Protein Overview: TRMT6

General Information:
Name(s) found:	TRMT6 [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|74753354\|sp\|Q9UJA5.1\|TRM6_HUMAN RecName: Full=tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6; AltName: Full=tRNA(m1A58)-methyltransferase subunit TRM6; Short=tRNA(m1A58)MTase subunit TRM6 [NCBI NR] gi\|5834567\|emb\|CAB55274.1\| CGI-09 protein [Homo sapiens] [NCBI NR] gi\|19923475\|ref\|NP_057023.2\| tRNA methyltransferase 6 [Homo sapiens] [NCBI NR] gi\|12654837\|gb\|AAH01262.1\| TRNA methyltransferase 6 homolog (S. cerevisiae) [Homo sapiens] [NCBI NR] gi\|119630811\|gb\|EAX10406.1\| CGI-09 protein, isoform CRA_a [Homo sapiens] [NCBI NR] tRNA methyltransferase 6 homolog (S. cerevisiae) [HGNC (HUGO)] tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 OS=Homo sapiens GN=TRMT6 PE=1 SV=1 [Swiss-Prot] DJ967N21.3 [hmr_yeast5_DM3-1_pombe.fasta] CGI-09 protein [HMR_022704.fasta] CGI-09 protein [Homo sapiens]gi\|12654837\|gb\|AAH01262.1\| CGI-09 protein [Homo sapiens]gi\|5834567\|emb\|CAB55274.1\| dJ967N21.3.1 (novel protein (isoform 1)) [Homo sapiens] [nrdb_11152004_Chlamydomonas] Tax_Id=9606 Splice Isoform 1 of tRNA [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta] (NM_015939) CGI-09 protein [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] CGI-09 protein [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta] Tax_Id=9606 OTTHUMP00000030210 [EBI-IPI_human_3.12_11-03-2005_con_reversed.fasta] tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6 (tRNA(m1A58)-methyltransferase subunit TRM6) (tRNA(m1A58)MTase subunit TRM6) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] tRNA methyltransferase 6 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] TRNA methyltransferase 6 homolog (S. cerevisiae) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] CGI-09 protein, isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tax_Id=9606 Isoform 1 of tRNA [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta] Tax_Id=9606 DJ967N21.3.1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=9606 Gene_Symbol=TRMT6 Isoform 1 of tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6 [human-ipi-250309-contam.fasta] OTTHUMP00000030210 [Homo sapiens] [nr-271106-contam.fasta] IPI:IPI00099311.3\|SWISS-PROT:Q9UJA5-1\|TREMBL:B4DUV6\|ENSEMBL:ENSP00000203001\|REFSEQ:NP_057023\|H-INV:HIT000286822\|VEGA:OTTHUMP00000030210 Tax_Id=9606 Gene_Symbol=TRMT6 Isoform 1 of tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6 [ipi.HUMAN.fasta.20090807] [human_BMb_040710_contam.fasta] Tax_Id=9606 Gene_Symbol=TRMT6 Isoform 1 of tRNA ENSG00000089195 IPI00099311 IPI00155747 [drosphohumanreversed.fasta] Tax_Id=9606 Gene_Symbol=CGI-09 Isoform 1 of tRNA [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta] tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6 OS=Homo sapiens GN=TRMT6 PE=1 SV=1 [UniProtHuman070710.fasta] Q9UJA5;Q76P92;Q9BQV5;Q9ULR7;Q9Y2Z8; RecName: Full=tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6; AltName: Full=tRNA(m1A58)-methyltransferase subunit TRM6; [UniProt_Human_2010_06_06-01-2010_reversed.fasta] Isoform 1 of tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6 OS=Homo sapiens GN=TRMT6 [011711_HMR.fasta] GeneSymbol=TRMT6 Synonyms=GCD10\|Gcd10p\|MGC5029 tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] IPI:IPI00099311.3\|SWISS-PROT:Q9UJA5-1\|ENSEMBL:ENSP00000203001\|REFSEQ:NP_057023\|H-INV:HIT000286822\|VEGA:OTTHUMP00000030210 Tax_Id=9606 Gene_Symbol=TRMT6 Isoform 1 of tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6 [ipi.HUMAN.20110912.fasta] tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 GN=TRMT6 [Doctor+uniprot-HUMAN-120911.fasta]
Organism:	Homo sapiens
Length:	497 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEGSGEQPGP QPQHPGDHRI RDGDFVVLKR EDVFKAVQVQ RRKKVTFEKQ WFYLDNVIGH  60
   61 SYGTAFEVTS GGSLQPKKKR EEPTAETKEA GTDNRNIVDD GKSQKLTQDD IKALKDKGIK 120
  121 GEEIVQQLIE NSTTFRDKTE FAQDKYIKKK KKKYEAIITV VKPSTRILSI MYYAREPGKI 180
  181 NHMRYDTLAQ MLTLGNIRAG NKMIVMETCA GLVLGAMMER MGGFGSIIQL YPGGGPVRAA 240
  241 TACFGFPKSF LSGLYEFPLN KVDSLLHGTF SAKMLSSEPK DSALVEESNG TLEEKQASEQ 300
  301 ENEDSMAEAP ESNHPEDQET METISQDPEH KGPKERGSKK DYIQEKQRRQ EEQRKRHLEA 360
  361 AALLSERNAD GLIVASRFHP TPLLLSLLDF VAPSRPFVVY CQYKEPLLEC YTKLRERGGV 420
  421 INLRLSETWL RNYQVLPDRS HPKLLMSGGG GYLLSGFTVA MDNLKADTSL KSNASTLESH 480
  481 ETEEPAAKKR KCPESDS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MIS12	No Comments	Cheeseman, I.M., et al. (2004)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..497]	FFAS03	2.32	Probable methyltransferase Rv2118c

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.87

Protein Overview: TRMT6

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: