Protein Overview: CDKN1B

General Information:
Name(s) found:	CDKN1B [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|516559\|gb\|AAA20240.1\| p27kip1 [NCBI NR] gi\|48146915\|emb\|CAG33680.1\| CDKN1B [Homo sapiens] [NCBI NR] gi\|4757962\|ref\|NP_004055.1\| cyclin-dependent kinase inhibitor 1B [Homo sapiens] [NCBI NR] gi\|197692547\|dbj\|BAG70237.1\| cyclin-dependent kinase inhibitor 1B [Homo sapiens] [NCBI NR] gi\|197692283\|dbj\|BAG70105.1\| cyclin-dependent kinase inhibitor 1B [Homo sapiens] [NCBI NR] gi\|189065529\|dbj\|BAG35368.1\| unnamed protein product [Homo sapiens] [NCBI NR] gi\|18656929\|gb\|AAL78041.1\|AF480891_1 cyclin-dependent kinase inhibitor 1B (p27, Kip1) [Homo sapiens] [NCBI NR] gi\|119616681\|gb\|EAW96275.1\| cyclin-dependent kinase inhibitor 1B (p27, Kip1), isoform CRA_a [Homo sapiens] [NCBI NR] gi\|1168871\|sp\|P46527.1\|CDN1B_HUMAN RecName: Full=Cyclin-dependent kinase inhibitor 1B; AltName: Full=Cyclin-dependent kinase inhibitor p27; AltName: Full=p27Kip1 [NCBI NR] cyclin-dependent kinase inhibitor 1B (p27, Kip1) [HGNC (HUGO)] (P46527) Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1) [Swiss-Prot] Cyclin-dependent kinase inhibitor 1B OS=Homo sapiens GN=CDKN1B PE=1 SV=1 [Swiss-Prot] Cyclin-dependent kinase inhibitor 1B [hmr_yeast5_DM3-1_pombe.fasta] cyclin-dependent kinase inhibitor 1B [HMR_022704.fasta] cyclin-dependent kinase inhibitor 1B [Homo sapiens]gi\|18656929\|gb\|AAL78041.1\| cyclin-dependent kinase inhibitor 1B (p27, Kip1) [Homo sapiens]gi\|48146915\|emb\|CAG33680.1\| CDKN1B [Homo sapiens]gi\|1168871\|sp\|P46527\|CDNB_HUMAN Cyclin-dependent kinase inhibi [nrdb_11152004_Chlamydomonas] Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1) [Yateslab_human_na_07-28-2006_reversed.fasta] Tax_Id=9606 Cyclin-dependent kinase inhibitor 1B [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta] (NM_004064) cyclin-dependent kinase inhibitor 1B [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] cyclin-dependent kinase inhibitor 1B [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta] unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] cyclin-dependent kinase inhibitor 1B (p27, Kip1), isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] CDKN1B [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] cyclin-dependent kinase inhibitor 1B (p27, Kip1) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] p27kip1 [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tax_Id=9606 CYCLIN-DEPENDENT KINASE INHIBITOR 1B [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] RecName: Full=Cyclin-dependent kinase inhibitor 1B; AltName: Full=Cyclin-dependent kinase inhibitor p27; AltName: Full=p27Kip1 [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta] Tax_Id=9606 Gene_Symbol=CDKN1B Cyclin-dependent kinase inhibitor 1B [human-ipi-250309-contam.fasta] IPI:IPI00006991.1\|SWISS-PROT:P46527\|TREMBL:B4DPH2;O43806;Q6I9V6;Q708J1;Q96TE0;Q9NYG6;Q9UH60\|ENSEMBL:ENSP00000228872\|REFSEQ:NP_004055\|H-INV:HIT000218019\|VEGA:OTTHUMP00000195098 Tax_Id=9606 Gene_Symbol=CDKN1B Cyclin-dependent kinase inhibitor 1B [ipi.HUMAN.fasta.20090807] [human_BMb_040710_contam.fasta] P46527;Q16307;Q5U0H2;Q9BUS6; RecName: Full=Cyclin-dependent kinase inhibitor 1B; AltName: Full=Cyclin-dependent kinase inhibitor p27; AltName: Full=p27Kip1; [UniProt_Human_2010_06_06-01-2010_reversed.fasta] Cyclin-dependent kinase inhibitor 1B OS=Homo sapiens GN=CDKN1B [011711_HMR.fasta] GeneSymbol=CDKN1B Synonyms=CDKN4\|KIP1\|MEN1B\|MEN4\|P27KIP1 cyclin-dependent kinase inhibitor 1B [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] IPI:IPI00006991.1\|SWISS-PROT:P46527\|TREMBL:O43806;Q6I9V6;Q96TE0;Q9NYG6\|ENSEMBL:ENSP00000228872\|REFSEQ:NP_004055\|H-INV:HIT000218019\|VEGA:OTTHUMP00000195098 Tax_Id=9606 Gene_Symbol=CDKN1B Cyclin-dependent kinase inhibitor 1B [ipi.HUMAN.20110912.fasta] Cyclin-dependent kinase inhibitor 1B GN=CDKN1B [Doctor+uniprot-HUMAN-120911.fasta] CDKN1B protein OS=Homo sapiens GN=CDKN1B PE=2 SV=1 [uniprot-human-031015-contam.fasta]
Organism:	Homo sapiens
Length:	198 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNVRVSNGS PSLERMDARQ AEHPKPSACR NLFGPVDHEE LTRDLEKHCR DMEEASQRKW  60
   61 NFDFQNHKPL EGKYEWQEVE KGSLPEFYYR PPRPPKGACK VPAQESQDVS GSRPAAPLIG 120
  121 APANSEDTHL VDPKTDPSDS QTGLAEQCAG IRKRPATDDS STQNKRANRT EENVSDGSPN 180
  181 AGSVEQTPKK PGLRRRQT

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..106]	PSI-BLAST	37.0	P27(KIP1) fragment 22-106
2	View Details	[107..198]	MSA	2.026995	View MSA. No confident structure predictions are available.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: CDKN1B

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: