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Protein Overview: ADARB2

General Information:
Name(s) found: ADARB2 [HGNC (HUGO)]
Description(s) found:
Found 30 descriptions.
SHOW ALL
  • adenosine deaminase, RNA-specific, B2 (RED2 homolog rat) [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 739 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASVLGSGRG SGGLSSQLKC KSKRRRRRRS KRKDKVSILS TFLAPFKHLS PGITNTEDDD  60
   61 TLSTSSAEVK ENRNVGNLAA RPPPSGDRAR GGAPGAKRKR PLEEGNGGHL CKLQLVWKKL 120
  121 SWSVAPKNAL VQLHELRPGL QYRTVSQTGP VHAPVFAVAV EVNGLTFEGT GPTKKKAKMR 180
  181 AAELALRSFV QFPNACQAHL AMGGGPGPGT DFTSDQADFP DTLFQEFEPP APRPGLAGGR 240
  241 PGDAALLSAA YGRRRLLCRA LDLVGPTPAT PAAPGERNPV VLLNRLRAGL RYVCLAEPAE 300
  301 RRARSFVMAV SVDGRTFEGS GRSKKLARGQ AAQAALQELF DIQMPGHAPG RARRTPMPQE 360
  361 FADSISQLVT QKFREVTTDL TPMHARHKAL AGIVMTKGLD ARQAQVVALS SGTKCISGEH 420
  421 LSDQGLVVND CHAEVVARRA FLHFLYTQLE LHLSKRREDS ERSIFVRLKE GGYRLRENIL 480
  481 FHLYVSTSPC GDARLHSPYE ITTDLHSSKH LVRKFRGHLR TKIESGEGTV PVRGPSAVQT 540
  541 WDGVLLGEQL ITMSCTDKIA RWNVLGLQGA LLSHFVEPVY LQSIVVGSLH HTGHLARVMS 600
  601 HRMEGVGQLP ASYRHNRPLL SGVSDAEARQ PGKSPPFSMN WVVGSADLEI INATTGRRSC 660
  661 GGPSRLCKHV LSARWARLYG RLSTRTPSPG DTPSMYCEAK LGAHTYQSVK QQLFKAFQKA 720
  721 GLGTWVRKPP EQQQFLLTL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..122] deduced N/A No confident structure predictions are available.
    2 View Details [123..196] PSI-BLAST 18.39794 No description for 2b7tA was found.
    3 View Details [197..352] PSI-BLAST 18.154902 No description for 2b7vA was found.
    4 View Details [353..739] PSI-BLAST 161.0 Crystal structure of the catalytic domain of an adenosine deaminase that acts on RNA (hADAR2) bound to inositol hexakisphosphate (IHP)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • double-stranded RNA adenosine deaminase activity
    		•  5.04262574612905 bayes_pls_golite062009
  • RNA binding
    		•  4.18713691832357 bayes_pls_golite062009
  • binding
    		•  3.09705138687537 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.95361490759242 bayes_pls_golite062009
  • DNA binding
    		•  1.51133867432475 bayes_pls_golite062009
  • double-stranded RNA binding
    		•  1.46317494664076 bayes_pls_golite062009
  • protein binding
    		•  1.33336414936007 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.33042413200827 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.25950932467779 bayes_pls_golite062009
  • structural molecule activity
    		•  1.17628321323282 bayes_pls_golite062009
  • transcription factor activity
    		•  0.42419387757895 bayes_pls_golite062009
  • protein kinase activity
    		•  0.174129357494585 bayes_pls_golite062009
  • mRNA binding
    		•  0.158440222485456 bayes_pls_golite062009
    3
    Term Confidence Notes
  • double-stranded RNA adenosine deaminase activity
    		•  5.04262574612905 bayes_pls_golite062009
  • RNA binding
    		•  4.18713691832357 bayes_pls_golite062009
  • binding
    		•  3.09705138687537 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.95361490759242 bayes_pls_golite062009
  • DNA binding
    		•  1.51133867432475 bayes_pls_golite062009
  • double-stranded RNA binding
    		•  1.46317494664076 bayes_pls_golite062009
  • protein binding
    		•  1.33336414936007 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.33042413200827 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.25950932467779 bayes_pls_golite062009
  • structural molecule activity
    		•  1.17628321323282 bayes_pls_golite062009
  • transcription factor activity
    		•  0.42419387757895 bayes_pls_golite062009
  • protein kinase activity
    		•  0.174129357494585 bayes_pls_golite062009
  • mRNA binding
    		•  0.158440222485456 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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