Protein Overview: ec-PC

General Information:
Name(s) found:	ec-PC / FBpp0111714 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|89574412\|gb\|ABD77422.1\| echinus splice form 3 [Drosophila melanogaster] [NCBI NR] gi\|161077554\|ref\|NP_001096877.1\| echinus, isoform C [Drosophila melanogaster] [NCBI NR] gi\|158031712\|gb\|ABW09333.1\| echinus, isoform C [Drosophila melanogaster] [NCBI NR] The gene echinus is referred to in FlyBase by the symbol Dmel\ec (CG2904, FBgn0000542). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3705976..3751658. It has the cytological map location 3F2-3F3. It is reported to have molecular function</span>: ubiquitin thiolesterase activity. There is experimental evidence that it is involved in the biological process</span>: compound eye morphogenesis. 40 alleles are reported. The phenotypes of these alleles are annotated with: eye; adult thorax; dorsocentral bristle; primary pigment cell; adult abdomen; posterior notopleural bristle; cone cell; wing; ommatidium. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase] type=protein; loc=X:join(3744316..3744744,3744996..3745289,3745970..3746098,3746173..3750618); ID=FBpp0111714; name=ec-PC; parent=FBgn0000542,FBtr0112802; dbxref=FlyBase:FBpp0111714,FlyBase_Annotation_IDs:CG2904-PC,REFSEQ:NP_001096877,GB_protein:ABW09333; [fly-100309-contam.fasta] echinus splice form 3 [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=X:join(3744316..3744744,3744996..3745289,3745970..3746098,3746173..3750618); ID=FBpp0111714; name=ec-PC; parent=FBgn0000542,FBtr0112802; dbxref=FlyBase:FBpp0111714,FlyBase_Annotation_IDs:CG2904-PC,REFSEQ:NP_001096877,GB_protein:ABW09333; MD5=f6e15f7a5a911a7d499cf9f19388f298; length=1765; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=X:join(3744316..3744744,3744996..3745289,3745970..3746098,3746173..3750618); ID=FBpp0111714; name=ec-PC; parent=FBgn0000542,FBtr0112802; dbxref=FlyBase:FBpp0111714,FlyBase_Annotation_IDs:CG2904-PC,REFSEQ:NP_001096877,GB_protein:ABW09333; MD5=f6e15f7a5a911a7d499cf9f19388f298; length=1765; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Echinus splice form 3 OS=Drosophila melanogaster GN=ec PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=X:join(3744316..3744744,3744996..3745289,3745970..3746098,3746173..3750618); ID=FBpp0111714; name=ec-PC; parent=FBgn0000542,FBtr0112802; dbxref=FlyBase:FBpp0111714,FlyBase_Annotation_IDs:CG2904-PC,REFSEQ:NP_001096877,GB_protein:ABW09333,FlyMine:FBpp0111714,modMine:FBpp0111714; MD5=f6e15f7a5a911a7d499cf9f19388f298; length=1765; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=X:join(3850283..3850711,3850963..3851256,3851937..3852065,3852140..3856585); ID=FBpp0111714; name=ec-PC; parent=FBgn0000542,FBtr0112802; dbxref=FlyBase:FBpp0111714,FlyBase_Annotation_IDs:CG2904-PC,REFSEQ:NP_001096877,GB_protein:ABW09333,FlyMine:FBpp0111714,modMine:FBpp0111714; MD5=f6e15f7a5a911a7d499cf9f19388f298; length=1765; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=X:join(3850283..3850711,3850963..3851256,3851937..3852065,3852140..3856585); ID=FBpp0111714; name=ec-PC; parent=FBgn0000542,FBtr0112802; dbxref=FlyBase:FBpp0111714,FlyBase_Annotation_IDs:CG2904-PC,REFSEQ:NP_001096877,GB_protein:ABW09333,FlyMine:FBpp0111714,modMine:FBpp0111714; MD5=f6e15f7a5a911a7d499cf9f19388f298; length=1765; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0111714 type=protein; loc=X:join(3850283..3850711,3850963..3851256,3851937..3852065,3852140..3856585); ID=FBpp0111714; name=ec-PC; parent=FBgn0000542,FBtr0112802; dbxref=FlyBase:FBpp0111714,FlyBase_Annotation_IDs:CG2904-PC,REFSEQ:NP_001096877,GB_protein:ABW09333,FlyMine:FBpp0111714,modMine:FBpp0111714; MD5=f6e15f7a5a911a7d499cf9f19388f298; length=1765; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=X:join(3850283..3850711,3850963..3851256,3851937..3852065,3852140..3856585); ID=FBpp0111714; name=ec-PC; parent=FBgn0000542,FBtr0112802; dbxref=FlyBase:FBpp0111714,FlyBase_Annotation_IDs:CG2904-PC,REFSEQ:NP_001096877,GB_protein:ABW09333,UniProt/TrEMBL:Q1W9P9,FlyMine:FBpp0111714,modMine:FBpp0111714; MD5=f6e15f7a5a911a7d499cf9f19388f298; length=1765; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	1765 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	[NOT]protein deubiquitination [IDA] compound eye morphogenesis [IMP] retinal cell programmed cell death [TAS] compound eye retinal cell programmed cell death [TAS] ubiquitin-dependent protein catabolic process [IEA]
Molecular Function:	[NOT]ubiquitin-specific protease activity [IDA] ubiquitin thiolesterase activity [IEA][NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIKFRYKRKE PTNVVGVAAP TAGAAALGSG ASSTPGTSPT SPVSVPVPVQ AHHPHPQLGH  60
   61 LISNNGGTLP RSSPRKLILD GADKSATLTR QQSKQKSVSA LAKVASSVEL AVMGYNSTGN 120
  121 GNSNGHINSA GNSERDRCIN AVIELFQQLQ TSSEPALCPE PLRRALASGP LAGRRFPLGC 180
  181 LGDAAECFEL LLHRVHSHIS PDDGDSCESS ACIAHRRFAM RVIEQSVCKC GANSEQLPFT 240
  241 QMVHYVSASA LTSQKSLALQ SHQQLSFGQL LRAAGNMGDI RDCPNTCGAK IGICRALLNR 300
  301 PEVVSIGIVW DSERPAADQV HAVLKAVGTS LRLGDVFHQV SEPRWAQQTQ HELVGIVSYY 360
  361 GKHYTTFFFH TKLKVWVYFD DANVKEVGPS WEGVVDKCSR GRYQPLLLLY AVPQQPTVGN 420
  421 GVGIGHVDVA MPASAPSIAG SVVRRAVTPS PEKPSLGNTR RAITPTPLRT PPNDYQNLSV 480
  481 IQKNIFPSNL AMGTDETDAY ISRKTVEHVL SAQYQNLSVI QDKIGGGNGV GVGQQSVDKD 540
  541 GGFLSRKPIE AVLSAQLARR QHLQLQRSHS AESSSGHASS NGSSPPSDGL TMPEHLNQPR 600
  601 RRDSGNWSGD RNSASSASST TLDNPYLYMV AKRGVAAVPQ SPTRHGLPYD PGYDSFSLSS 660
  661 TDSYPPKHAL NPQLAKIPEA AMGVVPNGGA MPHGHGNGQL ALSGDCEKLC HEADQLLEKS 720
  721 RLVEESHDLE TALVLCNAAA GRARAAMDAP YSNPHTMTFA RMKHNTCVMR ARSLHRRILV 780
  781 EKGAETEAMP ELKHMREGST SSVKHVRQNS KDRTLEKEQQ QLQFQQIQQI QQIHQIQQQI 840
  841 PASIEIYATL PKRKSPLKAL ASASACDDNA IEYEQEKQLA TSPGKPERES RSLFGRKDKE 900
  901 KEKRSRSEDR NKLTREFSLT ETLLVNAKDT LKKHKEDKDE KKEKDKSGKK QHKIRRKLLM 960
  961 GGLIRRKNRS MPDLTEAVDD STANAGITHH PHYPAQGVTT AGTLLGTSVD DSAVGLGKHG1020
 1021 HGMSGYISEG HFDYSGSGSA SNSGAGSNPN PNLERSKLMR KSFHGSGRQL TMVPKVAPPP1080
 1081 PMRTSSTLTP QQQQQQQQQF HHEANLSNLS AMSSNTSISE DSCQTIITTC AQVHSEQSPL1140
 1141 KDLQMLVAQD ELPLPPPMEL PPYPSPPHSS CHSRQASEDF PPPPPPELDL EPLNQQLSQL1200
 1201 QALEAASKQQ RQQLESLEGT TSILAQLQQR QHLLKLRKEQ ANHPGAATTD ATWLKELQAK1260
 1261 QANDLRAMQR KLEASSPSSV RDLTHRFEQT SIRSYASQEL LSQPGQSQQL GQLRTQMNGL1320
 1321 PNGNAKMDVD EVDAMPAVRN SLPAALSAHQ LLPKPKYEMT QSQIAEEIRE VELLNTMVQQ1380
 1381 TLNQNGAAAL PKRVKKKSVS FCDQVILVAT AGNEEDDDFI PNPILERVLR TAQHPNEKVT1440
 1441 AQMIQQQQQN MMRLQTEAQP RQQQVQQLQQ PSPMLGRPAG ATADMQRYVQ RMQQQQQQQQ1500
 1501 QQQQQQQQQQ QQQQQQQQQQ QQQQQQHQEL YRQQQLHRTS MSGIASQQHL QQLDAQYTTM1560
 1561 PRPLHHSQLG SYSVTLQKHQ QLQQQQQQQQ QQQAPQQLSL GYFSNGSVAT SEQVPLPSPY1620
 1621 QRVPLPHGYQ PAAAGPYYPL PNAQQHLQQQ QLMAKPVQKK VSFEPGTKGE ADCLPPPPPP1680
 1681 PQKNGLPETG SAGSGHPGAA PGASGAGGTT SAGITAIPTR VYNNAIVKAS AKAVECNLCR1740
 1741 KRHVIAPAVY CTNCEYYLQM LNQRR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: ec-PC

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: