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Protein Overview: PANK1

General Information:
Name(s) found: PANK1 [HGNC (HUGO)]
Description(s) found:
Found 28 descriptions.
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  • pantothenate kinase 1 [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 598 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKLVGGGGG QDWACSVAGT SLGGEEAAFE VARPGDQGKA GGGSPGWGCA GIPDSAPGAG  60
   61 VLQAGAVGPA RGGQGAEEVG ESAGGGEERR VRHPQAPALR LLNRKPQGGS GEIKTPENDL 120
  121 QRGRLSRGPR TAPPAPGMGD RSGQQERSVP HSPGAPVGTS AAAVNGLLHN GFHPPPVQPP 180
  181 HVCSRGPVGG SDAAPQRLPL LPELQPQPLL PQHDSPAKKC RLRRRMDSGR KNRPPFPWFG 240
  241 MDIGGTLVKL VYFEPKDITA EEEQEEVENL KSIRKYLTSN TAYGKTGIRD VHLELKNLTM 300
  301 CGRKGNLHFI RFPSCAMHRF IQMGSEKNFS SLHTTLCATG GGAFKFEEDF RMIADLQLHK 360
  361 LDELDCLIQG LLYVDSVGFN GKPECYYFEN PTNPELCQKK PYCLDNPYPM LLVNMGSGVS 420
  421 ILAVYSKDNY KRVTGTSLGG GTFLGLCCLL TGCETFEEAL EMAAKGDSTN VDKLVKDIYG 480
  481 GDYERFGLQG SAVASSFGNM MSKEKRDSIS KEDLARATLV TITNNIGSIA RMCALNENID 540
  541 RVVFVGNFLR INMVSMKLLA YAMDFWSKGQ LKALFLEHEG YFGAVGALLE LFKMTDDK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..235] PSI-BLAST 7.0 No description for 1y0fA was found.
    2 View Details [236..598] PSI-BLAST 150.0 No description for 2i7nA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • structural constituent of cytoskeleton
    		•  2.46121037473545 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.20983242331685 bayes_pls_golite062009
  • binding
    		•  1.54134537534661 bayes_pls_golite062009
  • pantothenate kinase activity
    		•  1.44039088435404 bayes_pls_golite062009
  • protein binding
    		•  1.16405332128302 bayes_pls_golite062009
  • actin binding
    		•  1.03829083423378 bayes_pls_golite062009
  • structural molecule activity
    		•  0.416185949451087 bayes_pls_golite062009
  • myosin binding
    		•  0.31501932970343 bayes_pls_golite062009
  • catalytic activity
    		•  0.296484721581333 bayes_pls_golite062009
  • kinase activity
    		•  0.18855544139935 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.164763891002303 bayes_pls_golite062009
  • transferase activity
    		•  0.105619024604158 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.88

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle