contraction [UNKNOWN]
    calcium ion transport [UNKNOWN][IEA]
    release of sequestered calcium ion into cytosol [UNKNOWN]
    Molecular Function: protein binding [UNKNOWN]
    calcium channel activity [IEA]
    voltage-gated calcium channel activity [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGDGGGEGED EVQFLRTDDE VVLQCSATVL KEQLKLCLAA EGFGNRLCFL EPTSNAQNVP  60
   61 PDLAICCFIL EQSLSVRALQ EMLANTVEAG VESSQGGGHR TLLYGHAILL RHAHSRMYLS 120
  121 CLTTSRSMTD KLAFDVGLQE DATGEACWWT MHPASKQRSE GEKVRVGDDL ILVSVSSERY 180
  181 LHLSTASGEL QVDASFMQTL WNMNPICSCC EEGFVTGGHV LRLFHGHMDE CLTISPSDSD 240
  241 DQRRLVYYEG GPVCTHARSL WRLEPLRISW SGSHLRWGQP LRIRHVTTGR YLALTEDQGL 300
  301 VVVDASKAHT KATSFCFRIS KEKLDVAPKR DVEGMGPPEI KYGESLCFVQ HVASGLWLTY 360
  361 AAPDPKALRL GVLKKKAMLH QEGHMDDALS LTRCQQEESQ AARMIYSTAG LYNQFIKGLD 420
  421 SFSGKPRGSG PPAGSALPIE GVILSLQDLI GYFEPPSEEL QHEEKQTKLR SLRNRQSLFQ 480
  481 EEGMLSLVLN CIDRLNVYTT AAHFAEFAGE EAAESWKEIV NLLYELLASL IRGNRTNCAL 540
  541 FSTNLDWLVS KLDRLEASSG ILEVLYCVLI ESPEVLNIIQ ENHIKSIISL LDKHGRNHKV 600
  601 LDVLCSLCVC NGVAVRSNQD LITENLLPGR ELLLQTNLIN YVTSIRPNIF VGRAEGSTQY 660
  661 GKWYFEVMVD EVAPFLTAQA THLRVGWALS EGYSPYPGGG EGWGGNGVGD DLYSYGFDGL 720
  721 HLWTGHVARP VTSPGQHLLG PEDVVSCCLD LSVPSISFRI NGCPVQGVFE SFNLDGLFFP 780
  781 VVSFSAGIKV RFLLGGRHGE FKFLPPPGYA PCHEAVLPRE RLHLQPIKEY RREGPRGPHL 840
  841 VGPSRCLSHL DFVPCPVDTI QIVLPPHLER IREKLAENIH ELWALTRIEQ GWTYGPVRDD 900
  901 NKRLHPCLVD FHSLPEPERN YNLQMSGETL KTLLALGCHV GMADEKAEDN LKKTKLPKTY 960
  961 MMNNGYKPAP LDLSHVRLTP AQTTLVDRLA ENGHNVWARD RVAQGWSYSA VQDIPARRNP1020
 1021 RLVPYRLLDE ATKRSNRDSL CQAVRTLLGY GYNIEPPDQE PSQVDSQSRG DRARIFRAEK1080
 1081 SYAVQSGRWD SGRQQAAGSR CGVEIGEGDF RFTDANGQRW HLGSEPFGRP WQSGDVVGCM1140
 1141 IDLTENTIIF TLNGEVLMSD SGSETAFREI EIGDGFLPVC SLGPGQVGHL NLGQDVSSLR1200
 1201 FFAICGLQEG FEPFAINMQR PVTTWFSKSL PQFEPVPLEH PHYEVARMDG TVDTPPCLRL1260
 1261 THRTWGSQNS LVEMLFLRLS LPVQFHQHFR CTAGATPLAS PGLQPPAEDE ARAAEPDTDY1320
 1321 ENLRRSAGGW GEAEAGKDGT AKEGTPGGAA QPGVEAQPAR AENEKDATTE KNKKRGFLFK1380
 1381 AKKVAMMTQP PSTPALPRLP RDVVPADNRD DPEIILNTTT YYYSVRVFAG QEPSCVWVGW1440
 1441 VTPDYHQHDM SFDLSKVRAV TVTMGDEQGN VHSSLKCSNC YMVWGGDFVS PGQQGRISHT1500
 1501 DLVIGCLVDL ATGLMTFTAN GKESNTFFQV EPNTKLFPAV FVLPTHQNVV QFELGKQKNI1560
 1561 MPLSAAMFLS ERKNPAPQCP PRLEVQMLMP VSWSRMPNHF LHVDTRRAGE RLGWAVQCQE1620
 1621 PLMMMALHIP EENSHVDQAQ LLHALEDAHL PGPLRAGYYD LLISIHLESA CRSRRSMLSE1680
 1681 YIVPLTEETR AITLFPPGRS AEDGPRRHGL PGVGVTTSLR PPHHFSPPCF VVALPAAGAA1740
 1741 EAPARLSPAI PLEALRDKAL RMLGEAVRDG GQHARDPVGG SVEFQFVPVL KLVSTLLVMG1800
 1801 VFSDEDVKQI LKMIEPEVFT EEEEMCHLLE YFCDQELQHR VESLAAFAER YVDKLQSNQR1860
 1861 GRYGLLMKAF TMSAAETARR TREFRSPPQE QINMLLQFKN GADEEDCPLP EEIREDLVNF1920
 1921 HQDLLAHCGI QLEGEEEEPE EESTLGSRLM SLLEKVRLVK KKEEKPEEEP AAEEHKPQSL1980
 1981 QELVSHTVVR WAQEDFVQSP ELVRAMFSLL HRQYDGLGEL LRALPRAYTI SLSSVEDTMS2040
 2041 LLECLGQIRS LLIVQMGPQE ENLMIQSIGN IMNNKVFYQH PNLMRALGMH ETVMEVMVNV2100
 2101 LGGGESKEIR FPKMVTSCCR FLCYFCRISR QNQRSMFDHL SYLLENSGIG LGMQGSTPLD2160
 2161 VAAASVIDNN ELALALQEQD LEKVVSYLAG CGLQSCPMLL AKGYPDIGWN PCGGERYLDF2220
 2221 LRFAVFVNGE SVEENANVVV RLLIRKPECF GPALRGEGGS GLLAAIEEAI RISEDPARDG2280
 2281 PGVRRDRRRE HFGEEPPEEN RVHLGHAIMS FYAALIDLLG RCAPEMHLIQ AGKGEALRIR2340
 2341 AILRSLVPLD DLVGIISLPL QIPTLGKDGA LVQPKMSASF VPDHKASMVL FLDRVYGIEN2400
 2401 QDFLLHVLDV GFLPDMRAAA SLDTATFSHP GDGRWHLPAT CALAVLPLIT KCAPLLRGTE2460
 2461 HRAIMVDSML HTVYRLSRGR SLTKAQRDVI EDCLMALCRY IRPSMLQHLL RRLVFDVPIL2520
 2521 NEFAKMPLKL LTNHYERCWK YYCLPTGWAN FGVTSEEELH LTRKLFWGIF DSLAHKKYDQ2580
 2581 ELYRIAMPCL CAIAGALPPD YVDASYSSKT EKKATVDAEG NFDPRPVETL NVIIPEKLDS2640
 2641 FINKFAEYAH EKWAFDKIQN NWSYGENIDE ELKTHPMLRP YKTFSEKDKE IYRWPIKESL2700
 2701 KAMIAWEWTV EKAREGEEEK TEKKKTRKIS QTAQTYDPRE GYNPQPPDLS VVTLSRELQA2760
 2761 MAEQLAENYH NTWGRKKKQE LEAKGGGSHP LLVPYDTLTA KEKARDREKA QELLKFLQMN2820
 2821 GYAVTRGLKD MELDTSSIEK RFAFGFLQQL LRWMDISQEF IAHLEAVVSS GRVEKSPHEQ2880
 2881 EIKFFAKILL PLINQYFTNH CLYFLSTPAK VLGSGGHASN KEKEMITSLF CKLAALVRHR2940
 2941 VSLFGTDAPA VVNCLHILAR SLDARTVMKS GPEIVKAGLR SFFESASEDI EKMVENLRLG3000
 3001 KVSQARTQVK GVGQNLTYTT VALLPVLTTL FQHIAQHQFG DDVILDDVQV SCYRTLCSIY3060
 3061 SLGTTRNPYV EKLRPALGEC LARLAAAMPV AFLEPELNEY NACSVYTTKS PRERAILGLP3120
 3121 NSVEEMCPDI PVLERLMAEI GGLAESGARY TEMPHVIEIT LPMLCSYLPR WWERGPEAPP3180
 3181 PALPAGAPPP CTAVTSDHLN SLLGNILRII VNNLGIDEAS WMKRLAVFAQ PIVSRARPEL3240
 3241 LRSHFIPTIG RLRKRAGKVV AEEEQLRLEA KAEAEEGELL VRDEFSVLCR DLYALYPLLI3300
 3301 RYSGGSDQER TKKKRRGDRY SVQTSLIVAT LKKMLPIGLN MCAPTDQDLI VLAKARYALV3360
 3361 LIRAHPGPYC FWDPGEPLRS NGDFQNPDVE SPKALSYPFQ FLIKSGLGGG GLRVMVEDEA3420
 3421 SRLTQWVLSS QKDTDEEVRE FLQNNLNLQG KVEGSPSLRW QMALYRGVPG REEDADDPEK3480
 3481 IVRRVQEVSA VLYHLDQTEH PYKSKKAVWH KLLSKQRRRA VVACFRMTPL YNLPTHRACN3540
 3541 MFLESYKASW ILTEDHSFED RMIDDLSKAG EQEEEEEEVE EKKPDPLHQL VLHFSRTALT3600
 3601 EKSKLDEDYL YMAYADIMAK GLLEGGRGIR FAHSPTHAAP QSCHLEEGGE NVEEGGEEEE3660
 3661 VEVSFEEKEM EKQRLLYQQS RLHNRGAAEM VLQMISACKG ETGAMVSSTL KLGISILNGG3720
 3721 NAEVQQKMLD YLKDKKEVGF FQREKVMADD EFTQDLFRFL QLLCEGHNND FQNYLRTQTG3780
 3781 NTTTINIIIC TVDYLLRLQE SISDFYWYYS GKDVIEEQGK RNFSKAMSVA KQVFNSLTEY3840
 3841 IQGPCTGNQQ SLAHSRLWDA VVGFLHVFAH MMMKLAQDSS QIELLKELLD LQKDMVVMLL3900
 3901 SLLEGNVVNG MIARQMVDML VESSSNVEMI LKFFDMFLKL KDIVGSEAFQ DYVTDPRGLI3960
 3961 SKKDFQKVGA RQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle