YRC Public Data Repository - Protein Structure Prediction

Protein:	POLR3C
Organism:	Homo sapiens
Length:	534 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for POLR3C.

Description	E-value	Query Range	Subject Range
RPC3_BOVIN - DNA-directed RNA polymerase III subunit RPC3 OS=Bos taurus GN=POLR3C PE=2 SV=1	0.0	[1..533]	[1..533]
gi\|73981410 - gi\|73981410\|ref\|XP_540277.2\| PREDICTED: similar to polymerase (RNA) III (DNA directed) polypeptide C...	0.0	[1..534]	[1..534]
RPC3_MOUSE - DNA-directed RNA polymerase III subunit RPC3 OS=Mus musculus GN=Polr3c PE=1 SV=1	0.0	[1..534]	[1..533]
gi\|4753153 - gi\|4753153\|emb\|CAB41919.1\| RNA polymerase III subunit [Homo sapiens]	0.0	[1..534]	[1..534]
RPC3_RAT - DNA-directed RNA polymerase III subunit RPC3 OS=Rattus norvegicus GN=Polr3c PE=2 SV=1	0.0	[1..534]	[1..533]
gi\|114558429 - gi\|114558429\|ref\|XP_001161518.1\| PREDICTED: polymerase (RNA) III (DNA directed) polypeptide C (62kD)...	0.0	[1..508]	[1..508]
RPC3_DANRE - DNA-directed RNA polymerase III subunit RPC3 OS=Danio rerio GN=polr3c PE=2 SV=1	0.0	[1..534]	[1..539]
gi\|148234765, gi... - gi\|49670421\|gb\|AAH75179.1\| Polr3c-prov protein [Xenopus laevis], gi\|148234765\|ref\|NP_001086474.1\| po...	0.0	[1..530]	[1..525]

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Predicted Domain #1

Region A:
Residues: [1-134]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQAEIKLCS LLLQEHFGEI VEKIGVHLIR TGSQPLRVIA HDTGTSLDQV KKALCVLVQH  60
   61 NLVSYQVHKR GVVEYEAQCS RVLRMLRYPR YIYTTKTLYS DTGELIVEEL LLNGKLTMSA 120
  121 VVKKVADRLT ETME

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	29.251812
Match:	PF08221.2
Description:	No description for PF08221.2 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [135-330]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGKTMDYAEV SNTFVRLADT HFVQRCPSVP TTENSDPGPP PPAPTLVINE KDMYLVPKLS  60
   61 LIGKGKRRRS SDEDAAGEPK AKRPKYTTDN KEPIPDDGIY WQANLDRFHQ HFRDQAIVSA 120
  121 VANRMDQTSS EIVRTMLRMS EITTSSSAPF TQPLSSNEIF RSLPVGYNIS KQVLDQYLTL 180
  181 LADDPLEFVG KSGDSG

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	41.045757
Match:	PF05645.4
Description:	No description for PF05645.4 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [331-534]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGMYVINLHK ALASLATATL ESVVQERFGS RCARIFRLVL QKKHIEQKQV EDFAMIPAKE  60
   61 AKDMLYKMLS ENFMSLQEIP KTPDHAPSRT FYLYTVNILS AARMLLHRCY KSIANLIERR 120
  121 QFETKENKRL LEKSQRVEAI IASMQATGAE EAQLQEIEEM ITAPERQQLE TLKRNVNKLD 180
  181 ASEIQVDETI FLLESYIECT MKRQ

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	2.53
Match:	1q1hA
Description:	An extended winged helix domain in general transcription factor E/IIE alpha
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits