YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: gi|21039411, gi|...
Organism: Homo sapiens
Length: 1210 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|21039411, gi|....

Description E-value Query
Range
Subject
Range
gi|109033079 - gi|109033079|ref|XP_001097875.1| PREDICTED: similar to pleckstrin homology-like domain, family B, me...
0.0 [1..1210] [54..1263]
gi|114588419, gi... - gi|114588421|ref|XP_001153785.1| PREDICTED: pleckstrin homology-like domain, family B, member 2 isof...
0.0 [1..1210] [1..1207]
gi|51477003 - gi|51477003|emb|CAH18447.1| hypothetical protein [Homo sapiens]
0.0 [1..1210] [28..1237]
gi|109493259 - gi|109493259|ref|XP_001064525.1| PREDICTED: similar to pleckstrin homology-like domain, family B, me...
3.0E-97 [1..1210] [1..1205]
PHLB2_MOUSE - Pleckstrin homology-like domain family B member 2 OS=Mus musculus GN=Phldb2 PE=1 SV=2
4.0E-89 [1..1210] [1..1249]

Back

Predicted Domain #1
Region A:
Residues: [1-196]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEHSYIQKE LDLQNGSLEE DSVVHSVEND SQNMMESLSP KKYSSSLRFK ANGDYSGSYL  60
   61 TLSQPVPAKR SPSPLGTSVR SSPSLAKIQG SKQFSYDGTD KNIPMKPPTP LLNTTSSLSG 120
  121 YPLGRADFDH YTGRDSERAL RLSEKPPYSK YSSRHKSHDN VYSLGGLEGR KASGSLLAMW 180
  181 NGSSLSDAGP PPISRS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [197-291]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAASMPSSPK QARKMSIQDS LALQPKLTRH KELASENINL RTRKYSSSSL SHMGAYSRSL  60
   61 PRLYRATENQ LTPLSLPPRN SLGNSKRTKL GEKDL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [292-463]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PHSVIDNDNY LNFSSLSSGA LPYKTSASEG NPYVSSTLSV PASPRVARKM LLASTSSCAS  60
   61 DDFDQASYVG TNPSHSLLAG ESDRVFATRR NFSCGSVEFD EADLESLRQA SGTPQPALRE 120
  121 RKSSISSISG RDDLMDYHRR QREERLREQE MERLERQRLE TILSLCAEYT KP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.522879
Match: 1c1gA
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [464-845]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSRLSTGTTV EDVQKINKEL EKLQLSDEES VFEEALMSPD TRYRCHRKDS LPDADLASCG  60
   61 SLSQSSASFF TPRSTRNDEL LSDLTRTPPP PSSTFPKASS ESSYLSILPK TPEGISEEQR 120
  121 SQELAAMEET RIVILNNLEE LKQKIKDIND QMDESFRELD MECALLDGEQ KSETTELMKE 180
  181 KEILDHLNRK IAELEKNIVG EKTKDADLLD VESKHFEDLE FQQLEHESRL DEEKENLTQQ 240
  241 LLREVAEYQR NIVSRKEKIS ALKKQANHIV QQAQREQDHF VKEKNNLIMM LQREKENLCN 300
  301 LEKKYSSLSG GKGFPVNPNT LKEGYISVNE INEPCGNSTN LSPSTQFPAD ADAVATEPAT 360
  361 AVLASQPQSK EHFRSLEERK KQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.0
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [846-1100]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HKEGLYLSDT LPRKKTTSSI SPHFSSATMG RSITPKAHLP LGQSNSCGSV LPPSLAAMAK  60
   61 DSESRRMLRG YNHQQMSEGH RQKSEFYNRT ASESNVYLNS FHYPDHSYKD QAFDTLSLDS 120
  121 SDSMETSISA CSPDNISSAS TSNIARIEEM ERLLKQAHAE KTRLLESRER EMEAKKRALE 180
  181 EEKRRREILE KRLQEETSQR QKLIEKEVKI RERQRAQARP LTRYLPVRKE DFDLRSHVET 240
  241 AGHNIDTCYH VSITE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.09
Match: 1miuA
Description: BRCA2 helical domain; BRCA2 tower domain; OB-fold domains of BRCA2
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [1101-1210]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTCRGFLIKM GGKIKTWKKR WFVFDRNKRT FSYYADKHET KLKGVIYFQA IEEVYYDHLK  60
   61 NANKSPNPLL TFSVKTHDRI YYMVAPSPEA MRIWMDVIVT GAEGYTHFLL 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.0
Match: 1v5uA
Description: Solution Structure of the C-terminal Pleckstrin Homology Domain of Sbf1 from Mouse
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.597587183571285 bayes_pls_golite062009
protein binding 0.29116370406325 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle