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Protein Overview: PMVK

General Information:
Name(s) found: PMVK [HGNC (HUGO)]
Description(s) found:
Found 32 descriptions.
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  • phosphomevalonate kinase [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 192 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPLGGAPRL VLLFSGKRKS GKDFVTEALQ SRLGADVCAV LRLSGPLKEQ YAQEHGLNFQ  60
   61 RLLDTSTYKE AFRKDMIRWG EEKRQADPGF FCRKIVEGIS QPIWLVSDTR RVSDIQWFRE 120
  121 AYGAVTQTVR VVALEQSRQQ RGWVFTPGVD DAESECGLDN FGDFDWVIEN HGVEQRLEEQ 180
  181 LENLIEFIRS RL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..192] FFAS03 3.61 Deoxynucleoside monophosphate kinase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.95375255800529 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.64145281433737 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.64143924531769 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.63636295221546 bayes_pls_golite062009
  • nucleotide binding
    		•  1.63198326745256 bayes_pls_golite062009
  • ATP binding
    		•  1.39627059522231 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.36808893759893 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.34788842797256 bayes_pls_golite062009
  • kinase activity
    		•  1.33467594210663 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.1110354773275 bayes_pls_golite062009
  • catalytic activity
    		•  0.942640875796745 bayes_pls_golite062009
  • protein kinase activity
    		•  0.881833260481293 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.751825354522891 bayes_pls_golite062009
  • hydrolase activity
    		•  0.501341907111163 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.383901364132511 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.29022187219315 bayes_pls_golite062009
  • transferase activity
    		•  0.225487723736763 bayes_pls_golite062009
  • protein binding
    		•  0.102043618157662 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle