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Protein Overview: POLR3C

General Information:
Name(s) found: POLR3C [HGNC (HUGO)]
Description(s) found:
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  • gi|60393871|sp|Q9BUI4.1|RPC3_HUMAN RecName: Full=DNA-directed RNA polymerase III subunit RPC3; Short=RNA polymerase III subunit C3; AltName: Full=DNA-directed RNA polymerase III subunit C; AltName: Full=DNA-directed III 62 kDa polypeptide; AltName: Full=R [NCBI NR]
  • gi|21359969|ref|NP_006459.3| polymerase (RNA) III (DNA directed) polypeptide C (62kD) [Homo sapiens] [NCBI NR]
  • gi|20159753|gb|AAM12033.1| RNA polymerase III subunit RPC62 [Homo sapiens] [NCBI NR]
  • gi|12803519|gb|AAH02586.1| Polymerase (RNA) III (DNA directed) polypeptide C (62kD) [Homo sapiens] [NCBI NR]
  • gi|119591842|gb|EAW71436.1| polymerase (RNA) III (DNA directed) polypeptide C (62kD), isoform CRA_b [Homo sapiens] [NCBI NR]
  • gi|119591841|gb|EAW71435.1| polymerase (RNA) III (DNA directed) polypeptide C (62kD), isoform CRA_b [Homo sapiens] [NCBI NR]
  • polymerase (RNA) III (DNA directed) polypeptide C (62kD) [HGNC (HUGO)]
  • DNA-directed RNA polymerase III subunit C (EC 2.7.7.6) (DNA-directed III 62 kDa polypeptide) (RNA polymerase III C62 subunit) (RPC3) - Homo sapiens (Human) [Swiss-Prot]
  • (Q9BUI4) DNA-directed RNA polymerase III 62 kDa polypeptide (EC 2.7.7.6) (RNA polymerase C subunit 3) (RPC3) (RNA polymerase III C62 subunit) [Swiss-Prot]
  • DNA-directed RNA polymerase III subunit RPC3 OS=Homo sapiens GN=POLR3C PE=1 SV=1 [Swiss-Prot]
  • Similar to polymerase [hmr_yeast5_DM3-1_pombe.fasta]
  • polymerase (RNA) III (DNA directed) (62kD) [HMR_022704.fasta]
  • polymerase (RNA) III (DNA directed) polypeptide C (62kD); polymerase (RNA) III (DNA directed) (62kD) [071204_hmrz_cont.fasta]
  • polymerase (RNA) III (DNA directed) polypeptide C (62kD) [Homo sapiens]gi|12803519|gb|AAH02586.1| Polymerase (RNA) III (DNA directed) polypeptide C (62kD) [Homo sapiens]gi|20159753|gb|AAM12033.1| RNA polymerase III subunit RPC62 [Homo sapiens] [nrdb_11152004_Chlamydomonas]
  • DNA-directed RNA polymerase III 62 kDa polypeptide (RNA polymerase C subunit 3) (RPC3) (RNA polymerase III C62 subunit) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 DNA-directed RNA polymerase III 62 kDa polypeptide [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_006468) polymerase (RNA) III (DNA directed) (62kD) [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • polymerase (RNA) III (DNA directed) polypeptide C (62kD) [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • polymerase (RNA) III (DNA directed) polypeptide C (62kD); polymerase (RNA) III (DNA directed) (62kD) [Homo sapiens] [HumanGallus06162005.fasta]
  • polymerase (RNA) III (DNA directed) (62kD) [Homo sapiens] [human-NCBI-042104-rand.fasta]
  • DNA-directed RNA polymerase III subunit RPC3 (RNA polymerase III subunit C3) (DNA-directed RNA polymerase III subunit C) (DNA-directed III 62 kDa polypeptide) (RPC62) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • polymerase (RNA) III (DNA directed) polypeptide C (62kD), isoform CRA_b [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Polymerase (RNA) III (DNA directed) polypeptide C (62kD) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • RNA polymerase III subunit RPC62 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 DNA-directed RNA polymerase III subunit C [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 DNA-DIRECTED RNA POLYMERASE III 62 KDA POLYPEPTIDE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • RecName: Full=DNA-directed RNA polymerase III subunit RPC3; Short=RNA polymerase III subunit C3; AltName: Full=DNA-directed RNA polymerase III subunit C; AltName: Full=DNA-directed III 62 kDa polypeptide; AltName: Full=RPC62 [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=POLR3C DNA-directed RNA polymerase III subunit RPC3 [human-ipi-250309-contam.fasta]
  • DNA-directed RNA polymerase III subunit C (DNA-directed III 62 kDa polypeptide) (RNA polymerase III C62 subunit) (RPC3) [nr-271106-contam.fasta]
  • IPI:IPI00007948.2|SWISS-PROT:Q9BUI4|TREMBL:Q53F76|ENSEMBL:ENSP00000334564|REFSEQ:NP_006459|H-INV:HIT000031014|VEGA:OTTHUMP00000015591 Tax_Id=9606 Gene_Symbol=POLR3C DNA-directed RNA polymerase III subunit RPC3 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=POLR3C DNA-directed RNA polymerase III subunit RPC3 ENSG00000186141 IPI00007948 IPI00642130 [drosphohumanreversed.fasta]
  • DNA-directed RNA polymerase III subunit RPC3 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Q9BUI4;O15317;Q9Y3R6; RecName: Full=DNA-directed RNA polymerase III subunit RPC3; AltName: Full=DNA-directed RNA polymerase III subunit C; AltName: Full=RNA polymerase III 62 kDa subunit; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • DNA-directed RNA polymerase III subunit RPC3 OS=Homo sapiens GN=POLR3C [011711_HMR.fasta]
  • GeneSymbol=POLR3C Synonyms=RPC3|RPC62 DNA-directed RNA polymerase III subunit RPC3 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00007948.2|SWISS-PROT:Q9BUI4|TREMBL:Q53F76;Q9BT08|ENSEMBL:ENSP00000334564|REFSEQ:NP_006459|H-INV:HIT000031014|VEGA:OTTHUMP00000015591 Tax_Id=9606 Gene_Symbol=POLR3C DNA-directed RNA polymerase III subunit RPC3 [ipi.HUMAN.20110912.fasta]
  • DNA-directed RNA polymerase III subunit RPC3 GN=POLR3C [Doctor+uniprot-HUMAN-120911.fasta]
  • Polymerase (RNA) III (DNA directed) polypeptide C (62kD), isoform CRA_b OS=Homo sapiens GN=POLR3C PE=4 SV=1 [uniprot-human-031015-contam.fasta]
    • Organism: Homo sapiens
    Length: 534 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQAEIKLCS LLLQEHFGEI VEKIGVHLIR TGSQPLRVIA HDTGTSLDQV KKALCVLVQH  60
   61 NLVSYQVHKR GVVEYEAQCS RVLRMLRYPR YIYTTKTLYS DTGELIVEEL LLNGKLTMSA 120
  121 VVKKVADRLT ETMEDGKTMD YAEVSNTFVR LADTHFVQRC PSVPTTENSD PGPPPPAPTL 180
  181 VINEKDMYLV PKLSLIGKGK RRRSSDEDAA GEPKAKRPKY TTDNKEPIPD DGIYWQANLD 240
  241 RFHQHFRDQA IVSAVANRMD QTSSEIVRTM LRMSEITTSS SAPFTQPLSS NEIFRSLPVG 300
  301 YNISKQVLDQ YLTLLADDPL EFVGKSGDSG GGMYVINLHK ALASLATATL ESVVQERFGS 360
  361 RCARIFRLVL QKKHIEQKQV EDFAMIPAKE AKDMLYKMLS ENFMSLQEIP KTPDHAPSRT 420
  421 FYLYTVNILS AARMLLHRCY KSIANLIERR QFETKENKRL LEKSQRVEAI IASMQATGAE 480
  481 EAQLQEIEEM ITAPERQQLE TLKRNVNKLD ASEIQVDETI FLLESYIECT MKRQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..134] Pfam 29.251812 No description for PF08221.2 was found. No confident structure predictions are available.
    2 View Details [135..330] Pfam 41.045757 No description for PF05645.4 was found. No confident structure predictions are available.
    3 View Details [331..534] FFAS03 2.53 An extended winged helix domain in general transcription factor E/IIE alpha


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle