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View Structure Prediction Details

Protein: LAS1_ARATH
Organism: Arabidopsis thaliana
Length: 756 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LAS1_ARATH.

Description E-value Query
Range
Subject
Range
CAS1_GLYGL - Cycloartenol synthase OS=Glycyrrhiza glabra GN=GgCAS1 PE=1 SV=1
916.0 [0..1] [755..1]
gi|2627181, gi|7... - pir||JC5590 cycloartenol synthase (EC 5.4.99.8) - garden pea, gi|2627181|dbj|BAA23533.1| cycloarten...
911.0 [0..1] [755..1]
gi|83016479 - gi|83016479|dbj|BAE53431.1| cycloartenol synthase [Lotus japonicus]
909.0 [0..1] [755..1]
CAS1_RICCO - Cycloartenol synthase OS=Ricinus communis PE=1 SV=1
904.0 [0..1] [755..1]
gi|452446 - gi|452446|gb|AAC04931.1| cycloartenol synthase; (S)-2,3-epoxysqualene mutase [Arabidopsis thaliana]
902.0 [0..1] [754..1]
gi|46242746 - gi|46242746|gb|AAS83469.1| cycloartenol synthase [Bupleurum kaoi]
900.0 [0..1] [756..1]
CAS2_BETPL - Cycloartenol synthase 2 OS=Betula platyphylla GN=CASBPX2 PE=1 SV=1
898.0 [0..1] [755..1]
CAS1_PANGI - Cycloartenol Synthase OS=Panax ginseng GN=OSCPNX1 PE=1 SV=1
896.0 [0..1] [755..1]

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Predicted Domain #1
Region A:
Residues: [1-756]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWRLKLSEGD EESVNQHVGR QFWEYDNQFG TSEERHHINH LRSNFTLNRF SSKHSSDLLY  60
   61 RFQCWKEKGK GMERLPQVKV KEGEERLINE EVVNVTLRRS LRFYSILQSQ DGFWPGDYGG 120
  121 PLFLLPALVI GLYVTEVLDG TLTAQHQIEI RRYLYNHQNK DGGWGLHVEG NSTMFCTVLS 180
  181 YVALRLMGEE LDGGDGAMES ARSWIHHHGG ATFIPSWGKF WLSVLGAYEW SGNNPLPPEL 240
  241 WLLPYSLPFH PGRMWCHCRM VYLPMSYLYG RRFVCRTNGT ILSLRRELYT IPYHHIDWDT 300
  301 ARNQCAKEDL YYPHPKIQDV LWSCLNKFGE PLLERWPLNN LRNHALQTVM QHIHYEDQNS 360
  361 HYICIGPVNK VLNMLCCWVE SSNSEAFKSH LSRIKDYLWV AEDGMKMQGY NGSQLWDVTL 420
  421 AVQAILATNL VDDYGLMLKK AHNYIKNTQI RKDTSGDPGL WYRHPCKGGW GFSTGDNPWP 480
  481 VSDCTAEALK AALLLSQMPV NLVGEPMPEE HLVDAVNFIL SLQNKNGGFA SYELTRSYPE 540
  541 LEVINPSETF GDIIIDYQYV ECTSAAIQGL VLFTTLNSSY KRKEIVGSIN KAVEFIEKTQ 600
  601 LPDGSWYGSW GVCFTYATWF GIKGMLASGK TYESSLCIRK ACGFLLSKQL CCGGWGESYL 660
  661 SCQNKVYTNL PGNKSHIVNT SWALLALIEA GQASRDPMPL HRGAKSLINS QMEDGDYPQQ 720
  721 EILGVFNRNC MISYSAYRNI FPIWALGEYR KLMLSL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1000.0
Match: 1w6kA
Description: Structure of human OSC in complex with Lanosterol
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
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