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Protein Overview: PPAP2B

General Information:
Name(s) found: PPAP2B [HGNC (HUGO)]
Description(s) found:
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  • gi|45504417|sp|O14495.1|LPP3_HUMAN RecName: Full=Lipid phosphate phosphohydrolase 3; AltName: Full=Phosphatidic acid phosphatase 2b; AltName: Full=PAP2-beta; Short=PAP-2b; Short=PAP2b; AltName: Full=Phosphatidate phosphohydrolase type 2b; AltName: Full=Va [NCBI NR]
  • gi|4105139|gb|AAD02271.1| type-2 phosphatidic acid phosphatase-beta; phosphatidate phosphohydrolase; phospholipid phosphatase [Homo sapiens] [NCBI NR]
  • gi|3047173|gb|AAC63433.1| phosphatidic acid phosphohydrolase homolog [Homo sapiens] [NCBI NR]
  • gi|29422123|gb|AAO84481.1|AF480883_1 vascular endothelial growth factor and type I collagen inducible protein [Homo sapiens] [NCBI NR]
  • gi|29171742|ref|NP_803133.1| phosphatidic acid phosphatase type 2B [Homo sapiens] [NCBI NR]
  • gi|29171740|ref|NP_003704.3| phosphatidic acid phosphatase type 2B [Homo sapiens] [NCBI NR]
  • gi|2467300|dbj|BAA22594.1| phosphatidic acid phosphatase 2b [Homo sapiens] [NCBI NR]
  • gi|189065509|dbj|BAG35348.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|119627058|gb|EAX06653.1| phosphatidic acid phosphatase type 2B, isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119627057|gb|EAX06652.1| phosphatidic acid phosphatase type 2B, isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119627056|gb|EAX06651.1| phosphatidic acid phosphatase type 2B, isoform CRA_a [Homo sapiens] [NCBI NR]
  • phosphatidic acid phosphatase type 2B [HGNC (HUGO)]
  • Phospholipid phosphatase 3 OS=Homo sapiens GN=PLPP3 PE=1 SV=1 [Swiss-Prot]
  • Lipid phosphate phosphohydrolase 3 OS=Homo sapiens GN=PPAP2B PE=1 SV=1 [Swiss-Prot]
  • PHOSPHATIDIC acid phosphatase 2B [hmr_yeast5_DM3-1_pombe.fasta]
  • phosphatidic acid phosphatase type 2B; phosphatidic acid phosphohydrolase; vascular endothelial growth factor and type I collagen inducible; type-2 phosphatidic acid phosphatase-beta [HMR_022704.fasta]
  • phosphatidic acid phosphatase type 2B [Homo sapiens]gi|29171740|ref|NP_003704.3| phosphatidic acid phosphatase type 2B [Homo sapiens]gi|29422123|gb|AAO84481.1| vascular endothelial growth factor and type I collagen inducible protein [Homo sapiens]gi|45 [nrdb_11152004_Chlamydomonas]
  • phosphatidic acid phosphatase type 2B; phosphatidic acid phosphohydrolase; type-2 phosphatidic acid phosphatase-beta; vascular endothelial growth factor and type I collagen inducible [Human2242005.fasta]
  • Lipid phosphate phosphohydrolase 3 (Phosphatidic acid phosphatase 2b) (Phosphatidate phosphohydrolase type 2b) (PAP2b) (PAP-2b) (PAP2-beta) (Vascular endothelial growth factor and type I collagen inducible protein) (VCIP) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Lipid phosphate phosphohydrolase 3 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • phosphatidic acid phosphatase type 2B [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • phosphatidic acid phosphatase type 2B; phosphatidic acid phosphohydrolase; type-2 phosphatidic acid phosphatase-beta; vascular endothelial growth factor and type I collagen inducible [Homo sapiens] [HumanGallus06162005.fasta]
  • phosphatidic acid phosphatase type 2B; phosphatidic acid phosphohydrolase; vascular endothelial growth factor and type I collagen inducible; type-2 phosphatidic acid phosphatase-beta [Homo sapiens] [human-NCBI-042104-rand.fasta]
  • Lipid phosphate phosphohydrolase 3 (Phosphatidic acid phosphatase 2b) (PAP2-beta) (PAP-2b) (PAP2b) (Phosphatidate phosphohydrolase type 2b) (Vascular endothelial growth factor and type I collagen-inducible protein) (VCIP) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • phosphatidic acid phosphatase type 2B, isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • vascular endothelial growth factor and type I collagen inducible protein [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • type-2 phosphatidic acid phosphatase-beta; phosphatidate phosphohydrolase; phospholipid phosphatase [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • phosphatidic acid phosphohydrolase homolog [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • phosphatidic acid phosphatase 2b [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 LIPID PHOSPHATE PHOSPHOHYDROLASE 3 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=PPAP2B Lipid phosphate phosphohydrolase 3 [human-ipi-250309-contam.fasta]
  • Lipid phosphate phosphohydrolase 3 (Phosphatidic acid phosphatase 2b) (Phosphatidate phosphohydrolase type 2b) (PAP2b) (PAP-2b) (PAP2-beta) (Vascular endothelial growth factor and type I collagen-inducible protein) (VCIP) [nr-271106-contam.fasta]
  • IPI:IPI00021453.1|SWISS-PROT:O14495|TREMBL:B2R651;Q5U0F7|ENSEMBL:ENSP00000294390;ENSP00000360296;ENSP00000409503|REFSEQ:NP_003704;NP_803133|H-INV:HIT000062443|VEGA:OTTHUMP00000009855 Tax_Id=9606 Gene_Symbol=PPAP2B Lipid phosphate phosphohydrolase 3 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=PPAP2B Lipid phosphate phosphohydrolase 3 ENSG00000162407 IPI00021453 [drosphohumanreversed.fasta]
  • lipid phosphate phosphohydrolase 3 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • O14495;B2R651;Q96GW0;Q99782; RecName: Full=Lipid phosphate phosphohydrolase 3; AltName: Full=Phosphatidic acid phosphatase 2b; AltName: Full=PAP2-beta; AltName: Full=Phosphatidate phosphohydrolase type 2b; AltName: Full=Vascular endothelial growth factor and type I collagen-inducible protein; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Lipid phosphate phosphohydrolase 3 OS=Homo sapiens GN=PPAP2B [011711_HMR.fasta]
  • IPI:IPI00021453.1|SWISS-PROT:O14495|TREMBL:D3DQ52;Q5U0F7|ENSEMBL:ENSP00000294390;ENSP00000360296;ENSP00000409503|REFSEQ:NP_003704;NP_803133|H-INV:HIT000062443|VEGA:OTTHUMP00000009855 Tax_Id=9606 Gene_Symbol=PPAP2B Lipid phosphate phosphohydrolase 3 [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=PPAP2B Synonyms=Dri42|LPP3|MGC15306|PAP2B|VCIP lipid phosphate phosphohydrolase 3 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00021453.1|SWISS-PROT:O14495|TREMBL:Q5U0F7|ENSEMBL:ENSP00000360296|REFSEQ:NP_003704|H-INV:HIT000062443|VEGA:OTTHUMP00000009855 Tax_Id=9606 Gene_Symbol=PPAP2B Lipid phosphate phosphohydrolase 3 [ipi.HUMAN.20110912.fasta]
  • Lipid phosphate phosphohydrolase 3 GN=PPAP2B [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 311 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQNYKYDKAI VPESKNGGSP ALNNNPRRSG SKRVLLICLD LFCLFMAGLP FLIIETSTIK  60
   61 PYHRGFYCND ESIKYPLKTG ETINDAVLCA VGIVIAILAI ITGEFYRIYY LKKSRSTIQN 120
  121 PYVAALYKQV GCFLFGCAIS QSFTDIAKVS IGRLRPHFLS VCNPDFSQIN CSEGYIQNYR 180
  181 CRGDDSKVQE ARKSFFSGHA SFSMYTMLYL VLYLQARFTW RGARLLRPLL QFTLIMMAFY 240
  241 TGLSRVSDHK HHPSDVLAGF AQGALVACCI VFFVSDLFKT KTTLSLPAPA IRKEILSPVD 300
  301 IIDRNNHHNM M

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..102] MSA 2.695996 View MSA. No confident structure predictions are available.
    2 View Details [103..311] PSI-BLAST 10.0 Bacterial acid phosphatase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • phosphatase activity
    		•  5.12905336348033 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  4.9347909214714 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  4.04405253821642 bayes_pls_golite062009
  • hydrolase activity
    		•  3.00055386714268 bayes_pls_golite062009
  • catalytic activity
    		•  0.767627914425245 bayes_pls_golite062009
  • acid phosphatase activity
    		•  0.477884904859676 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle