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View Structure Prediction Details

Protein: C1QA
Organism: Homo sapiens
Length: 245 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for C1QA.

Description E-value Query
Range
Subject
Range
gi|50731037 - gi|50731037|ref|XP_417136.1| PREDICTED: similar to Mitochondrial intermediate peptidase [Gallus gall...
1.0E-42 [2..241] [82..323]
gi|61368776, gi|... - gi|61368781|gb|AAX43236.1| complement component 1 q subcomponent alpha polypeptide [synthetic constr...
1.0E-35 [1..245] [1..245]
gi|114554611 - gi|114554611|ref|XP_001166821.1| PREDICTED: complement component 1, q subcomponent, A chain [Pan tro...
1.0E-35 [1..245] [1..245]
C1QA_RAT - Complement C1q subcomponent subunit A OS=Rattus norvegicus GN=C1qa PE=1 SV=2
1.0E-35 [1..245] [1..245]
gi|73811113, gi|... - gi|73811113|gb|AAZ86518.1| adiponectin [Sus scrofa], gi|170065991|gb|ACB06567.1| adiponectin [Sus sc...
3.0E-35 [11..242] [24..239]

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Predicted Domain #1
Region A:
Residues: [1-168]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEGPRGWLVL CVLAISLASM VTEDLCRAPD GKKGEAGRPG RRGRPGLKGE QGEPGAPGIR  60
   61 TGIQGLKGDQ GEPGPSGNPG KVGYPGPSGP LGARGIPGIK GTKGSPGNIK DQPRPAFSAI 120
  121 RRNPPMGGNV VIFDTVITNQ EEPYQNHSGR FVCTVPGYYY FTFQVLSQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.0
Match: 1y0fB
Description: No description for 1y0fB was found.

Predicted Domain #2
Region A:
Residues: [169-245]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WEICLSIVSS SRGQVRRSLG FCDTTNKGLF QVVSGGMVLQ LQQGDQVWVE KDPKKGHIYQ  60
   61 GSEADSVFSG FLIFPSA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.0
Match: 1pk6A
Description: Globular Head of the Complement System Protein C1q
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
tumor necrosis factor receptor superfamily binding 3.27382150819697 bayes_pls_golite062009
receptor binding 2.87092342030082 bayes_pls_golite062009
cytokine activity 2.15273244126886 bayes_pls_golite062009
binding 1.56262702810355 bayes_pls_golite062009
cell surface binding 1.12145675554147 bayes_pls_golite062009
protein binding 1.103851389575 bayes_pls_golite062009
tumor necrosis factor receptor binding 0.83659914028185 bayes_pls_golite062009
CD40 receptor binding 0.817940383456736 bayes_pls_golite062009
eukaryotic cell surface binding 0.3981620493951 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle