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Protein Overview: CLEC4M

General Information:
Name(s) found: CLEC4M [HGNC (HUGO)]
Description(s) found:
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  • gi|47607495|ref|NP_999840.1| C-type lectin domain family 4, member M isoform 1 [Homo sapiens] [NCBI NR]
  • gi|46395990|sp|Q9H2X3.1|CLC4M_HUMAN RecName: Full=C-type lectin domain family 4 member M; AltName: Full=CD209 antigen-like protein 1; AltName: Full=Dendritic cell-specific ICAM-3-grabbing non-integrin 2; Short=DC-SIGN2; AltName: Full=DC-SIGN-related prote [NCBI NR]
  • gi|42542390|ref|NP_055072.3| C-type lectin domain family 4, member M isoform 1 [Homo sapiens] [NCBI NR]
  • gi|24416563|gb|AAH38851.1| C-type lectin domain family 4, member M [Homo sapiens] [NCBI NR]
  • gi|15383606|gb|AAK91859.1| mDC-SIGN2 type I isoform [Homo sapiens] [NCBI NR]
  • gi|12084795|gb|AAG13815.2| probable mannose binding C-type lectin DC-SIGNR [Homo sapiens] [NCBI NR]
  • C-type lectin domain family 4, member M [HGNC (HUGO)]
  • C-type lectin domain family 4 member M OS=Homo sapiens GN=CLEC4M PE=1 SV=1 [Swiss-Prot]
  • (Q9H2X3) CD209 antigen-like protein 1 (Dendritic cell-specific ICAM-3-grabbing nonintegrin 2) (DC-SIGN2) (DC-SIGN related protein) (DC-SIGNR) (Liver/lymph node-specific ICAM-3-grabbing nonintegrin) (L-SIGN) [Swiss-Prot]
  • Probable mannose binding C-type lectin DC-SIGNR [hmr_yeast5_DM3-1_pombe.fasta]
  • CD209 antigen-like; putative type II membrane protein [HMR_022704.fasta]
  • CD209 antigen-like isoform 1; probable mannose binding C-type lectin DC-SIGNR; dendritic cell-specific ICAM-3-grabbing nonintegrin 2; type II membrane protein similar to HIV gp120-binding C-type lectin [071204_hmrz_cont.fasta]
  • CD209 antigen-like isoform 1 [Homo sapiens]gi|42542390|ref|NP_055072.3| CD209 antigen-like isoform 1 [Homo sapiens]gi|24416563|gb|AAH38851.1| CD209 antigen-like, isoform 1 [Homo sapiens]gi|15383606|gb|AAK91859.1| mDC-SIGN2 type I isoform [Homo sapiens] [nrdb_11152004_Chlamydomonas]
  • CD209 antigen-like protein 1 (Dendritic cell-specific ICAM-3-grabbing nonintegrin 2) (DC-SIGN2) (DC-SIGN-related protein) (DC-SIGNR) (Liver/lymph node-specific ICAM-3-grabbing nonintegrin) (L-SIGN) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Splice Isoform 1 of C-type lectin domain family 4 member M [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • C-type lectin domain family 4, member M isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 Splice Isoform 1 of CD209 antigen-like protein 1 [EBI-IPI_human_3.12_11-03-2005_con_reversed.fasta]
  • CD209 antigen-like isoform 1; probable mannose binding C-type lectin DC-SIGNR; dendritic cell-specific ICAM-3-grabbing nonintegrin 2; type II membrane protein similar to HIV gp120-binding C-type lectin [Homo sapiens] [HumanGallus06162005.fasta]
  • CD299 antigen isoform 1 [Homo sapiens] [human-contam-plus-rand.fasta]
  • CD209 antigen-like; putative type II membrane protein [Homo sapiens] [human-NCBI-042104-rand.fasta]
  • C-type lectin domain family 4 member M (CD209 antigen-like protein 1) (Dendritic cell-specific ICAM-3-grabbing non-integrin 2) (DC-SIGN2) (DC-SIGN-related protein) (DC-SIGNR) (Liver/lymph node-specific ICAM-3-grabbing non-integrin) (L-SIGN) (CD299 antigen [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • C-type lectin domain family 4, member M [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • probable mannose binding C-type lectin DC-SIGNR [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • mDC-SIGN2 type I isoform [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Isoform 1 of C-type lectin domain family 4 member M [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 SPLICE ISOFORM 1 OF CD209 ANTIGEN-LIKE PROTEIN 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • RecName: Full=C-type lectin domain family 4 member M; AltName: Full=CD209 antigen-like protein 1; AltName: Full=Dendritic cell-specific ICAM-3-grabbing non-integrin 2; Short=DC-SIGN2; AltName: Full=DC-SIGN-related protein; Short=DC-SIGNR; AltName: Full=Li [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=CLEC4M Isoform 1 of C-type lectin domain family 4 member M [human-ipi-250309-contam.fasta]
  • C-type lectin domain family 4 member M (CD209 antigen-like protein 1) (Dendritic cell-specific ICAM-3-grabbing nonintegrin 2) (DC-SIGN2) (DC-SIGN-related protein) (DC-SIGNR) (Liver/lymph node-specific ICAM-3-grabbing nonintegrin) (L-SIGN) (CD299 antigen) [nr-271106-contam.fasta]
  • IPI:IPI00385903.1|SWISS-PROT:Q9H2X3-1|TREMBL:Q2TB20|ENSEMBL:ENSP00000316228|REFSEQ:NP_055072|VEGA:OTTHUMP00000076216 Tax_Id=9606 Gene_Symbol=CLEC4M Isoform 1 of C-type lectin domain family 4 member M [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=CLEC4M Isoform 1 of C-type lectin domain family 4 member M ENSG00000104938 IPI00748018 IPI00290003 IPI00385903 IPI00003402 IPI00410005 IPI00642143 IPI00409772 IPI00746323 IPI00410004 IPI00382671 IPI00156091 IPI00410009 IPI00465229 [drosphohumanreversed.fasta]
  • C-type lectin domain family 4 member M isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Q9H2X3;A6NKI4;A8K8B3;Q69F40;Q969M4;Q96QP3;Q96QP4;Q96QP5;Q96QP6;Q9BXS3;Q9H2Q9;Q9H8F0;Q9Y2A8; RecName: Full=C-type lectin domain family 4 member M; AltName: Full=CD209 antigen-like protein 1; AltName: Full=Dendritic cell-specific ICAM-3-grabbing non-integrin 2; AltName: Full=DC-SIGN-related protein; AltName: Full=Liver/lymph node-specific ICAM-3-grabbing non-integrin; AltName: CD_antigen=CD299; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Isoform 1 of C-type lectin domain family 4 member M OS=Homo sapiens GN=CLEC4M [011711_HMR.fasta]
  • GeneSymbol=CLEC4M Synonyms=CD209L|CD299|DC-SIGN2|DC-SIGNR|DCSIGNR|HP10347|L-SIGN|LSIGN|MGC129964|MGC47866 C-type lectin domain family 4 member M isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00385903.1|SWISS-PROT:Q9H2X3-1|ENSEMBL:ENSP00000316228|REFSEQ:NP_055072 Tax_Id=9606 Gene_Symbol=CLEC4M Isoform 1 of C-type lectin domain family 4 member M [ipi.HUMAN.20110912.fasta]
  • C-type lectin domain family 4 member M GN=CLEC4M [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 399 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDSKEPRVQ QLGLLEEDPT TSGIRLFPRD FQFQQIHGHK SSTGCLGHGA LVLQLLSFML  60
   61 LAGVLVAILV QVSKVPSSLS QEQSEQDAIY QNLTQLKAAV GELSEKSKLQ EIYQELTQLK 120
  121 AAVGELPEKS KLQEIYQELT RLKAAVGELP EKSKLQEIYQ ELTRLKAAVG ELPEKSKLQE 180
  181 IYQELTRLKA AVGELPEKSK LQEIYQELTE LKAAVGELPE KSKLQEIYQE LTQLKAAVGE 240
  241 LPDQSKQQQI YQELTDLKTA FERLCRHCPK DWTFFQGNCY FMSNSQRNWH DSVTACQEVR 300
  301 AQLVVIKTAE EQNFLQLQTS RSNRFSWMGL SDLNQEGTWQ WVDGSPLSPS FQRYWNSGEP 360
  361 NNSGNEDCAE FSGSGWNDNR CDVDNYWICK KPAACFRDE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..172] PSI-BLAST 18.221849 No description for 2o6qA was found.
    2 View Details [173..262] deduced N/A Confident ab initio structure predictions are available.
    3 View Details [263..399] PSI-BLAST 26.09691 Crystal Structure of a fragment of DC-SIGNR (containg the carbohydrate recognition domain and two repeats of the neck) complexed with Lewis-x.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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