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View Structure Prediction Details

Protein: CDKN1B
Organism: Homo sapiens
Length: 198 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CDKN1B.

Description E-value Query
Range
Subject
Range
gi|76616328 - gi|76616328|ref|XP_590159.2| PREDICTED: similar to Cyclin-dependent kinase inhibitor 1B (Cyclin-depe...
1.0E-82 [1..198] [301..498]
CDN1B_FELCA - Cyclin-dependent kinase inhibitor 1B OS=Felis catus GN=CDKN1B PE=2 SV=1
6.0E-79 [1..198] [1..198]
gi|54695974, gi|... - gi|61368072|gb|AAX43097.1| cyclin-dependent kinase inhibitor 1B [synthetic construct], gi|61368067|g...
3.0E-78 [1..198] [1..198]
gi|7769665 - gi|7769665|gb|AAF69497.1| cyclin-dependent kinase inhibitor p27kip1 [Homo sapiens]
3.0E-78 [1..198] [1..198]
gi|47523690, gi|... - gi|57157157|dbj|BAD83613.1| p27Kip1 [Sus scrofa], gi|47523690|ref|NP_999481.1| cyclin-dependent kina...
2.0E-77 [1..198] [1..198]

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Predicted Domain #1
Region A:
Residues: [1-106]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNVRVSNGS PSLERMDARQ AEHPKPSACR NLFGPVDHEE LTRDLEKHCR DMEEASQRKW  60
   61 NFDFQNHKPL EGKYEWQEVE KGSLPEFYYR PPRPPKGACK VPAQES

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.0
Match: 1jsuC
Description: P27(KIP1) fragment 22-106
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [107-198]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QDVSGSRPAA PLIGAPANSE DTHLVDPKTD PSDSQTGLAE QCAGIRKRPA TDDSSTQNKR  60
   61 ANRTEENVSD GSPNAGSVEQ TPKKPGLRRR QT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle