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Protein Overview: PGRMC1

General Information:
Name(s) found: PGRMC1 [HGNC (HUGO)]
Description(s) found:
Found 37 descriptions.
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  • progesterone receptor membrane component 1 [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 195 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAEDVVATG ADPSDLESGG LLHEIFTSPL NLLLLGLCIF LLYKIVRGDQ PAASGDSDDD  60
   61 EPPPLPRLKR RDFTPAELRR FDGVQDPRIL MAINGKVFDV TKGRKFYGPE GPYGVFAGRD 120
  121 ASRGLATFCL DKEALKDEYD DLSDLTAAQQ ETLSDWESQF TFKYHHVGKL LKEGEEPTVY 180
  181 SDEEEPKDES ARKND

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..195] PSI-BLAST 21.39794 Solution structure of a putative steroid-binding protein from Arabidopsis

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.76718756313666 bayes_pls_golite062009
  • transporter activity
    		•  0.920087041947819 bayes_pls_golite062009
  • signal transducer activity
    		•  0.76215529135227 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.76215529135227 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.739503099682459 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.535501995010142 bayes_pls_golite062009
  • receptor activity
    		•  0.460667473683829 bayes_pls_golite062009
  • protein binding
    		•  0.368622185753917 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.314610777889032 bayes_pls_golite062009
  • steroid binding
    		•  0.177535173083536 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.0578908750434612 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle