Protein Overview: TUBB4

General Information:
Name(s) found:	TUBB4 [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|93141323\|sp\|P04350.2\|TBB4_HUMAN RecName: Full=Tubulin beta-4 chain; AltName: Full=Tubulin 5 beta [NCBI NR] gi\|21361322\|ref\|NP_006078.2\| tubulin, beta 4 [Homo sapiens] [NCBI NR] gi\|193786783\|dbj\|BAG52106.1\| unnamed protein product [Homo sapiens] [NCBI NR] gi\|16306901\|gb\|AAH06570.1\| TUBB4 protein [Homo sapiens] [NCBI NR] gi\|15489150\|gb\|AAH13683.1\| Tubulin, beta 4 [Homo sapiens] [NCBI NR] gi\|119589484\|gb\|EAW69078.1\| tubulin, beta 4, isoform CRA_a [Homo sapiens] [NCBI NR] tubulin, beta 4 [HGNC (HUGO)] Tubulin beta-4 chain OS=Homo sapiens GN=TUBB4 PE=1 SV=2 [Swiss-Prot] Tubulin beta-4A chain OS=Homo sapiens GN=TUBB4A PE=1 SV=2 [Swiss-Prot] Hypothetical protein [hmr_yeast5_DM3-1_pombe.fasta] tubulin, beta, 5 [HMR_022704.fasta] TUBB5 protein [Homo sapiens]gi\|31981939\|ref\|NP_033477.2\| tubulin, beta 4 [Mus musculus]gi\|21361322\|ref\|NP_006078.2\| tubulin, beta, 5 [Homo sapiens]gi\|29145006\|gb\|AAH49112.1\| Tubulin, beta 4 [Mus musculus]gi\|32766247\|gb\|AAH54831.1\| Tubulin, beta 4 [Mus [nrdb_11152004_Chlamydomonas] Tax_Id=9606 Tubulin beta-4 chain [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta] (NM_006087) tubulin, beta, 5 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] tubulin, beta 4 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta] Tax_Id=9606 Tubulin, beta 4 [EBI-IPI_human_3.12_11-03-2005_con_reversed.fasta] tubulin, beta, 5 [Homo sapiens] [HumanGallus06162005.fasta] Tax_Id=9606 Hypothetical protein [EBI-IPI_Drosophila_na_12-13-2007_con_reversed.fasta] unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tubulin beta-4 chain (Tubulin 5 beta) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] tubulin, beta 4, isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tubulin, beta 4 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] TUBB4 protein [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tax_Id=9606 TUBULIN, BETA, 5 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=9606 Gene_Symbol=TUBB4 Tubulin beta-4 chain [human-ipi-250309-contam.fasta] IPI:IPI00023598.2\|SWISS-PROT:P04350\|TREMBL:B3KQP4;B4DE77\|ENSEMBL:ENSP00000264071\|REFSEQ:NP_006078\|H-INV:HIT000036323\|VEGA:OTTHUMP00000078206 Tax_Id=9606 Gene_Symbol=TUBB4 Tubulin beta-4 chain [ipi.HUMAN.fasta.20090807] [human_BMb_040710_contam.fasta] Tax_Id=9606 Gene_Symbol=TUBB4 Tubulin beta-4 chain ENSG00000104833 IPI00023598 [drosphohumanreversed.fasta] P04350;B3KQP4;Q969E5; RecName: Full=Tubulin beta-4 chain; AltName: Full=Tubulin 5 beta; [UniProt_Human_2010_06_06-01-2010_reversed.fasta] Tubulin beta-4 chain OS=Homo sapiens GN=TUBB4 [011711_HMR.fasta] IPI:IPI00023598.2\|SWISS-PROT:P04350\|TREMBL:B4DE77\|ENSEMBL:ENSP00000264071\|REFSEQ:NP_006078\|H-INV:HIT000036323\|VEGA:OTTHUMP00000078206 Tax_Id=9606 Gene_Symbol=TUBB4 Tubulin beta-4 chain [ipi.HUMAN.fasta.20100406] Tubulin beta-4 chain n=122 Tax=Fungi/Metazoa group RepID=TBB4_HUMAN [UniProt_Xenopus_laevis_01-01-2011_reversed.fasta] GeneSymbol=TUBB4 Synonyms=TUBB5\|beta-5 tubulin beta-4 chain [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] IPI:IPI00023598.2\|SWISS-PROT:P04350\|TREMBL:B4DE77\|ENSEMBL:ENSP00000264071;ENSP00000443590\|REFSEQ:NP_006078\|H-INV:HIT000036323 Tax_Id=9606 Gene_Symbol=TUBB4 Tubulin beta-4 chain [ipi.HUMAN.20110912.fasta] Tubulin beta-4A chain GN=TUBB4A [Doctor+uniprot-HUMAN-120911.fasta]
Organism:	Homo sapiens
Length:	444 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MREIVHLQAG QCGNQIGAKF WEVISDEHGI DPTGTYHGDS DLQLERINVY YNEATGGNYV  60
   61 PRAVLVDLEP GTMDSVRSGP FGQIFRPDNF VFGQSGAGNN WAKGHYTEGA ELVDAVLDVV 120
  121 RKEAESCDCL QGFQLTHSLG GGTGSGMGTL LISKIREEFP DRIMNTFSVV PSPKVSDTVV 180
  181 EPYNATLSVH QLVENTDETY CIDNEALYDI CFRTLKLTTP TYGDLNHLVS ATMSGVTTCL 240
  241 RFPGQLNADL RKLAVNMVPF PRLHFFMPGF APLTSRGSQQ YRALTVPELT QQMFDAKNMM 300
  301 AACDPRHGRY LTVAAVFRGR MSMKEVDEQM LSVQSKNSSY FVEWIPNNVK TAVCDIPPRG 360
  361 LKMAATFIGN STAIQELFKR ISEQFTAMFR RKAFLHWYTG EGMDEMEFTE AESNMNDLVS 420
  421 EYQQYQDATA EEGEFEEEAE EEVA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	None Entered	Sample pIC145 from april 2005	Okada, M., et al. (2006)
View Run	None Entered	Sample pIC146 from april 2005	Okada, M., et al. (2006)
View Run	gi\|14317902, gi\|...	No Comments	Cheeseman, I.M., et al. (2004)
View Run	MIS12	No Comments	Cheeseman, I.M., et al. (2004)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..444]	PSI-BLAST	1000.0	Tubulin:stathmin-like domain complex

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: TUBB4

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: