| Protein: | MAN1A2 |
| Organism: | Homo sapiens |
| Length: | 641 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MAN1A2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..641] | [1..641] |
|
|
0.0 | [1..641] | [1..658] |
|
|
0.0 | [1..641] | [1..641] |
|
|
0.0 | [1..641] | [1..641] |
|
|
0.0 | [1..641] | [1..641] |
|
Region A: Residues: [1-126] |
1 11 21 31 41 51
| | | | | |
1 MTTPALLPLS GRRIPPLNLG PPSFPHHRAT LRLSEKFILL LILSAFITLC FGAFFFLPDS 60
61 SKHKRFDLGL EDVLIPHVDA GKGAKNPGVF LIHGPDEHRH REEEERLRNK IRADHEKALE 120
121 EAKEKL
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [127-641] |
1 11 21 31 41 51
| | | | | |
1 RKSREEIRAE IQTEKNKVVQ EMKIKENKPL PPVPIPNLVG IRGGDPEDND IREKREKIKE 60
61 MMKHAWDNYR TYGWGHNELR PIARKGHSPN IFGSSQMGAT IVDALDTLYI MGLHDEFLDG 120
121 QRWIEDNLDF SVNSEVSVFE VNIRFIGGLL AAYYLSGEEI FKIKAVQLAE KLLPAFNTPT 180
181 GIPWAMVNLK SGVGRNWGWA SAGSSILAEF GTLHMEFIHL SYLTGDLTYY KKVMHIRKLL 240
241 QKMDRPNGLY PNYLNPRTGR WGQYHTSVGG LGDSFYEYLL KAWLMSDKTD HEARKMYDDA 300
301 IEAIEKHLIK KSRGGLTFIG EWKNGHLEKK MGHLACFAGG MFALGADGSR ADKAGHYLEL 360
361 GAEIARTCHE SYDRTALKLG PESFKFDGAV EAVAVRQAEK YYILRPEVIE TYWYLWRFTH 420
421 DPRYRQWGWE AALAIEKYCR VNGGFSGVKD VYSSTPTHDD VQQSFFLAET LKYLYLLFSG 480
481 DDLLPLDHWV FNTEAHPLPV LHLANTTLSG NPAVR
|
| Detection Method: | |
| Confidence: | 1000.0 |
| Match: | 1nxcA |
| Description: | Structure of mouse Golgi alpha-1,2-mannosidase IA reveals the molecular basis for substrate specificity among Class I enzymes (family 47 glycosidases) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| mannosyl-oligosaccharide mannosidase activity | 7.089685350864 | bayes_pls_golite062009 |
| mannosyl-oligosaccharide 1,2-alpha-mannosidase activity | 6.95179264736435 | bayes_pls_golite062009 |
| mannosidase activity | 5.20286438265852 | bayes_pls_golite062009 |
| hydrolase activity, hydrolyzing O-glycosyl compounds | 4.31319275372149 | bayes_pls_golite062009 |
| hydrolase activity, acting on glycosyl bonds | 3.65589746311782 | bayes_pls_golite062009 |
| hydrolase activity | 2.67964748309919 | bayes_pls_golite062009 |
| binding | 1.49199031708525 | bayes_pls_golite062009 |
| catalytic activity | 1.31873306707813 | bayes_pls_golite062009 |
| cation binding | 0.362242764130218 | bayes_pls_golite062009 |
| metal ion binding | 0.362242764130218 | bayes_pls_golite062009 |
| protein binding | 0.36081692928767 | bayes_pls_golite062009 |
| ion binding | 0.355220167272296 | bayes_pls_golite062009 |
| calcium ion binding | 0.121126738064555 | bayes_pls_golite062009 |
