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Protein Overview: NARFL

General Information:
Name(s) found: NARFL [HGNC (HUGO)]
Description(s) found:
Found 34 descriptions.
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  • nuclear prelamin A recognition factor-like [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 476 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASPFSGALQ LTDLDDFIGP SQECIKPVKV EKRAGSGVAK IRIEDDGSYF QINQDGGTRR  60
   61 LEKAKVSLND CLACSGCITS AETVLITQQS HEELKKVLDA NKMAAPSQQR LVVVSVSPQS 120
  121 RASLAARFQL NPTDTARKLT SFFKKIGVHF VFDTAFSRHF SLLESQREFV RRFRGQADCR 180
  181 QALPLLASAC PGWICYAEKT HGSFILPHIS TARSPQQVMG SLVKDFFAQQ QHLTPDKIYH 240
  241 VTVMPCYDKK LEASRPDFFN QEHQTRDVDC VLTTGEVFRL LEEEGVSLPD LEPAPLDSLC 300
  301 SGASAEEPTS HRGGGSGGYL EHVFRHAARE LFGIHVAEVT YKPLRNKDFQ EVTLEKEGQV 360
  361 LLHFAMAYGF RNIQNLVQRL KRGRCPYHYV EVMACPSGCL NGGGQLQAPD RPSRELLQHV 420
  421 ERLYGMVRAE APEDAPGVQE LYTHWLQGTD SECAGRLLHT QYHAVEKAST GLGIRW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..476] PSI-BLAST 136.0 Fe-only hydrogenase, catalytic domain; Fe-only hydrogenase, N-terminal domain; Fe-only hydrogenase, second domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.47874003627413 bayes_pls_golite062009
  • NADH dehydrogenase (ubiquinone) activity
    		•  1.31458462821219 bayes_pls_golite062009
  • iron-sulfur cluster binding
    		•  1.18054918348653 bayes_pls_golite062009
  • metal cluster binding
    		•  1.18054918348653 bayes_pls_golite062009
  • NADH dehydrogenase activity
    		•  1.10428419414285 bayes_pls_golite062009
  • lamin binding
    		•  0.863386378061341 bayes_pls_golite062009
  • NADH dehydrogenase (quinone) activity
    		•  0.778342926116907 bayes_pls_golite062009
  • catalytic activity
    		•  0.488483980994331 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
    		•  0.312816353615077 bayes_pls_golite062009
  • ferredoxin hydrogenase activity
    		•  0.278768281741128 bayes_pls_golite062009
  • oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
    		•  0.278768281741128 bayes_pls_golite062009
  • protein binding
    		•  0.221871950373022 bayes_pls_golite062009
  • electron carrier activity
    		•  0.0554226204149908 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle