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Protein Overview: C1QA

General Information:
Name(s) found: C1QA [HGNC (HUGO)]
Description(s) found:
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  • gi|7705753|ref|NP_057075.1| complement component 1, q subcomponent, A chain precursor [Homo sapiens] [NCBI NR]
  • gi|56205031|emb|CAI22893.1| complement component 1, q subcomponent, A chain [Homo sapiens] [NCBI NR]
  • gi|54781353|gb|AAV40828.1| complement component 1, q subcomponent, alpha polypeptide [Homo sapiens] [NCBI NR]
  • gi|4894854|gb|AAD32626.1|AF135157_1 complement C1q A chain precursor [Homo sapiens] [NCBI NR]
  • gi|48734785|gb|AAH71986.1| Complement component 1, q subcomponent, A chain [Homo sapiens] [NCBI NR]
  • gi|399138|sp|P02745.2|C1QA_HUMAN RecName: Full=Complement C1q subcomponent subunit A; Flags: Precursor [NCBI NR]
  • pir||C1HUQA complement subcomponent C1q chain A precursor [validated] - human [NCBI NR]
  • gi|20988805|gb|AAH30153.1| Complement component 1, q subcomponent, A chain [Homo sapiens] [NCBI NR]
  • gi|189065196|dbj|BAG34919.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|119615421|gb|EAW95015.1| complement component 1, q subcomponent, A chain, isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119615420|gb|EAW95014.1| complement component 1, q subcomponent, A chain, isoform CRA_a [Homo sapiens] [NCBI NR]
  • complement component 1, q subcomponent, A chain [HGNC (HUGO)]
  • Complement C1q subcomponent subunit A OS=Homo sapiens GN=C1QA PE=1 SV=2 [Swiss-Prot]
  • Complement C1q subcomponent, A chain precursor [hmr_yeast5_DM3-1_pombe.fasta]
  • complement component 1, q subcomponent, alpha polypeptide precursor; complement component C1q, A chain [HMR_022704.fasta]
  • complement component 1, q subcomponent, alpha polypeptide [Homo sapiens]gi|7705753|ref|NP_057075.1| complement component 1, q subcomponent, alpha polypeptide precursor [Homo sapiens]gi|48734785|gb|AAH71986.1| Complement component 1, q subcomponent, alph [nrdb_11152004_Chlamydomonas]
  • Tax_Id=9606 Complement C1q subcomponent subunit A precursor [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_015991) complement component 1, q subcomponent, alpha polypeptide precursor; complement C1q A chain precursor,; complement component C1q, A chain [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • complement component 1, q subcomponent, A chain precursor [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 Complement C1q subcomponent, A chain precursor [EBI-IPI_human_3.12_11-03-2005_con_reversed.fasta]
  • complement component 1, q subcomponent, alpha polypeptide precursor; complement component C1q, A chain [Homo sapiens] [HumanGallus06162005.fasta]
  • Complement C1q subcomponent subunit A precursor [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • complement component 1, q subcomponent, A chain [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • complement component 1, q subcomponent, A chain, isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Complement component 1, q subcomponent, A chain [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • complement component 1, q subcomponent, alpha polypeptide [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • complement C1q A chain precursor [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 COMPLEMENT C1Q SUBCOMPONENT, A CHAIN PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=C1QA Complement C1q subcomponent subunit A [human-ipi-250309-contam.fasta]
  • IPI:IPI00022392.1|SWISS-PROT:P02745|TREMBL:B2R4X2|ENSEMBL:ENSP00000363773;ENSP00000385564|REFSEQ:NP_057075|H-INV:HIT000040965|VEGA:OTTHUMP00000002936;OTTHUMP00000197085 Tax_Id=9606 Gene_Symbol=C1QA Complement C1q subcomponent subunit A [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=C1QA Complement C1q subcomponent subunit A precursor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • complement C1q subcomponent subunit A precursor [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • P02745;B2R4X2;Q5T963; RecName: Full=Complement C1q subcomponent subunit A; Flags: Precursor; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Complement C1q subcomponent subunit A OS=Homo sapiens GN=C1QA [011711_HMR.fasta]
  • IPI:IPI00022392.1|SWISS-PROT:P02745|ENSEMBL:ENSP00000363773;ENSP00000385564|REFSEQ:NP_057075|H-INV:HIT000040965|VEGA:OTTHUMP00000002936;OTTHUMP00000197085 Tax_Id=9606 Gene_Symbol=C1QA Complement C1q subcomponent subunit A [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=C1QA Synonyms=- complement C1q subcomponent subunit A precursor [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • Complement C1q subcomponent subunit A GN=C1QA [Doctor+uniprot-HUMAN-120911.fasta]
  • Complement component 1, q subcomponent, A chain, isoform CRA_a OS=Homo sapiens GN=C1QA PE=4 SV=1 [uniprot-human-031015-contam.fasta]
    • Organism: Homo sapiens
    Length: 245 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEGPRGWLVL CVLAISLASM VTEDLCRAPD GKKGEAGRPG RRGRPGLKGE QGEPGAPGIR  60
   61 TGIQGLKGDQ GEPGPSGNPG KVGYPGPSGP LGARGIPGIK GTKGSPGNIK DQPRPAFSAI 120
  121 RRNPPMGGNV VIFDTVITNQ EEPYQNHSGR FVCTVPGYYY FTFQVLSQWE ICLSIVSSSR 180
  181 GQVRRSLGFC DTTNKGLFQV VSGGMVLQLQ QGDQVWVEKD PKKGHIYQGS EADSVFSGFL 240
  241 IFPSA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..168] PSI-BLAST 14.0 No description for 1y0fB was found.
    2 View Details [169..245] PSI-BLAST 26.0 Globular Head of the Complement System Protein C1q

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • tumor necrosis factor receptor superfamily binding
    		•  3.27382150819697 bayes_pls_golite062009
  • receptor binding
    		•  2.87092342030082 bayes_pls_golite062009
  • cytokine activity
    		•  2.15273244126886 bayes_pls_golite062009
  • binding
    		•  1.56262702810355 bayes_pls_golite062009
  • cell surface binding
    		•  1.12145675554147 bayes_pls_golite062009
  • protein binding
    		•  1.103851389575 bayes_pls_golite062009
  • tumor necrosis factor receptor binding
    		•  0.83659914028185 bayes_pls_golite062009
  • CD40 receptor binding
    		•  0.817940383456736 bayes_pls_golite062009
  • eukaryotic cell surface binding
    		•  0.3981620493951 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle