YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: CDKN1B
Organism: Homo sapiens
Length: 198 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CDKN1B.

Description E-value Query
Range
Subject
Range
gi|76616328 - gi|76616328|ref|XP_590159.2| PREDICTED: similar to Cyclin-dependent kinase inhibitor 1B (Cyclin-depe...
1.0E-82 [1..198] [301..498]
CDN1B_FELCA - Cyclin-dependent kinase inhibitor 1B OS=Felis catus GN=CDKN1B PE=2 SV=1
6.0E-79 [1..198] [1..198]
gi|54695974, gi|... - gi|61368072|gb|AAX43097.1| cyclin-dependent kinase inhibitor 1B [synthetic construct], gi|61368067|g...
3.0E-78 [1..198] [1..198]
gi|7769665 - gi|7769665|gb|AAF69497.1| cyclin-dependent kinase inhibitor p27kip1 [Homo sapiens]
3.0E-78 [1..198] [1..198]
gi|47523690, gi|... - gi|57157157|dbj|BAD83613.1| p27Kip1 [Sus scrofa], gi|47523690|ref|NP_999481.1| cyclin-dependent kina...
2.0E-77 [1..198] [1..198]

Back

Predicted Domain #1
Region A:
Residues: [1-106]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNVRVSNGS PSLERMDARQ AEHPKPSACR NLFGPVDHEE LTRDLEKHCR DMEEASQRKW  60
   61 NFDFQNHKPL EGKYEWQEVE KGSLPEFYYR PPRPPKGACK VPAQES

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.0
Match: 1jsuC
Description: P27(KIP1) fragment 22-106
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [107-198]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QDVSGSRPAA PLIGAPANSE DTHLVDPKTD PSDSQTGLAE QCAGIRKRPA TDDSSTQNKR  60
   61 ANRTEENVSD GSPNAGSVEQ TPKKPGLRRR QT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.219 0.175 cytosol a.1.1 Globin-like
View Download 0.292 0.171 cyclin-dependent protein kinase inhibitor activity c.3.1 FAD/NAD(P)-binding domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle