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Protein Overview: gi|21039411, gi|...

General Information:
Name(s) found: gi|21955172 [NCBI NR]
gi|21039411 [NCBI NR]
gi|119600098 [NCBI NR]
Description(s) found:
Found 26 descriptions.
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  • gi|21955172|ref|NP_665696.1| pleckstrin homology-like domain, family B, member 2 isoform c [Homo sapiens] [NCBI NR]
  • gi|21039411|gb|AAM33634.1|AF506820_1 hypothetical protein [Homo sapiens] [NCBI NR]
  • gi|119600098|gb|EAW79692.1| pleckstrin homology-like domain, family B, member 2, isoform CRA_c [Homo sapiens] [NCBI NR]
    • Organism: Homo sapiens
    Length: 1210 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEHSYIQKE LDLQNGSLEE DSVVHSVEND SQNMMESLSP KKYSSSLRFK ANGDYSGSYL  60
   61 TLSQPVPAKR SPSPLGTSVR SSPSLAKIQG SKQFSYDGTD KNIPMKPPTP LLNTTSSLSG 120
  121 YPLGRADFDH YTGRDSERAL RLSEKPPYSK YSSRHKSHDN VYSLGGLEGR KASGSLLAMW 180
  181 NGSSLSDAGP PPISRSGAAS MPSSPKQARK MSIQDSLALQ PKLTRHKELA SENINLRTRK 240
  241 YSSSSLSHMG AYSRSLPRLY RATENQLTPL SLPPRNSLGN SKRTKLGEKD LPHSVIDNDN 300
  301 YLNFSSLSSG ALPYKTSASE GNPYVSSTLS VPASPRVARK MLLASTSSCA SDDFDQASYV 360
  361 GTNPSHSLLA GESDRVFATR RNFSCGSVEF DEADLESLRQ ASGTPQPALR ERKSSISSIS 420
  421 GRDDLMDYHR RQREERLREQ EMERLERQRL ETILSLCAEY TKPDSRLSTG TTVEDVQKIN 480
  481 KELEKLQLSD EESVFEEALM SPDTRYRCHR KDSLPDADLA SCGSLSQSSA SFFTPRSTRN 540
  541 DELLSDLTRT PPPPSSTFPK ASSESSYLSI LPKTPEGISE EQRSQELAAM EETRIVILNN 600
  601 LEELKQKIKD INDQMDESFR ELDMECALLD GEQKSETTEL MKEKEILDHL NRKIAELEKN 660
  661 IVGEKTKDAD LLDVESKHFE DLEFQQLEHE SRLDEEKENL TQQLLREVAE YQRNIVSRKE 720
  721 KISALKKQAN HIVQQAQREQ DHFVKEKNNL IMMLQREKEN LCNLEKKYSS LSGGKGFPVN 780
  781 PNTLKEGYIS VNEINEPCGN STNLSPSTQF PADADAVATE PATAVLASQP QSKEHFRSLE 840
  841 ERKKQHKEGL YLSDTLPRKK TTSSISPHFS SATMGRSITP KAHLPLGQSN SCGSVLPPSL 900
  901 AAMAKDSESR RMLRGYNHQQ MSEGHRQKSE FYNRTASESN VYLNSFHYPD HSYKDQAFDT 960
  961 LSLDSSDSME TSISACSPDN ISSASTSNIA RIEEMERLLK QAHAEKTRLL ESREREMEAK1020
 1021 KRALEEEKRR REILEKRLQE ETSQRQKLIE KEVKIRERQR AQARPLTRYL PVRKEDFDLR1080
 1081 SHVETAGHNI DTCYHVSITE KTCRGFLIKM GGKIKTWKKR WFVFDRNKRT FSYYADKHET1140
 1141 KLKGVIYFQA IEEVYYDHLK NANKSPNPLL TFSVKTHDRI YYMVAPSPEA MRIWMDVIVT1200
 1201 GAEGYTHFLL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run gi|14317902, gi|... No Comments Cheeseman, I.M., et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..196] MSA 5.280996 View MSA. No confident structure predictions are available.
    2 View Details [197..291] deduced N/A No confident structure predictions are available.
    3 View Details [292..463] PSI-BLAST 6.522879 Tropomyosin
    4 View Details [464..845] PSI-BLAST 11.0 Heavy meromyosin subfragment
    5 View Details [846..1100] FFAS03 1.09 BRCA2 helical domain; BRCA2 tower domain; OB-fold domains of BRCA2
    6 View Details [1101..1210] PSI-BLAST 20.0 Solution Structure of the C-terminal Pleckstrin Homology Domain of Sbf1 from Mouse

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6
    Term Confidence Notes
  • binding
    		•  0.597587183571285 bayes_pls_golite062009
  • protein binding
    		•  0.29116370406325 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle