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Protein Overview: CAPNS1

General Information:
Name(s) found: CAPNS1 [HGNC (HUGO)]
Description(s) found:
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  • pir||CIHUL calpain (EC 3.4.22.17) small chain - human [NCBI NR]
  • gi|54781355|gb|AAV40829.1| calpain, small subunit 1 [Homo sapiens] [NCBI NR]
  • gi|51599151|ref|NP_001003962.1| calpain, small subunit 1 [Homo sapiens] [NCBI NR]
  • gi|4502565|ref|NP_001740.1| calpain, small subunit 1 [Homo sapiens] [NCBI NR]
  • gi|40226191|gb|AAH23643.1| Calpain, small subunit 1 [Homo sapiens] [NCBI NR]
  • gi|35328|emb|CAA27726.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|32879893|gb|AAP88777.1| calpain, small subunit 1 [Homo sapiens] [NCBI NR]
  • gi|2443873|gb|AAB81546.1| CANS_Human [Homo sapiens] [NCBI NR]
  • gi|1905903|gb|AAB51183.1| calcium-dependent protease, small (regulatory) subunit (calpain) (calcium-activated neutral proteinase) (CANP) [Homo sapiens] [NCBI NR]
  • gi|179909|gb|AAA35646.1| neutral protease alpha subunit [NCBI NR]
  • gi|17511950|gb|AAH18931.1| Calpain, small subunit 1 [Homo sapiens] [NCBI NR]
  • gi|16878212|gb|AAH17308.1| Calpain, small subunit 1 [Homo sapiens] [NCBI NR]
  • gi|158260235|dbj|BAF82295.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|14043606|gb|AAH07779.1| Calpain, small subunit 1 [Homo sapiens] [NCBI NR]
  • gi|12653629|gb|AAH00592.1| Calpain, small subunit 1 [Homo sapiens] [NCBI NR]
  • gi|115612|sp|P04632.1|CPNS1_HUMAN RecName: Full=Calpain small subunit 1; Short=CSS1; AltName: Full=Calcium-dependent protease small subunit 1; AltName: Full=Calcium-dependent protease small subunit; Short=CDPS; AltName: Full=Calpain regulatory subunit; Al [NCBI NR]
  • calpain, small subunit 1 [HGNC (HUGO)]
  • (P04632) Calpain small subunit 1 (CSS1) (Calcium-dependent protease small subunit 1) (Calcium-dependent protease small subunit) (CDPS) (Calpain regulatory subunit) (Calcium-activated neutral proteinase small subunit) (CANP small subunit) [Swiss-Prot]
  • Calpain small subunit 1 OS=Homo sapiens GN=CAPNS1 PE=1 SV=1 [Swiss-Prot]
  • Calcium-dependent protease, small subunit [hmr_yeast5_DM3-1_pombe.fasta]
  • calpain, small subunit 1; calpain, small polypeptide; calcium-dependent protease, small subunit; calcium-activated neutral proteinase; calpain 4, small subunit (30K) [HMR_022704.fasta]
  • calpain, small subunit 1; calcium-activated neutral proteinase; calpain, small polypeptide; calpain 4, small subunit (30K); calcium-dependent protease, small subunit [Human2242005.fasta]
  • calpain, small subunit 1 [Homo sapiens]gi|4502565|ref|NP_001740.1| calpain, small subunit 1 [Homo sapiens]gi|51599151|ref|NP_001003962.1| calpain, small subunit 1 [Homo sapiens]gi|32879893|gb|AAP88777.1| calpain, small subunit 1 [Homo sapiens]gi|17511 [nrdb_11152004_Chlamydomonas]
  • Calpain small subunit 1 (CSS1) (Calcium-dependent protease small subunit 1) (Calcium-dependent protease small subunit) (CDPS) (Calpain regulatory subunit) (Calcium-activated neutral proteinase small subunit) (CANP small subunit) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Calpain small subunit 1 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_001749) calpain, small subunit 1; calpain, small polypeptide; calcium-dependent protease, small subunit; calcium-activated neutral proteinase; calpain 4, small subunit (30K) [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • calpain, small subunit 1 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • calpain, small subunit 1; calcium-activated neutral proteinase; calpain, small polypeptide; calpain 4, small subunit (30K); calcium-dependent protease, small subunit [Homo sapiens] [HumanGallus06162005.fasta]
  • calpain, small subunit 1; calpain, small polypeptide; calcium-dependent protease, small subunit; calcium-activated neutral proteinase; calpain 4, small subunit (30K) [Homo sapiens] [human-NCBI-042104-rand.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Calpain, small subunit 1 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • calcium-dependent protease, small (regulatory) subunit (calpain) (calcium-activated neutral proteinase) (CANP) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • CANS_Human [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • neutral protease alpha subunit [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 CALPAIN SMALL SUBUNIT 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • RecName: Full=Calpain small subunit 1; Short=CSS1; AltName: Full=Calcium-dependent protease small subunit 1; AltName: Full=Calcium-dependent protease small subunit; Short=CDPS; AltName: Full=Calpain regulatory subunit; AltName: Full=Calcium-activated neut [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=CAPNS1 Calpain small subunit 1 [human-ipi-250309-contam.fasta]
  • IPI:IPI00025084.3|SWISS-PROT:P04632|ENSEMBL:ENSP00000246533;ENSP00000400882|REFSEQ:NP_001003962;NP_001740|H-INV:HIT000321011|VEGA:OTTHUMP00000076192;OTTHUMP00000076193 Tax_Id=9606 Gene_Symbol=CAPNS1 Calpain small subunit 1 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • P04632;A8K0P1;Q8WTX3;Q96EW0; RecName: Full=Calpain small subunit 1; AltName: Full=Calcium-dependent protease small subunit 1; AltName: Full=Calcium-dependent protease small subunit; AltName: Full=Calpain regulatory subunit; AltName: Full=Calcium-activated neutral proteinase small subunit; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Calpain small subunit 1 OS=Homo sapiens GN=CAPNS1 [011711_HMR.fasta]
  • GeneSymbol=CAPNS1 Synonyms=30K|CALPAIN4|CANP|CANPS|CAPN4|CDPS|CSS1 calpain small subunit 1 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00025084.3|SWISS-PROT:P04632|ENSEMBL:ENSP00000246533|REFSEQ:NP_001003962;NP_001740|H-INV:HIT000321011 Tax_Id=9606 Gene_Symbol=CAPNS1 Calpain small subunit 1 [ipi.HUMAN.20110912.fasta]
  • Calpain small subunit 1 GN=CAPNS1 [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 268 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFLVNSFLKG GGGGGGGGGG LGGGLGNVLG GLISGAGGGG GGGGGGGGGG GGGGGGTAMR  60
   61 ILGGVISAIS EAAAQYNPEP PPPRTHYSNI EANESEEVRQ FRRLFAQLAG DDMEVSATEL 120
  121 MNILNKVVTR HPDLKTDGFG IDTCRSMVAV MDSDTTGKLG FEEFKYLWNN IKRWQAIYKQ 180
  181 FDTDRSGTIC SSELPGAFEA AGFHLNEHLY NMIIRRYSDE SGNMDFDNFI SCLVRLDAMF 240
  241 RAFKSLDKDG TGQIQVNIQE WLQLTMYS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run DAD1 Dam1-765 complex purified from yeast with Dad1-TAP Shimogawa MM, et al. (2006)
    View Run DAD1 Dam1-765 complex purified from yeast with Dad1-TAP Shimogawa MM, et al. (2006)
    View Run DAD1 Dam1 complex purified from yeast with Dad1-TAP Shimogawa MM, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..176] PSI-BLAST 5.39794 Crystal Structure of the Catalytic Domain of Atypical Protein Kinase C-iota
    2 View Details [177..268] PSI-BLAST 26.69897 Crystal Structure of a mu-like calpain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle