YRC Public Data Repository - Protein Structure Prediction

Protein:	TUBB4
Organism:	Homo sapiens
Length:	444 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TUBB4.

Description	E-value	Query Range	Subject Range
TBA1C_MOUSE - Tubulin alpha-1C chain OS=Mus musculus GN=Tuba1c PE=1 SV=1 gi\|124481732, gi... - gi\|148225011\|ref\|NP_001091315.1\| hypothetical protein LOC100037141 [Xenopus laevis], gi\|124481732\|gb... TBA1C_CRIGR - Tubulin alpha-1C chain OS=Cricetulus griseus GN=TUBA1C PE=2 SV=1	0.0	[1..438]	[1..448]
gi\|73996516 - gi\|73996516\|ref\|XP_850665.1\| PREDICTED: similar to Tubulin alpha-2 chain (Alpha-tubulin 2) isoform 2...	0.0	[1..438]	[1..448]
gi\|67463741, gi\|... - gi\|67463743\|pdb\|1Z2B\|C Chain C, Tubulin-Colchicine-Vinblastine: Stathmin-Like Domain Complex, gi\|674...	0.0	[1..438]	[1..448]
TBA1C_RAT - Tubulin alpha-1C chain OS=Rattus norvegicus GN=Tuba1c PE=1 SV=1	0.0	[1..438]	[1..448]
TBA_XENLA - Tubulin alpha chain OS=Xenopus laevis GN=tuba PE=2 SV=2	0.0	[1..438]	[1..448]
gi\|115960583, gi... - gi\|72057626\|ref\|XP_780117.1\| PREDICTED: similar to tubulin, alpha 2 isoform 1 [Strongylocentrotus pu...	0.0	[1..439]	[1..449]
gi\|114644941 - gi\|114644941\|ref\|XP_001158840.1\| PREDICTED: tubulin alpha 6 isoform 1 [Pan troglodytes] gi\|123990474, gi... - gi\|123999316\|gb\|ABM87234.1\| tubulin, alpha 6 [synthetic construct], gi\|123990474\|gb\|ABM83912.1\| tubu... TUBA1C - tubulin, alpha 1c	0.0	[1..438]	[1..448]
gi\|60653689 - gi\|60653689\|gb\|AAX29538.1\| tubulin alpha 6 [synthetic construct]	0.0	[1..438]	[1..448]

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Predicted Domain #1

Region A:
Residues: [1-444]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MREIVHLQAG QCGNQIGAKF WEVISDEHGI DPTGTYHGDS DLQLERINVY YNEATGGNYV  60
   61 PRAVLVDLEP GTMDSVRSGP FGQIFRPDNF VFGQSGAGNN WAKGHYTEGA ELVDAVLDVV 120
  121 RKEAESCDCL QGFQLTHSLG GGTGSGMGTL LISKIREEFP DRIMNTFSVV PSPKVSDTVV 180
  181 EPYNATLSVH QLVENTDETY CIDNEALYDI CFRTLKLTTP TYGDLNHLVS ATMSGVTTCL 240
  241 RFPGQLNADL RKLAVNMVPF PRLHFFMPGF APLTSRGSQQ YRALTVPELT QQMFDAKNMM 300
  301 AACDPRHGRY LTVAAVFRGR MSMKEVDEQM LSVQSKNSSY FVEWIPNNVK TAVCDIPPRG 360
  361 LKMAATFIGN STAIQELFKR ISEQFTAMFR RKAFLHWYTG EGMDEMEFTE AESNMNDLVS 420
  421 EYQQYQDATA EEGEFEEEAE EEVA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1ffxB
Description:	Tubulin:stathmin-like domain complex
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits