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Protein Overview: Set2-PB

General Information:
Name(s) found: Set2-PB / FBpp0290774 [FlyBase]
Description(s) found:
Found 15 descriptions.
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  • The gene Set2 is referred to in FlyBase by the symbol Dmel\Set2 (CG1716, FBgn0030486). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:13307311..13315057. It has the cytological map location 11F4-11F5. There is experimental evidence that it has the molecular function</span>: histone methyltransferase activity (H3-K36 specific); phosphoprotein binding. There is experimental evidence that it is involved in the biological process</span>: ecdysone receptor-mediated signaling pathway; instar larval development; wing disc development; histone H3-K36 methylation. 5 alleles are reported. The phenotype of these alleles is annotated with: wing. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 2313 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    Biological Process: wing disc development [IMP]
    ecdysone receptor-mediated signaling pathway [IGI]
    histone methylation [ISS]
    histone H3-K36 methylation [IMP]
    instar larval development [IMP]
    Molecular Function: DNA binding [IEA]
    transcription cofactor activity [ISS]
    histone-lysine N-methyltransferase activity [ISS]
    histone methyltransferase activity (H3-K36 specific) [IMP]
    phosphoprotein binding [IPI]
    transcription factor binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEESGPPSNP SPVASRGRGR GRPPKVALSA LGNTPPHINP SLKHADAEAS PTAPEDQDSG  60
   61 QSECRRSSRK KIIKFDVRDL LNKNRKAHKI QIEARIDSNP STGHSQSGTT AASTSMSTAT 120
  121 ASAASASSAA TVSRLFSMFE MSHQSLPPPP PPPTALEIFA KPRPTQSLIV AQVTSEPSAV 180
  181 GGAHPVQTMA GLPPVTPRKR GRPRKSQLAD AAIIPTVIVP SCSDSDTNST STTTSNMSSD 240
  241 SGELPGFPIQ KPKSKLRVSL KRLKLGGRLE SSDSGNSPSS SSPEVEPPAL QDENAMDERP 300
  301 KQEQNLSRMV DAEENSDSDS QIIFIEIETE SPKGEEEQEE GRPVEVEPQD LIDIDMELAK 360
  361 QEPTPDPEED LDEIMVEVLS GPPSLWSADD EAEEEEDATV QRATPPGKEP AADSCSSAPR 420
  421 RSRRSAPLSG SSRQGKTLEE TFAEIAAESS KQILEAEESQ DQEEQHILID LIEDTLKSDN 480
  481 IAASLNKDIF EPKVETKATC GEVVPRPEMV TEDVYITEGI AATLEKSAVV TKPTTEMIAE 540
  541 TKLSDEVVIE PPLKDESDPK QTEVELPESK PAVNIPKSER ILSAEVETTS SPLVPPECCT 600
  601 LESVSGPVLL ETSLSTEEKS NENVETTPLK TEAAKEDSPP AAPEEEASNS SEEPNFLLED 660
  661 YESNQEQVAE DEMMKCNNQK GQKQTPLPEM KEPEKPVAET VSKKEKAMEN PARSSPAIVD 720
  721 KKVRAGEMEK KVVKSTKGTV PEKKMDSKKS CAAVTPAKQK ESGKSAKEAI LKKETEKEKS 780
  781 SAKLDSSSPN TLDKKGKDTA QWSPQLQTLP KSSTKPPQES APSVISKTTS NQPAPKEEQH 840
  841 AAKKGLSDNS PPSVLKAKEK AVSGFVECDA MFKAMDLANA QLRLDEKNKK KLKKVPTKVE 900
  901 APPKVEPPTA VPVPGQKKSL SGKTSLRRNT VYEDSPNLER NSSPSSDSAQ ANTSAGKLKP 960
  961 SKVKKKINPR RSTICEAAKD LRSSSSSSTP TREVAASSPV STSSDSSSKR NGSKRTTSDL1020
 1021 DGGSKLDQRR YTICEDRQPE TAIPVPLTKR RFSMHPKASA NPLHDTLLQT AGKKRGRKEG1080
 1081 KESLSRQNSL DSSSSASQGA PKKKALKSAE ILSAALLETE SSESTSSGSK MSRWDVQTSP1140
 1141 ELEAANPFGD IAKFIEDGVN LLKRDKVDED QRKEGQDEVK READPEEDEF AQRVANMETP1200
 1201 ATTPTPSPTQ SNPEDSASTT TVLKELETGG GVRRSHRIKQ KPQGPRASQG RGVASVALAP1260
 1261 ISMDEQLAEL ANIEAINEQF LRSEGLNTFQ LLKENFYRCA RQVSQENAEM QCDCFLTGDE1320
 1321 EAQGHLSCGA GCINRMLMIE CGPLCSNGAR CTNKRFQQHQ CWPCRVFRTE KKGCGITAEL1380
 1381 LIPPGEFIME YVGEVIDSEE FERRQHLYSK DRNRHYYFMA LRGEAVIDAT SKGNISRYIN1440
 1441 HSCDPNAETQ KWTVNGELRI GFFSVKPIQP GEEITFDYQY LRYGRDAQRC YCEAANCRGW1500
 1501 IGGEPDSDEG EQLDEESDSD AEMDEEELEA EPEEGQPRKS AKAKAKSKLK AKLPLATGRK1560
 1561 RKEQTKPKDR EYKAGRWLKP SATGSSSSAE KPPKKPKVNK FQAMLEDPDV VEELSLLRRG1620
 1621 GLKNQQDTLR FSRCLVRAKL LKTRLALLRV LTHGELPCRR LFLDYHGLRL LHAWISENGN1680
 1681 DDQLREALLD TLESLPIPNR TMLSDSRVYQ SVQLWSNSLE QQLAVVPQEK QAALHKRMVA1740
 1741 LLQKWQALPE IFRIPKRERI EQMKEHEREA DRQQKHVHAS TALEDQRERE SSNDRFRQDR1800
 1801 FRRDTTSSRI GKPIRMSGNN TICTITTQQK GSNGAPDGMT RNDNRRRSDI GPPSEQRRTL1860
 1861 SKELRRSLFE RKVALDEAER RVCTEDRLEH ELRCEFFGAD INTDPKQLPF YQKTDTNEWF1920
 1921 NSDDVPVPAP PRTELLTKAL LSPDIDVGQG ATDVEYKLPP GVDPLPPAWN WQVTSDGDIY1980
 1981 YYNLRERISQ WEPPSPEQRL QTLLEENTTQ QPLHELQIDP AVLENELIQV DTDYVGSLSA2040
 2041 KSLAQYIEAK VRERRDLRRS KLVSIRLISP RRDEDRLYNQ LESRKYKENK EKIRRRKELY2100
 2101 RRRKIEVLPD AVDEIPVPGK ALPIQPYLFS SDEEETKVAA IEQPAAEEEQ DSLNMAPSTS2160
 2161 HAAMAALGKA VAQPTGLGTV GKRKLPMPPS VTVKKHRQEQ RSKKVKSSQS PLTATSAREA2220
 2221 HEKFRFEISG HVANFLRPYR KESCTLGRIT SDEDYKFLVN RLSYHITTKE MRYCEVSGNP2280
 2281 LSCTESVKHK SYDFINQYMR QKGPVYKKPA END

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle