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Protein Overview: CCS

General Information:
Name(s) found: CCS [HGNC (HUGO)]
Description(s) found:
Found 26 descriptions.
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  • copper chaperone for superoxide dismutase [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 274 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASDSGNQGT LCTLEFAVQM TCQSCVDAVR KSLQGVAGVQ DVEVHLEDQM VLVHTTLPSQ  60
   61 EVQALLEGTG RQAVLKGMGS GQLQNLGAAV AILGGPGTVQ GVVRFLQLTP ERCLIEGTID 120
  121 GLEPGLHGLH VHQYGDLTNN CNSCGNHFNP DGASHGGPQD SDRHRGDLGN VRADADGRAI 180
  181 FRMEDEQLKV WDVIGRSLII DEGEDDLGRG GHPLSKITGN SGERLACGII ARSAGLFQNP 240
  241 KQICSCDGLT IWEERGRPIA GKGRKESAQP PAHL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..85] PSI-BLAST 10.39794 The apo form of HMA domain of copper chaperone for superoxide dismutase
    2 View Details [86..274] PSI-BLAST 40.09691 Copper chaperone for superoxide dismutase, C-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • protein phosphatase 2B binding
    		•  13.5719110466797 bayes_pls_golite062009
  • superoxide dismutase activity
    		•  12.1093323949609 bayes_pls_golite062009
  • oxidoreductase activity, acting on superoxide radicals as acceptor
    		•  12.1093323949609 bayes_pls_golite062009
  • superoxide dismutase copper chaperone activity
    		•  5.30724557593005 bayes_pls_golite062009
  • chaperone binding
    		•  5.11696266714142 bayes_pls_golite062009
  • copper ion binding
    		•  4.51765925795625 bayes_pls_golite062009
  • copper chaperone activity
    		•  3.53752588768671 bayes_pls_golite062009
  • protein phosphatase binding
    		•  3.26481550276071 bayes_pls_golite062009
  • phosphatase binding
    		•  3.1414149853516 bayes_pls_golite062009
  • metallochaperone activity
    		•  2.82622922333955 bayes_pls_golite062009
  • copper ion transmembrane transporter activity
    		•  2.53311528765098 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.46331862428318 bayes_pls_golite062009
  • transition metal ion binding
    		•  2.451533032488 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  2.41954384727602 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.30916666149383 bayes_pls_golite062009
  • binding
    		•  2.28211284921339 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  2.0278666635337 bayes_pls_golite062009
  • protein binding
    		•  1.96660745768497 bayes_pls_golite062009
  • enzyme binding
    		•  1.82618630359051 bayes_pls_golite062009
  • metal ion binding
    		•  1.79413011653575 bayes_pls_golite062009
  • cation binding
    		•  1.79413011653575 bayes_pls_golite062009
  • ion binding
    		•  1.78699219376941 bayes_pls_golite062009
  • transition metal ion transmembrane transporter activity
    		•  1.64083855886256 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  1.63756992236587 bayes_pls_golite062009
  • transporter activity
    		•  1.33910763967058 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.12504351752996 bayes_pls_golite062009
  • catalytic activity
    		•  1.09233965765942 bayes_pls_golite062009
  • di-, tri-valent inorganic cation transmembrane transporter activity
    		•  0.704985452118462 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.618042428454534 bayes_pls_golite062009
  • zinc ion binding
    		•  0.25600715352161 bayes_pls_golite062009
  • antioxidant activity
    		•  0.240491838042064 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.80

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle