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Protein Overview: TNFSF4

General Information:
Name(s) found: TNFSF4 [HGNC (HUGO)]
Description(s) found:
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  • gi|56202617|emb|CAI20416.1| tumor necrosis factor (ligand) superfamily, member 4 [Homo sapiens] [NCBI NR]
  • gi|510294|emb|CAA56284.1| OX 40 ligand/ gp 34 [Homo sapiens] [NCBI NR]
  • gi|4507603|ref|NP_003317.1| tumor necrosis factor (ligand) superfamily, member 4 [Homo sapiens] [NCBI NR]
  • emb|CAA18438.1| dJ395P12.2 (tax-transcriptionally activated glycoprotein 1 (34kD) (OX40 ligand, OX40L)) [Homo sapiens] [NCBI NR]
  • gi|219666|dbj|BAA14259.1| glycoprotein 34 [Homo sapiens] [NCBI NR]
  • gi|121540|sp|P23510.1|TNFL4_HUMAN RecName: Full=Tumor necrosis factor ligand superfamily member 4; AltName: Full=OX40 ligand; Short=OX40L; AltName: Full=Glycoprotein Gp34; AltName: Full=TAX transcriptionally-activated glycoprotein 1; AltName: CD_antigen=C [NCBI NR]
  • gi|119611346|gb|EAW90940.1| tumor necrosis factor (ligand) superfamily, member 4 (tax-transcriptionally activated glycoprotein 1, 34kDa), isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119611344|gb|EAW90938.1| tumor necrosis factor (ligand) superfamily, member 4 (tax-transcriptionally activated glycoprotein 1, 34kDa), isoform CRA_a [Homo sapiens] [NCBI NR]
  • pir||A39680 34K glycoprotein, HTLV-1-induced - human [NCBI NR]
  • tumor necrosis factor (ligand) superfamily, member 4 [HGNC (HUGO)]
  • Tumor necrosis factor ligand superfamily member 4 OS=Homo sapiens GN=TNFSF4 PE=1 SV=1 [Swiss-Prot]
  • (P23510) Tumor necrosis factor ligand superfamily member 4 (OX40 ligand) (OX40L) (Glycoprotein GP34) (TAX-transcriptionally activated glycoprotein 1) [Swiss-Prot]
  • Tumor necrosis factor ligand superfamily member 4 [hmr_yeast5_DM3-1_pombe.fasta]
  • tumor necrosis factor (ligand) superfamily, member 4; tax-transcriptionally activated glycoprotein 1 (34kD); glycoprotein 34 kd; OX40 ligand; OX40 antigen ligand; CD134 ligand [HMR_022704.fasta]
  • tumor necrosis factor (ligand) superfamily, member 4; tax-transcriptionally activated glycoprotein 1 (34kD); glycoprotein 34 kd; OX40 ligand; OX40 antigen ligand; CD134 ligand; tumor necrosis factor (ligand) superfamily, member 4 (tax-transcriptionally ac [071204_hmrz_cont.fasta]
  • tumor necrosis factor (ligand) superfamily, member 4 [Homo sapiens]gi|219666|dbj|BAA14259.1| glycoprotein 34 [Homo sapiens]gi|3738129|emb|CAA18438.1| dJ395P12.2 (tax-transcriptionally activated glycoprotein 1 (34kD) (OX40 ligand, OX40L)) [Homo sapiens] [nrdb_11152004_Chlamydomonas]
  • Tumor necrosis factor ligand superfamily member 4 (OX40 ligand) (OX40L) (Glycoprotein GP34) (TAX-transcriptionally activated glycoprotein 1) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Tumor necrosis factor ligand superfamily member 4 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_003326) tumor necrosis factor (ligand) superfamily, member 4 (tax-transcriptionally activated glycoprotein 1, 34kD); tax-transcriptionally activated glycoprotein 1 (34kD) [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • tumor necrosis factor (ligand) superfamily, member 4 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • tumor necrosis factor (ligand) superfamily, member 4; tax-transcriptionally activated glycoprotein 1 (34kD); glycoprotein 34 kd; OX40 ligand; OX40 antigen ligand; CD134 ligand [Homo sapiens] [human-NCBI-042104-rand.fasta]
  • Tumor necrosis factor ligand superfamily member 4 (OX40 ligand) (OX40L) (Glycoprotein Gp34) (TAX transcriptionally-activated glycoprotein 1) (CD252 antigen) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • tumor necrosis factor (ligand) superfamily, member 4 (tax-transcriptionally activated glycoprotein 1, 34kDa) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • glycoprotein 34 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • tumor necrosis factor (ligand) superfamily, member 4 (tax-transcriptionally activated glycoprotein 1, 34kDa), isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • OX 40 ligand/ gp 34 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 4 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=TNFSF4 Tumor necrosis factor ligand superfamily member 4 [human-ipi-250309-contam.fasta]
  • IPI:IPI00011974.1|SWISS-PROT:P23510|TREMBL:Q5JZA5;Q6FGS4|ENSEMBL:ENSP00000281834|REFSEQ:NP_003317|H-INV:HIT000102071|VEGA:OTTHUMP00000032704 Tax_Id=9606 Gene_Symbol=TNFSF4 Tumor necrosis factor ligand superfamily member 4 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=TNFSF4 Tumor necrosis factor ligand superfamily member 4 ENSG00000117586 IPI00011974 IPI00647536 [drosphohumanreversed.fasta]
  • tumor necrosis factor ligand superfamily member 4 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • P23510;Q5JZA5;Q9HCN9; RecName: Full=Tumor necrosis factor ligand superfamily member 4; AltName: Full=OX40 ligand; AltName: Full=Glycoprotein Gp34; AltName: Full=TAX transcriptionally-activated glycoprotein 1; AltName: CD_antigen=CD252; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Tumor necrosis factor ligand superfamily member 4 OS=Homo sapiens GN=TNFSF4 [011711_HMR.fasta]
  • IPI:IPI00011974.1|SWISS-PROT:P23510|TREMBL:Q6FGS4|ENSEMBL:ENSP00000281834|REFSEQ:NP_003317|H-INV:HIT000102071|VEGA:OTTHUMP00000032704 Tax_Id=9606 Gene_Symbol=TNFSF4 Tumor necrosis factor ligand superfamily member 4 [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=TNFSF4 Synonyms=CD134L|CD252|GP34|OX-40L|OX4OL|TXGP1 tumor necrosis factor ligand superfamily member 4 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • Tumor necrosis factor ligand superfamily member 4 GN=TNFSF4 [Doctor+uniprot-HUMAN-120911.fasta]
  • Tumor necrosis factor (Ligand) superfamily, member 4 (Tax-transcriptionally activated glycoprotein 1, 34kDa), isoform CRA_a OS=Homo sapiens GN=TNFSF4 PE=4 SV=1 [uniprot-human-031015-contam.fasta]
    • Organism: Homo sapiens
    Length: 183 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERVQPLEEN VGNAARPRFE RNKLLLVASV IQGLGLLLCF TYICLHFSAL QVSHRYPRIQ  60
   61 SIKVQFTEYK KEKGFILTSQ KEDEIMKVQN NSVIINCDGF YLISLKGYFS QEVNISLHYQ 120
  121 KDEEPLFQLK KVRSVNSLMV ASLTYKDKVY LNVTTDNTSL DDFHVNGGEL ILIHQNPGEF 180
  181 CVL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..183] PSI-BLAST 61.39794 No description for 2hevF was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • tumor necrosis factor receptor binding
    		•  4.97032095500332 bayes_pls_golite062009
  • tumor necrosis factor receptor superfamily binding
    		•  2.83043724362524 bayes_pls_golite062009
  • receptor binding
    		•  2.30826967264465 bayes_pls_golite062009
  • protein binding
    		•  2.25413201891408 bayes_pls_golite062009
  • CD40 receptor binding
    		•  1.92939268560534 bayes_pls_golite062009
  • binding
    		•  1.55055236820725 bayes_pls_golite062009
  • cell surface binding
    		•  1.54737106887049 bayes_pls_golite062009
  • eukaryotic cell surface binding
    		•  1.02834426035531 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle