Protein Overview: agt-1

General Information:
Name(s) found:	agt-1 / CE39872 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00000093 locus:agt-1 status:Confirmed UniProt:Q2HQK2 protein_id:CAJ76952.1 [WormBase] gi\|87251675\|emb\|CAJ76952.1\| C. elegans protein Y62E10A.5b, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|115533070\|ref\|NP_001041055.1\| AlkylGuanine DNA alkylTransferase family member (agt-1) [Caenorhabditis elegans] [NCBI NR] CE39872 WBGene00000093 locus:agt-1 status:Confirmed UniProt:Q2HQK2_CAEEL protein_id:CAJ76952.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE39872 WBGene00000093 locus:agt-1 status:Confirmed UniProt:Q2HQK2_CAEEL protein_id:CAJ76952.1\| [wormORF-contam.fasta] CE39872 WBGene00000093 locus:agt-1 status:Confirmed TR:Q2HQK2 protein_id:CAJ76952.1 [wormpep160-contam.fasta] AlkylGuanine DNA alkylTransferase family member (agt-1) [Caenorhabditis elegans] [nr-271106-contam.fasta] Hypothetical protein Y62E10A.5b [Caenorhabditis elegans] [nr-271106-contam.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE39872 WBGene00000093 locus:agt-1 status:Confirmed UniProt:Q2HQK2 protein_id:CAJ76952.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] Isoform of Q9U1Y0, AlkylGuanine DNA alkylTransferase OS=Caenorhabditis elegans GN=agt-1 PE=1 SV=1 [CAEEL.fasta.20160308]
Organism:	Caenorhabditis elegans
Length:	133 amino acids
Gene Ontology:
Cellular Component:	nucleus [IC]
Biological Process:	DNA dealkylation involved in DNA repair [IDA] DNA repair [IEA]
Molecular Function:	methylated-DNA-[protein]-cysteine S-methyltransferase activity [IEA] damaged DNA binding [IDA] transferase activity, transferring alkyl or aryl (other than methyl) groups [IDA]

Sequence:
Sequence: [PDR BLAST] [ProtParam]	1 11 21 31 41 51 \| \| \| \| \| \| 1 MEELHDAYPT VNFIPGKPTQ SSGIVQALNT LDSTIKVNAV HKGDTAFGMQ VYSAIQKIPK 60 61 GETRSYSDIA REIGNPSAVR AVASACARNN LAYIVPCHRV IGSTGNLSGY RWGIAKKRRL 120 121 LQAEGAELRF SVM

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..133]	PSI-BLAST	34.0	ADA O6-METHYLGUANINE-DNA METHYLTRANSFERASE FROM ESCHERICHIA COLI

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
catalytic activity	1.37832662286977	bayes_pls_golite062009
transferase activity	0.80006734170602	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	0.62706339438363	bayes_pls_golite062009
methyltransferase activity	0.62546749638433	bayes_pls_golite062009
S-methyltransferase activity	0.432092587695091	bayes_pls_golite062009
methylated-DNA-[protein]-cysteine S-methyltransferase activity	0.431084412812689	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle