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Protein Overview: TK1

General Information:
Name(s) found: TK1 [HGNC (HUGO)]
Description(s) found:
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  • gi|52632392|gb|AAH06484.1| Thymidine kinase 1, soluble [Homo sapiens] [NCBI NR]
  • gi|30582721|gb|AAP35587.1| thymidine kinase 1, soluble [Homo sapiens] [NCBI NR]
  • gi|23503074|sp|P04183.2|KITH_HUMAN RecName: Full=Thymidine kinase, cytosolic [NCBI NR]
  • gi|189067473|dbj|BAG37455.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|164698438|ref|NP_003249.3| thymidine kinase 1 [Homo sapiens] [NCBI NR]
  • gi|14124928|gb|AAH07986.1| TK1 protein [Homo sapiens] [NCBI NR]
  • gi|14043853|gb|AAH07872.1| Thymidine kinase 1, soluble [Homo sapiens] [NCBI NR]
  • thymidine kinase 1, soluble [HGNC (HUGO)]
  • Thymidine kinase, cytosolic OS=Homo sapiens GN=TK1 PE=1 SV=2 [Swiss-Prot]
  • Thymidine kinase, cytosolic [hmr_yeast5_DM3-1_pombe.fasta]
  • TK1 protein [Homo sapiens]gi|52632392|gb|AAH06484.1| Thymidine kinase 1, soluble [Homo sapiens]gi|30582721|gb|AAP35587.1| thymidine kinase 1, soluble [Homo sapiens]gi|14043853|gb|AAH07872.1| Thymidine kinase 1, soluble [Homo sapiens]gi|23503074|sp|P04 [nrdb_11152004_Chlamydomonas]
  • Tax_Id=9606 Thymidine kinase, cytosolic [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • Thymidine kinase 1, soluble [Homo sapiens] [NCBI-RefSeq_human_na_05-03-2007_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • thymidine kinase 1, soluble [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • TK1 protein [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 THYMIDINE KINASE, CYTOSOLIC [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • RecName: Full=Thymidine kinase, cytosolic [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=TK1 Thymidine kinase, cytosolic [human-ipi-250309-contam.fasta]
  • thymidine kinase 1 [Homo sapiens] [NCBI-RefSeq_human_na_07-13-2009_con_reversed.fasta]
  • IPI:IPI00299214.7|SWISS-PROT:P04183|TREMBL:B5BU32;B5BUF9|ENSEMBL:ENSP00000301634;ENSP00000384981|REFSEQ:NP_003249|H-INV:HIT000273434|VEGA:OTTHUMP00000182525;OTTHUMP00000182526;OTTHUMP00000198229 Tax_Id=9606 Gene_Symbol=TK1 Thymidine kinase, cytosolic [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • thymidine kinase, cytosolic [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • P04183;B2RC58;Q969V0;Q9UMG9; RecName: Full=Thymidine kinase, cytosolic; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Thymidine kinase, cytosolic OS=Homo sapiens GN=TK1 [011711_HMR.fasta]
  • GeneSymbol=TK1 Synonyms=TK2 thymidine kinase, cytosolic [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00299214.7|SWISS-PROT:P04183|TREMBL:B5BU32;B5BUF9|ENSEMBL:ENSP00000301634;ENSP00000384981|REFSEQ:NP_003249|H-INV:HIT000273434|VEGA:OTTHUMP00000198229 Tax_Id=9606 Gene_Symbol=TK1 Thymidine kinase, cytosolic [ipi.HUMAN.20110912.fasta]
  • Thymidine kinase, cytosolic GN=TK1 [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 234 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSCINLPTVL PGSPSKTRGQ IQVILGPMFS GKSTELMRRV RRFQIAQYKC LVIKYAKDTR  60
   61 YSSSFCTHDR NTMEALPACL LRDVAQEALG VAVIGIDEGQ FFPDIVEFCE AMANAGKTVI 120
  121 VAALDGTFQR KPFGAILNLV PLAESVVKLT AVCMECFREA AYTKRLGTEK EVEVIGGADK 180
  181 YHSVCRLCYF KKASGQPAGP DNKENCPVPG KPGEAVAARK LFAPQQILQC SPAN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..234] PSI-BLAST 105.0 No description for 2orvA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nucleobase, nucleoside, nucleotide kinase activity
    		•  3.66392587433723 bayes_pls_golite062009
  • nucleotide kinase activity
    		•  2.24094813695083 bayes_pls_golite062009
  • kinase activity
    		•  2.0779386406753 bayes_pls_golite062009
  • phosphotransferase activity, phosphate group as acceptor
    		•  1.96697952975573 bayes_pls_golite062009
  • binding
    		•  1.57531761895117 bayes_pls_golite062009
  • DNA binding
    		•  1.22619720972604 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.17199530230795 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.16376707327858 bayes_pls_golite062009
  • transcription factor activity
    		•  0.472763834470731 bayes_pls_golite062009
  • protein binding
    		•  0.456164256440374 bayes_pls_golite062009
  • adenylate kinase activity
    		•  0.447752711852745 bayes_pls_golite062009
  • hydrolase activity
    		•  0.420858111948277 bayes_pls_golite062009
  • catalytic activity
    		•  0.101795606736461 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle