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Protein Overview: LAS1_ARATH

General Information:
Name(s) found: LAS1_ARATH [Swiss-Prot]
Description(s) found:
Found 8 descriptions.
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  • Lanosterol synthase OS=Arabidopsis thaliana GN=LAS1 PE=2 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 756 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: pentacyclic triterpenoid biosynthetic process [ISS]
    Molecular Function: lanosterol synthase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWRLKLSEGD EESVNQHVGR QFWEYDNQFG TSEERHHINH LRSNFTLNRF SSKHSSDLLY  60
   61 RFQCWKEKGK GMERLPQVKV KEGEERLINE EVVNVTLRRS LRFYSILQSQ DGFWPGDYGG 120
  121 PLFLLPALVI GLYVTEVLDG TLTAQHQIEI RRYLYNHQNK DGGWGLHVEG NSTMFCTVLS 180
  181 YVALRLMGEE LDGGDGAMES ARSWIHHHGG ATFIPSWGKF WLSVLGAYEW SGNNPLPPEL 240
  241 WLLPYSLPFH PGRMWCHCRM VYLPMSYLYG RRFVCRTNGT ILSLRRELYT IPYHHIDWDT 300
  301 ARNQCAKEDL YYPHPKIQDV LWSCLNKFGE PLLERWPLNN LRNHALQTVM QHIHYEDQNS 360
  361 HYICIGPVNK VLNMLCCWVE SSNSEAFKSH LSRIKDYLWV AEDGMKMQGY NGSQLWDVTL 420
  421 AVQAILATNL VDDYGLMLKK AHNYIKNTQI RKDTSGDPGL WYRHPCKGGW GFSTGDNPWP 480
  481 VSDCTAEALK AALLLSQMPV NLVGEPMPEE HLVDAVNFIL SLQNKNGGFA SYELTRSYPE 540
  541 LEVINPSETF GDIIIDYQYV ECTSAAIQGL VLFTTLNSSY KRKEIVGSIN KAVEFIEKTQ 600
  601 LPDGSWYGSW GVCFTYATWF GIKGMLASGK TYESSLCIRK ACGFLLSKQL CCGGWGESYL 660
  661 SCQNKVYTNL PGNKSHIVNT SWALLALIEA GQASRDPMPL HRGAKSLINS QMEDGDYPQQ 720
  721 EILGVFNRNC MISYSAYRNI FPIWALGEYR KLMLSL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..756] PSI-BLAST 1000.0 Structure of human OSC in complex with Lanosterol


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.73

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle