YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: MAN1A2

General Information:
Name(s) found: MAN1A2 [HGNC (HUGO)]
Description(s) found:
Found 32 descriptions.
SHOW ALL
  • mannosidase, alpha, class 1A, member 2 [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 641 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTPALLPLS GRRIPPLNLG PPSFPHHRAT LRLSEKFILL LILSAFITLC FGAFFFLPDS  60
   61 SKHKRFDLGL EDVLIPHVDA GKGAKNPGVF LIHGPDEHRH REEEERLRNK IRADHEKALE 120
  121 EAKEKLRKSR EEIRAEIQTE KNKVVQEMKI KENKPLPPVP IPNLVGIRGG DPEDNDIREK 180
  181 REKIKEMMKH AWDNYRTYGW GHNELRPIAR KGHSPNIFGS SQMGATIVDA LDTLYIMGLH 240
  241 DEFLDGQRWI EDNLDFSVNS EVSVFEVNIR FIGGLLAAYY LSGEEIFKIK AVQLAEKLLP 300
  301 AFNTPTGIPW AMVNLKSGVG RNWGWASAGS SILAEFGTLH MEFIHLSYLT GDLTYYKKVM 360
  361 HIRKLLQKMD RPNGLYPNYL NPRTGRWGQY HTSVGGLGDS FYEYLLKAWL MSDKTDHEAR 420
  421 KMYDDAIEAI EKHLIKKSRG GLTFIGEWKN GHLEKKMGHL ACFAGGMFAL GADGSRADKA 480
  481 GHYLELGAEI ARTCHESYDR TALKLGPESF KFDGAVEAVA VRQAEKYYIL RPEVIETYWY 540
  541 LWRFTHDPRY RQWGWEAALA IEKYCRVNGG FSGVKDVYSS TPTHDDVQQS FFLAETLKYL 600
  601 YLLFSGDDLL PLDHWVFNTE AHPLPVLHLA NTTLSGNPAV R

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..126] MSA 2.066992 View MSA. No confident structure predictions are available.
    2 View Details [127..641] PSI-BLAST 1000.0 Structure of mouse Golgi alpha-1,2-mannosidase IA reveals the molecular basis for substrate specificity among Class I enzymes (family 47 glycosidases)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • mannosyl-oligosaccharide mannosidase activity
    		•  7.089685350864 bayes_pls_golite062009
  • mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
    		•  6.95179264736435 bayes_pls_golite062009
  • mannosidase activity
    		•  5.20286438265852 bayes_pls_golite062009
  • hydrolase activity, hydrolyzing O-glycosyl compounds
    		•  4.31319275372149 bayes_pls_golite062009
  • hydrolase activity, acting on glycosyl bonds
    		•  3.65589746311782 bayes_pls_golite062009
  • hydrolase activity
    		•  2.67964748309919 bayes_pls_golite062009
  • binding
    		•  1.49199031708525 bayes_pls_golite062009
  • catalytic activity
    		•  1.31873306707813 bayes_pls_golite062009
  • cation binding
    		•  0.362242764130218 bayes_pls_golite062009
  • metal ion binding
    		•  0.362242764130218 bayes_pls_golite062009
  • protein binding
    		•  0.36081692928767 bayes_pls_golite062009
  • ion binding
    		•  0.355220167272296 bayes_pls_golite062009
  • calcium ion binding
    		•  0.121126738064555 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle