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Protein Overview: DAND5

General Information:
Name(s) found: DAND5 [HGNC (HUGO)]
Description(s) found:
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  • gi|75517922|gb|AAI01801.1| Dante, precursor [Homo sapiens] [NCBI NR]
  • gi|74729571|sp|Q8N907.1|DAND5_HUMAN RecName: Full=DAN domain family member 5; AltName: Full=Cerberus-like protein 2; Short=Cerl-2; AltName: Full=Gremlin-3; AltName: Full=Cysteine knot superfamily 1, BMP antagonist 3; Flags: Precursor [NCBI NR]
  • gi|34330117|dbj|BAC82440.1| cysteine knot protein [Homo sapiens] [NCBI NR]
  • gi|22749329|ref|NP_689867.1| dante precursor [Homo sapiens] [NCBI NR]
  • gi|21755284|dbj|BAC04651.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|109731706|gb|AAI13477.1| DAN domain family, member 5 [Homo sapiens] [NCBI NR]
  • DAN domain family, member 5 [HGNC (HUGO)]
  • DAN domain family member 5 OS=Homo sapiens GN=DAND5 PE=2 SV=1 [Swiss-Prot]
  • Hypothetical protein FLJ38607 [hmr_yeast5_DM3-1_pombe.fasta]
  • hypothetical protein FLJ38607 [HMR_022704.fasta]
  • hypothetical protein FLJ38607 [Homo sapiens]gi|21755284|dbj|BAC04651.1| unnamed protein product [Homo sapiens]gi|34330117|dbj|BAC82440.1| cysteine knot protein [Homo sapiens] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=9606 dante precursor [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • dante precursor [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 Hypothetical protein FLJ38607 [EBI-IPI_human_3.12_11-03-2005_con_reversed.fasta]
  • hypothetical protein FLJ38607 [Homo sapiens] [HumanGallus06162005.fasta]
  • DAN domain family member 5 precursor (Cerberus-like protein 2) (Cerl-2) (Gremlin-3) (Cysteine knot superfamily 1, BMP antagonist 3) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • DAN domain family, member 5 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Dante, precursor [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • cysteine knot protein [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 HYPOTHETICAL PROTEIN FLJ38607 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=DAND5 DAN domain family member 5 [human-ipi-250309-contam.fasta]
  • IPI:IPI00167536.1|SWISS-PROT:Q8N907|ENSEMBL:ENSP00000323155|REFSEQ:NP_689867|H-INV:HIT000020781|VEGA:OTTHUMP00000076679 Tax_Id=9606 Gene_Symbol=DAND5 DAN domain family member 5 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=DAND5 dante precursor ENSG00000179284 IPI00167536 IPI00647045 IPI00719393 [drosphohumanreversed.fasta]
  • Tax_Id=9606 Gene_Symbol=DAND5 dante precursor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • DAN domain family member 5 precursor [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Q8N907; RecName: Full=DAN domain family member 5; AltName: Full=Cerberus-like protein 2; AltName: Full=Gremlin-3; AltName: Full=Cysteine knot superfamily 1, BMP antagonist 3; Flags: Precursor; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • DAN domain family member 5 OS=Homo sapiens GN=DAND5 [011711_HMR.fasta]
  • GeneSymbol=DAND5 Synonyms=CER2|CERL2|CKTSF1B3|COCO|CRL2|DANTE|GREM3|MGC126849|SP1 DAN domain family member 5 precursor [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00167536.1|SWISS-PROT:Q8N907|ENSEMBL:ENSP00000323155|REFSEQ:NP_689867|H-INV:HIT000020781 Tax_Id=9606 Gene_Symbol=DAND5 DAN domain family member 5 [ipi.HUMAN.20110912.fasta]
  • DAN domain family member 5 GN=DAND5 [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 189 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLGQLSTLL CLLSGALPTG SGRPEPQSPR PQSWAAANQT WALGPGALPP LVPASALGSW  60
   61 KAFLGLQKAR QLGMGRLQRG QDEVAAVTLP LNPQEVIQGM CKAVPFVQVF SRPGCSAIRL 120
  121 RNHLCFGHCS SLYIPGSDPT PLVLCNSCMP ARKRWAPVVL WCLTGSSASR RRVKISTMLI 180
  181 EGCHCSPKA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..189] FFAS03 1.06 Noggin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • receptor serine/threonine kinase binding
    		•  2.61683486163082 bayes_pls_golite062009
  • receptor binding
    		•  2.47511349613439 bayes_pls_golite062009
  • transforming growth factor beta receptor binding
    		•  2.39976050758366 bayes_pls_golite062009
  • transmembrane receptor protein serine/threonine kinase binding
    		•  2.39976050758366 bayes_pls_golite062009
  • binding
    		•  2.25218361714745 bayes_pls_golite062009
  • protein binding
    		•  1.92369246162193 bayes_pls_golite062009
  • growth factor activity
    		•  1.4973683227451 bayes_pls_golite062009
  • protein dimerization activity
    		•  0.878571015119069 bayes_pls_golite062009
  • protein homodimerization activity
    		•  0.678907830578514 bayes_pls_golite062009
  • identical protein binding
    		•  0.534614201318531 bayes_pls_golite062009
  • growth factor binding
    		•  0.4409182799008 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle