Protein Overview: ec-PB

General Information:
Name(s) found:	ec-PB / FBpp0111713 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|89574410\|gb\|ABD77421.1\| echinus splice form 1 [Drosophila melanogaster] [NCBI NR] gi\|161077552\|ref\|NP_570078.2\| echinus, isoform B [Drosophila melanogaster] [NCBI NR] gi\|158031711\|gb\|AAN09109.2\| echinus, isoform B [Drosophila melanogaster] [NCBI NR] The gene echinus is referred to in FlyBase by the symbol Dmel\ec (CG2904, FBgn0000542). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3705976..3751658. It has the cytological map location 3F2-3F3. It is reported to have molecular function</span>: ubiquitin thiolesterase activity. There is experimental evidence that it is involved in the biological process</span>: compound eye morphogenesis. 40 alleles are reported. The phenotypes of these alleles are annotated with: eye; adult thorax; dorsocentral bristle; primary pigment cell; adult abdomen; posterior notopleural bristle; cone cell; wing; ommatidium. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase] type=protein; loc=X:join(3714770..3715048,3735357..3735449,3744996..3745289,3745970..3746098,3746173..3750618); ID=FBpp0111713; name=ec-PB; parent=FBgn0000542,FBtr0112801; dbxref=FlyBase:FBpp0111713,FlyBase_Annotation_IDs:CG2904-PB,REFSEQ:NP_570078,GB_pro [fly-100309-contam.fasta] echinus splice form 1 [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=X:join(3714770..3715048,3735357..3735449,3744996..3745289,3745970..3746098,3746173..3750618); ID=FBpp0111713; name=ec-PB; parent=FBgn0000542,FBtr0112801; dbxref=FlyBase:FBpp0111713,FlyBase_Annotation_IDs:CG2904-PB,REFSEQ:NP_570078,GB_protein:AAN09109; MD5=d986cf02506e09e51f52edee0f0f3840; length=1746; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=X:join(3714770..3715048,3735357..3735449,3744996..3745289,3745970..3746098,3746173..3750618); ID=FBpp0111713; name=ec-PB; parent=FBgn0000542,FBtr0112801; dbxref=FlyBase:FBpp0111713,FlyBase_Annotation_IDs:CG2904-PB,REFSEQ:NP_570078,GB_protein:AAN09109; MD5=d986cf02506e09e51f52edee0f0f3840; length=1746; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Echinus splice form 1 OS=Drosophila melanogaster GN=ec PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=X:join(3714770..3715048,3735357..3735449,3744996..3745289,3745970..3746098,3746173..3750618); ID=FBpp0111713; name=ec-PB; parent=FBgn0000542,FBtr0112801; dbxref=FlyBase:FBpp0111713,FlyBase_Annotation_IDs:CG2904-PB,REFSEQ:NP_570078,GB_protein:AAN09109,FlyMine:FBpp0111713,modMine:FBpp0111713; MD5=d986cf02506e09e51f52edee0f0f3840; length=1746; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=X:join(3820737..3821015,3841324..3841416,3850963..3851256,3851937..3852065,3852140..3856585); ID=FBpp0111713; name=ec-PB; parent=FBgn0000542,FBtr0112801; dbxref=FlyBase:FBpp0111713,FlyBase_Annotation_IDs:CG2904-PB,REFSEQ:NP_570078,GB_protein:AAN09109,FlyMine:FBpp0111713,modMine:FBpp0111713; MD5=d986cf02506e09e51f52edee0f0f3840; length=1746; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=X:join(3820737..3821015,3841324..3841416,3850963..3851256,3851937..3852065,3852140..3856585); ID=FBpp0111713; name=ec-PB; parent=FBgn0000542,FBtr0112801; dbxref=FlyBase:FBpp0111713,FlyBase_Annotation_IDs:CG2904-PB,REFSEQ:NP_570078,GB_protein:AAN09109,FlyMine:FBpp0111713,modMine:FBpp0111713; MD5=d986cf02506e09e51f52edee0f0f3840; length=1746; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Isoform of Q1W9P9, Echinus splice form 1 OS=Drosophila melanogaster GN=ec PE=2 SV=1 [DROME.fasta.20160308] FBpp0111713 type=protein; loc=X:join(3820737..3821015,3841324..3841416,3850963..3851256,3851937..3852065,3852140..3856585); ID=FBpp0111713; name=ec-PB; parent=FBgn0000542,FBtr0112801; dbxref=FlyBase:FBpp0111713,FlyBase_Annotation_IDs:CG2904-PB,REFSEQ:NP_570078,GB_protein:AAN09109,FlyMine:FBpp0111713,modMine:FBpp0111713; MD5=d986cf02506e09e51f52edee0f0f3840; length=1746; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=X:join(3820737..3821015,3841324..3841416,3850963..3851256,3851937..3852065,3852140..3856585); ID=FBpp0111713; name=ec-PB; parent=FBgn0000542,FBtr0112801; dbxref=FlyBase:FBpp0111713,FlyBase_Annotation_IDs:CG2904-PB,REFSEQ:NP_570078,GB_protein:AAN09109,UniProt/TrEMBL:Q1W9Q0,FlyMine:FBpp0111713,modMine:FBpp0111713; MD5=d986cf02506e09e51f52edee0f0f3840; length=1746; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	1746 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	[NOT]protein deubiquitination [IDA] compound eye morphogenesis [IMP] retinal cell programmed cell death [TAS] compound eye retinal cell programmed cell death [TAS] ubiquitin-dependent protein catabolic process [IEA]
Molecular Function:	[NOT]ubiquitin-specific protease activity [IDA] ubiquitin thiolesterase activity [IEA][NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAHSGRRMT TPGTLYRLAS GSAATPATPT NSPYGQPAKP YAVGSIQNGS ERNRILELLR  60
   61 APNSLTSPTL EPSSKGLLNG PGQNNCFLNC AVQVLWHLDA FRRSFRGLNQ HVCGGQDCIF 120
  121 CALKELFQQL QTSSEPALCP EPLRRALASG PLAGRRFPLG CLGDAAECFE LLLHRVHSHI 180
  181 SPDDGDSCES SACIAHRRFA MRVIEQSVCK CGANSEQLPF TQMVHYVSAS ALTSQKSLAL 240
  241 QSHQQLSFGQ LLRAAGNMGD IRDCPNTCGA KIGICRALLN RPEVVSIGIV WDSERPAADQ 300
  301 VHAVLKAVGT SLRLGDVFHQ VSEPRWAQQT QHELVGIVSY YGKHYTTFFF HTKLKVWVYF 360
  361 DDANVKEVGP SWEGVVDKCS RGRYQPLLLL YAVPQQPTVG NGVGIGHVDV AMPASAPSIA 420
  421 GSVVRRAVTP SPEKPSLGNT RRAITPTPLR TPPNDYQNLS VIQKNIFPSN LAMGTDETDA 480
  481 YISRKTVEHV LSAQYQNLSV IQDKIGGGNG VGVGQQSVDK DGGFLSRKPI EAVLSAQLAR 540
  541 RQHLQLQRSH SAESSSGHAS SNGSSPPSDG LTMPEHLNQP RRRDSGNWSG DRNSASSASS 600
  601 TTLDNPYLYM VAKRGVAAVP QSPTRHGLPY DPGYDSFSLS STDSYPPKHA LNPQLAKIPE 660
  661 AAMGVVPNGG AMPHGHGNGQ LALSGDCEKL CHEADQLLEK SRLVEESHDL ETALVLCNAA 720
  721 AGRARAAMDA PYSNPHTMTF ARMKHNTCVM RARSLHRRIL VEKGAETEAM PELKHMREGS 780
  781 TSSVKHVRQN SKDRTLEKEQ QQLQFQQIQQ IQQIHQIQQQ IPASIEIYAT LPKRKSPLKA 840
  841 LASASACDDN AIEYEQEKQL ATSPGKPERE SRSLFGRKDK EKEKRSRSED RNKLTREFSL 900
  901 TETLLVNAKD TLKKHKEDKD EKKEKDKSGK KQHKIRRKLL MGGLIRRKNR SMPDLTEAVD 960
  961 DSTANAGITH HPHYPAQGVT TAGTLLGTSV DDSAVGLGKH GHGMSGYISE GHFDYSGSGS1020
 1021 ASNSGAGSNP NPNLERSKLM RKSFHGSGRQ LTMVPKVAPP PPMRTSSTLT PQQQQQQQQQ1080
 1081 FHHEANLSNL SAMSSNTSIS EDSCQTIITT CAQVHSEQSP LKDLQMLVAQ DELPLPPPME1140
 1141 LPPYPSPPHS SCHSRQASED FPPPPPPELD LEPLNQQLSQ LQALEAASKQ QRQQLESLEG1200
 1201 TTSILAQLQQ RQHLLKLRKE QANHPGAATT DATWLKELQA KQANDLRAMQ RKLEASSPSS1260
 1261 VRDLTHRFEQ TSIRSYASQE LLSQPGQSQQ LGQLRTQMNG LPNGNAKMDV DEVDAMPAVR1320
 1321 NSLPAALSAH QLLPKPKYEM TQSQIAEEIR EVELLNTMVQ QTLNQNGAAA LPKRVKKKSV1380
 1381 SFCDQVILVA TAGNEEDDDF IPNPILERVL RTAQHPNEKV TAQMIQQQQQ NMMRLQTEAQ1440
 1441 PRQQQVQQLQ QPSPMLGRPA GATADMQRYV QRMQQQQQQQ QQQQQQQQQQ QQQQQQQQQQ1500
 1501 QQQQQQQHQE LYRQQQLHRT SMSGIASQQH LQQLDAQYTT MPRPLHHSQL GSYSVTLQKH1560
 1561 QQLQQQQQQQ QQQQAPQQLS LGYFSNGSVA TSEQVPLPSP YQRVPLPHGY QPAAAGPYYP1620
 1621 LPNAQQHLQQ QQLMAKPVQK KVSFEPGTKG EADCLPPPPP PPQKNGLPET GSAGSGHPGA1680
 1681 APGASGAGGT TSAGITAIPT RVYNNAIVKA SAKAVECNLC RKRHVIAPAV YCTNCEYYLQ1740
 1741 MLNQRR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.52

Protein Overview: ec-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: