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View Structure Prediction Details

Protein: LAS1L
Organism: Homo sapiens
Length: 734 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LAS1L.

Description E-value Query
Range
Subject
Range
gi|17939650, gi|... - gi|5578958|emb|CAB51351.1| LAS1-like (S. cerevisiae) [Homo sapiens], gi|17939650|gb|AAH19302.1| LAS1...
1216.0 [0..1] [734..1]
gi|74007520 - gi|74007520|ref|XP_538062.2| PREDICTED: similar to LAS1-like [Canis familiaris]
1120.0 [0..3] [734..34]
gi|223462902, gi... - gi|71979675|ref|NP_690035.2| LAS1-like [Mus musculus], gi|223462902|gb|AAI41156.1| LAS1-like (S. cer...
875.0 [0..16] [564..1]
gi|109510859, gi... - gi|109512022|ref|XP_001067427.1| PREDICTED: similar to LAS1-like isoform 1 [Rattus norvegicus], gi|1...
834.0 [0..16] [565..1]
gi|115305237, gi... - gi|116003853|ref|NP_001070283.1| LAS1-like [Bos taurus], gi|115305237|gb|AAI23894.1| LAS1-like (S. c...
586.0 [0..366] [734..9]
gi|49071194, gi|... - gi|71010809|ref|XP_758418.1| hypothetical protein UM02271.1 [Ustilago maydis 521], ref|XP_399886.1| ...
461.0 [0..49] [420..15]

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Predicted Domain #1
Region A:
Residues: [1-201]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSWESGAGPG LGSQGMDLVW SAWYGKCVKG KGSLPLSAHG IVVAWLSRAE WDQVTVYLFC  60
   61 DDHKLQRYAL NRITVWRSRS GNELPLAVAS TADLIRCKLL DVTGGLGTDE LRLLYGMALV 120
  121 RFVNLISERK TKFAKVPLKC LAQEVNIPDW IVDLRHELTH KKMPHINDCR RGCYFVLDWL 180
  181 QKTYWCRQLE NSLRETWELE E

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 93.236572
Match: PF04031.2
Description: No description for PF04031.2 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [202-358]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FREGIEEEDQ EEDKNIVVDD ITEQKPEPQD DGKSTESDVK ADGDSKGSEE VDSHCKKALS  60
   61 HKELYERARE LLVSYEEEQF TVLEKFRYLP KAIKAWNNPS PRVECVLAEL KGVTCENREA 120
  121 VLDAFLDDGF LVPTFEQLAA LQIEYEDGQT EVQRGEG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [359-599]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TDPKSHKNVD LNDVLVPKPF SQFWQPLLRG LHSQNFTQAL LERMLSELPA LGISGIRPTY  60
   61 ILRWTVELIV ANTKTGRNAR RFSAGQWEAR RGWRLFNCSA SLDWPRMVES CLGSPCWASP 120
  121 QLLRIIFKAM GQGLPDEEQE KLLRICSIYT QSGENSLVQE GSEASPIGKS PYTLDSLYWS 180
  181 VKPASSSFGS EAKAQQQEEQ GSVNDVKEEE KEEKEVLPDQ VEEEEENDDQ EEEEEDEDDE 240
  241 D

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [600-734]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEEEDRMEVG PFSTGQESPT AENARLLAQK RGALQGSAWQ VSSEDVRWDT FPLGRMPGQT  60
   61 EDPAELMLEN YDTMYLLDQP VLEQRLEPST CKTDTLGLSC GVGSGNCSNS SSSNFEGLLW 120
  121 SQGQLHGLKT GLQLF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle