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Protein Overview: PANK4

General Information:
Name(s) found: PANK4 [HGNC (HUGO)]
Description(s) found:
Found 33 descriptions.
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  • pantothenate kinase 4 [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 773 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAECGASGSG SSGDSLDKSI TLPPDEIFRN LENAKRFAID IGGSLTKLAY YSTVQHKVAK  60
   61 VRSFDHSGKD TEREHEPPYE ISVQEEITAR LHFIKFENTY IEACLDFIKD HLVNTETKVI 120
  121 QATGGGAYKF KDLIEEKLRL KVDKEDVMTC LIKGCNFVLK NIPHEAFVYQ KDSDPEFRFQ 180
  181 TNHPHIFPYL LVNIGSGVSI VKVETEDRFE WVGGSSIGGG TFWGLGALLT KTKKFDELLH 240
  241 LASRGQHSNV DMLVRDVYGG AHQTLGLSGN LIASSFGKSA TADQEFSKED MAKSLLHMIS 300
  301 NDIGQLACLH ARLHSLDRVY FGGFFIRGHP VTMRTITYSI NFFSKGEVQA LFLRHEGYLG 360
  361 AIGAFLKGAE QDNPNQYSWG ENYAGSSGLM SASPELGPAQ RARSGTFDLL EMDRLERPLV 420
  421 DLPLLLDPPS YVPDTVDLTD DALARKYWLT CFEEALDGVV KRAVASQPDS VDAAERAEKF 480
  481 RQKYWNKLQT LRQQPFAYGT LTVRSLLDTR EHCLNEFNFP DPYSKVKQRE NGVALRCFPG 540
  541 VVRSLDALGW EERQLALVKG LLAGNVFDWG AKAVSAVLES DPYFGFEEAK RKLQERPWLV 600
  601 DSYSEWLQRL KGPPHKCALI FADNSGIDII LGVFPFVREL LLRGTEVILA CNSGPALNDV 660
  661 THSESLIVAE RIAGMDPVVH SALQEERLLL VQTGSSSPCL DLSRLDKGLA ALVRERGADL 720
  721 VVIEGMGRAV HTNYHAALRC ESLKLAVIKN AWLAERLGGR LFSVIFKYEV PAE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..404] PSI-BLAST 145.0 No description for 2i7nA was found.
    2 View Details [405..773] PSI-BLAST 122.0 X-ray structure of gene product from Arabidopsis thaliana At2g17340

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • structural constituent of cytoskeleton
    		•  2.46121037473545 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.20983242331685 bayes_pls_golite062009
  • binding
    		•  1.97067859459221 bayes_pls_golite062009
  • pantothenate kinase activity
    		•  1.44039088435404 bayes_pls_golite062009
  • carbohydrate kinase activity
    		•  1.3713660758447 bayes_pls_golite062009
  • protein binding
    		•  1.16405332128302 bayes_pls_golite062009
  • actin binding
    		•  1.03829083423378 bayes_pls_golite062009
  • structural molecule activity
    		•  0.963253603902027 bayes_pls_golite062009
  • hydrolase activity
    		•  0.921698825968978 bayes_pls_golite062009
  • kinase activity
    		•  0.90616568759573 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.797242642077629 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.59082563232385 bayes_pls_golite062009
  • hexokinase activity
    		•  0.49038289556657 bayes_pls_golite062009
  • myosin binding
    		•  0.31501932970343 bayes_pls_golite062009
  • catalytic activity
    		•  0.296484721581333 bayes_pls_golite062009
  • transferase activity
    		•  0.105619024604158 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.101675282305395 bayes_pls_golite062009
  • unfolded protein binding
    		•  0.0304569608189402 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle