Protein Overview: LAS1L

General Information:
Name(s) found:	LAS1L [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|73920837\|sp\|Q9Y4W2.2\|LAS1L_HUMAN RecName: Full=LAS1-like protein [NCBI NR] gi\|57471636\|emb\|CAI42835.1\| LAS1-like (S. cerevisiae) [Homo sapiens] [NCBI NR] gi\|27462078\|gb\|AAO15306.1\|AF116730_1 MSTP060 [Homo sapiens] [NCBI NR] gi\|15778927\|gb\|AAH14545.1\| LAS1-like (S. cerevisiae) [Homo sapiens] [NCBI NR] gi\|13654270\|ref\|NP_112483.1\| LAS1-like [Homo sapiens] [NCBI NR] gi\|119625806\|gb\|EAX05401.1\| LAS1-like (S. cerevisiae), isoform CRA_a [Homo sapiens] [NCBI NR] gi\|10434062\|dbj\|BAB14114.1\| unnamed protein product [Homo sapiens] [NCBI NR] LAS1-like (S. cerevisiae) [HGNC (HUGO)] Ribosomal biogenesis protein LAS1L OS=Homo sapiens GN=LAS1L PE=1 SV=2 [Swiss-Prot] Hypothetical protein FLJ12525 [hmr_yeast5_DM3-1_pombe.fasta] hypothetical protein FLJ12525 [HMR_022704.fasta] hypothetical protein FLJ12525 [Homo sapiens]gi\|10434062\|dbj\|BAB14114.1\| unnamed protein product [Homo sapiens]gi\|15778927\|gb\|AAH14545.1\| Hypothetical protein FLJ12525 [Homo sapiens]gi\|27462078\|gb\|AAO15306.1\| MSTP060 [Homo sapiens] [nrdb_11152004_Chlamydomonas] LAS1-like protein [Yateslab_human_na_07-28-2006_reversed.fasta] Tax_Id=9606 Splice Isoform 1 of LAS1-like protein [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta] (NM_031206) hypothetical protein FLJ12525 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] LAS1-like [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta] hypothetical protein FLJ12525 [Homo sapiens] [HumanGallus06162005.fasta] LAS1-like (S. cerevisiae) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] LAS1-like (S. cerevisiae), isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] MSTP060 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tax_Id=9606 Isoform 1 of LAS1-like protein [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta] Tax_Id=9606 HYPOTHETICAL PROTEIN FLJ12525 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=9606 Gene_Symbol=LAS1L Isoform 1 of LAS1-like protein [human-ipi-250309-contam.fasta] novel protein [Homo sapiens] [nr-271106-contam.fasta] LAS1-like isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_na_02-15-2010_reversed.fasta] IPI:IPI00641990.1\|SWISS-PROT:Q9Y4W2-1\|TREMBL:A9X410\|ENSEMBL:ENSP00000363944\|REFSEQ:NP_112483\|H-INV:HIT000036767\|VEGA:OTTHUMP00000023436 Tax_Id=9606 Gene_Symbol=LAS1L Isoform 1 of LAS1-like protein [ipi.HUMAN.fasta.20090807] [human_BMb_040710_contam.fasta] Tax_Id=9606 Gene_Symbol=LAS1L Isoform 1 of LAS1-like protein ENSG00000001497 IPI00152781 IPI00009917 IPI00645869 IPI00641990 [drosphohumanreversed.fasta] Tax_Id=9606 Gene_Symbol=LAS1L Isoform 1 of Protein LAS1 homolog [EBI-IPI_Human_3.71_03-24-2010_reversed.fasta] protein LAS1 homolog isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Protein LAS1 homolog OS=Homo sapiens GN=LAS1L PE=1 SV=2 [UniProtHuman070710.fasta] Q9Y4W2;Q5JXQ0;Q8TEN5;Q9H9V5; RecName: Full=Protein LAS1 homolog; [UniProt_Human_2010_06_06-01-2010_reversed.fasta] Isoform 1 of Protein LAS1 homolog OS=Homo sapiens GN=LAS1L [011711_HMR.fasta] IPI:IPI00641990.1\|SWISS-PROT:Q9Y4W2-1\|TREMBL:A9X410\|ENSEMBL:ENSP00000363944\|REFSEQ:NP_112483\|H-INV:HIT000036767\|VEGA:OTTHUMP00000023436 Tax_Id=9606 Gene_Symbol=LAS1L Isoform 1 of Protein LAS1 homolog [ipi.HUMAN.fasta.20100406] GeneSymbol=LAS1L Synonyms=FLJ12525\|FLJ30133\|FLJ45274\|dJ475B7.2 protein LAS1 homolog isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] Ribosomal biogenesis protein LAS1L GN=LAS1L [Doctor+uniprot-HUMAN-120911.fasta]
Organism:	Homo sapiens
Length:	734 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSWESGAGPG LGSQGMDLVW SAWYGKCVKG KGSLPLSAHG IVVAWLSRAE WDQVTVYLFC  60
   61 DDHKLQRYAL NRITVWRSRS GNELPLAVAS TADLIRCKLL DVTGGLGTDE LRLLYGMALV 120
  121 RFVNLISERK TKFAKVPLKC LAQEVNIPDW IVDLRHELTH KKMPHINDCR RGCYFVLDWL 180
  181 QKTYWCRQLE NSLRETWELE EFREGIEEED QEEDKNIVVD DITEQKPEPQ DDGKSTESDV 240
  241 KADGDSKGSE EVDSHCKKAL SHKELYERAR ELLVSYEEEQ FTVLEKFRYL PKAIKAWNNP 300
  301 SPRVECVLAE LKGVTCENRE AVLDAFLDDG FLVPTFEQLA ALQIEYEDGQ TEVQRGEGTD 360
  361 PKSHKNVDLN DVLVPKPFSQ FWQPLLRGLH SQNFTQALLE RMLSELPALG ISGIRPTYIL 420
  421 RWTVELIVAN TKTGRNARRF SAGQWEARRG WRLFNCSASL DWPRMVESCL GSPCWASPQL 480
  481 LRIIFKAMGQ GLPDEEQEKL LRICSIYTQS GENSLVQEGS EASPIGKSPY TLDSLYWSVK 540
  541 PASSSFGSEA KAQQQEEQGS VNDVKEEEKE EKEVLPDQVE EEEENDDQEE EEEDEDDEDD 600
  601 EEEDRMEVGP FSTGQESPTA ENARLLAQKR GALQGSAWQV SSEDVRWDTF PLGRMPGQTE 660
  661 DPAELMLENY DTMYLLDQPV LEQRLEPSTC KTDTLGLSCG VGSGNCSNSS SSNFEGLLWS 720
  721 QGQLHGLKTG LQLF

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	None Entered	Sample pIC145 from april 2005	Okada, M., et al. (2006)
View Run	gi\|14317902, gi\|...	No Comments	Cheeseman, I.M., et al. (2004)
View Run	MIS12	No Comments	Cheeseman, I.M., et al. (2004)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..201]	Pfam	93.236572	No description for PF04031.2 was found. No confident structure predictions are available.
2	View Details	[202..358]	deduced	N/A	No confident structure predictions are available.
3	View Details	[359..599]	deduced	N/A	No confident structure predictions are available.
4	View Details	[600..734]	MSA	1.002938	View MSA. No confident structure predictions are available.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.96

Protein Overview: LAS1L

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: