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Protein Overview: NSFL1C

General Information:
Name(s) found: NSFL1C [HGNC (HUGO)]
Description(s) found:
Found 32 descriptions.
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  • NSFL1 (p97) cofactor (p47) [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 370 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAERQEALR EFVAVTGAEE DRARFFLESA GWDLQIALAS FYEDGGDEDI VTISQATPSS  60
   61 VSRGTAPSDN RVTSFRDLIH DQDEDEEEEE GQRFYAGGSE RSGQQIVGPP RKKSPNELVD 120
  121 DLFKGAKEHG AVAVERVTKS PGETSKPRPF AGGGYRLGAA PEEESAYVAG EKRQHSSQDV 180
  181 HVVLKLWKSG FSLDNGELRS YQDPSNAQFL ESIRRGEVPA ELRRLAHGGQ VNLDMEDHRD 240
  241 EDFVKPKGAF KAFTGEGQKL GSTAPQVLST SSPAQQAENE AKASSSILID ESEPTTNIQI 300
  301 RLADGGRLVQ KFNHSHRISD IRLFIVDARP AMAATSFILM TTFPNKELAD ESQTLKEANL 360
  361 LNAVIVQRLT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..68] MSA 12.070996 View MSA. No confident structure predictions are available.
    2 View Details [69..160] deduced N/A No confident structure predictions are available.
    3 View Details [161..271] PSI-BLAST 20.69897 Solution structure of SEP domain from human p47
    4 View Details [272..370] PSI-BLAST 35.69897 Crystal structure of AAA ATPase p97/VCP ND1 in complex with p47 C

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • binding
    		•  1.73741203922834 bayes_pls_golite062009
  • protein binding
    		•  1.6357717410164 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  1.16524840930815 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  0.544811416739 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.288560953468985 bayes_pls_golite062009
  • hydrolase activity
    		•  0.0740461973842489 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle