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Protein Overview: GHRL

General Information:
Name(s) found: GHRL [HGNC (HUGO)]
Description(s) found:
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  • gi|9966513|gb|AAG10300.1|AF296558_1 growth hormone secretagogue precursor [Homo sapiens] [NCBI NR]
  • gi|7706519|ref|NP_057446.1| ghrelin/obestatin isoform 1 preproprotein [Homo sapiens] [NCBI NR]
  • gi|6691919|emb|CAB65733.1| Hm46 protein [Homo sapiens] [NCBI NR]
  • gi|6691572|dbj|BAA89371.1| ghrelin precursor [Homo sapiens] [NCBI NR]
  • gi|37183224|gb|AAQ89412.1| ghrelin [Homo sapiens] [NCBI NR]
  • gi|17865471|sp|Q9UBU3.1|GHRL_HUMAN RecName: Full=Appetite-regulating hormone; AltName: Full=Growth hormone secretagogue; AltName: Full=Growth hormone-releasing peptide; AltName: Full=Motilin-related peptide; AltName: Full=M46 protein; Contains: RecName: F [NCBI NR]
  • gi|157418983|gb|ABV55190.1| ghrelin precursor splice variant [Homo sapiens] [NCBI NR]
  • gi|157418975|gb|ABV55186.1| ghrelin precursor splice variant [Homo sapiens] [NCBI NR]
  • gi|146428558|gb|ABQ40360.1| ghrelin precursor splice variant [Homo sapiens] [NCBI NR]
  • gi|146428556|gb|ABQ40359.1| ghrelin precursor splice variant [Homo sapiens] [NCBI NR]
  • gi|146428554|gb|ABQ40358.1| ghrelin precursor splice variant [Homo sapiens] [NCBI NR]
  • gi|146428551|gb|ABQ40357.1| ghrelin precursor splice variant [Homo sapiens] [NCBI NR]
  • gi|119584479|gb|EAW64075.1| ghrelin, growth hormone secretagogue receptor ligand, isoform CRA_b [Homo sapiens] [NCBI NR]
  • pir||A59316 ghrelin precursor - human [NCBI NR]
  • ghrelin/obestatin prepropeptide [HGNC (HUGO)]
  • Appetite-regulating hormone OS=Homo sapiens GN=GHRL PE=1 SV=1 [Swiss-Prot]
  • Splice isoform 1 of Q9UBU3 [hmr_yeast5_DM3-1_pombe.fasta]
  • ghrelin precursor; motilin-related peptide [HMR_022704.fasta]
  • ghrelin [Homo sapiens]gi|7706519|ref|NP_057446.1| ghrelin precursor [Homo sapiens]gi|6691919|emb|CAB65733.1| Hm46 protein [Homo sapiens]gi|6691572|dbj|BAA89371.1| ghrelin precursor [Homo sapiens]gi|11381445|pir||A59316 ghrelin precursor - humangi|996 [nrdb_11152004_Chlamydomonas]
  • Ghrelin precursor (Growth hormone secretagogue) (Growth hormone releasing peptide) (Motilin-related peptide) (M46 protein) [Contains: Ghrelin-27; Ghrelin-28 (Ghrelin)] [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Splice Isoform 1 of Appetite-regulating hormone precursor [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_016362) ghrelin precursor [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • ghrelin precursor [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 Splice Isoform 1 of Ghrelin precursor [EBI-IPI_human_3.12_11-03-2005_con_reversed.fasta]
  • ghrelin precursor; motilin-related peptide [Homo sapiens] [HumanGallus06162005.fasta]
  • Appetite-regulating hormone precursor (Growth hormone secretagogue) (Growth hormone-releasing peptide) (Motilin-related peptide) (M46 protein) [Contains: Ghrelin-27; Ghrelin-28 (Ghrelin); Obestatin] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • ghrelin precursor splice variant [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • ghrelin, growth hormone secretagogue receptor ligand, isoform CRA_b [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • ghrelin [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Hm46 protein [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • growth hormone secretagogue precursor [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Isoform 1 of Appetite-regulating hormone precursor [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 SPLICE ISOFORM 1 OF GHRELIN PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • ghrelin/obestatin isoform 1 preproprotein [Homo sapiens] [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • RecName: Full=Appetite-regulating hormone; AltName: Full=Growth hormone secretagogue; AltName: Full=Growth hormone-releasing peptide; AltName: Full=Motilin-related peptide; AltName: Full=M46 protein; Contains: RecName: Full=Ghrelin-27; Contains: RecName: [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=GHRL Isoform 1 of Appetite-regulating hormone [human-ipi-250309-contam.fasta]
  • IPI:IPI00008925.3|SWISS-PROT:Q9UBU3-1|TREMBL:A8CF34|ENSEMBL:ENSP00000335074;ENSP00000389192;ENSP00000391406;ENSP00000414819;ENSP00000415521|REFSEQ:NP_057446|H-INV:HIT000253097|VEGA:OTTHUMP00000170220;OTTHUMP00000207790;OTTHUMP00000207794;OTTHUMP0000020779 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=GHRL Isoform 1 of Appetite-regulating hormone precursor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • appetite-regulating hormone isoform 1 preproprotein [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Q9UBU3;Q8TAT9;Q9H3R3; RecName: Full=Appetite-regulating hormone; AltName: Full=Growth hormone secretagogue; AltName: Full=Growth hormone-releasing peptide; AltName: Full=Motilin-related peptide; AltName: Full=Protein M46; Contains: RecName: Full=Ghrelin-27; Contains: RecName: Full=Ghrelin-28; Contains: RecName: Full=Obestatin; Flags: Precursor; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Isoform 1 of Appetite-regulating hormone OS=Homo sapiens GN=GHRL [011711_HMR.fasta]
  • IPI:IPI00008925.3|SWISS-PROT:Q9UBU3-1|TREMBL:A8CF34|ENSEMBL:ENSP00000335074;ENSP00000389192;ENSP00000391406;ENSP00000414819;ENSP00000415521|REFSEQ:NP_057446|H-INV:HIT000253097|VEGA:OTTHUMP00000170220;OTTHUMP00000207790;OTTHUMP00000207794;OTTHUMP00000207796;OTTHUMP00000207798 Tax_Id=9606 Gene_Symbol=GHRL Isoform 1 of Appetite-regulating hormone [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=GHRL Synonyms=MTLRP appetite-regulating hormone isoform 1 preproprotein [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00008925.3|SWISS-PROT:Q9UBU3-1|ENSEMBL:ENSP00000335074;ENSP00000389192;ENSP00000391406;ENSP00000414819|REFSEQ:NP_057446|H-INV:HIT000253097|VEGA:OTTHUMP00000207790;OTTHUMP00000207794;OTTHUMP00000207798 Tax_Id=9606 Gene_Symbol=GHRL Isoform 1 of Appetite-regulating hormone [ipi.HUMAN.20110912.fasta]
  • Appetite-regulating hormone GN=GHRL [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 117 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSPGTVCSL LLLGMLWLDL AMAGSSFLSP EHQRVQQRKE SKKPPAKLQP RALAGWLRPE  60
   61 DGGQAEGAED ELEVRFNAPF DVGIKLSGVQ YQQHSQALGK FLQDILWEEA KEAPADK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..62] MSA 4.026997 View MSA. No confident structure predictions are available.
    2 View Details [63..117] Pfam 30.552842 No description for PF04643.3 was found. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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