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Protein Overview: FTSJ1

General Information:
Name(s) found: FTSJ1 [HGNC (HUGO)]
Description(s) found:
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  • gi|7110661|ref|NP_036412.1| FtsJ homolog 1 isoform a [Homo sapiens] [NCBI NR]
  • gi|3334739|emb|CAA06749.1| JM23 [Homo sapiens] [NCBI NR]
  • gi|23270836|gb|AAH23584.1| FtsJ homolog 1 (E. coli) [Homo sapiens] [NCBI NR]
  • gi|189054765|dbj|BAG37587.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|12643879|sp|Q9UET6.2|RRMJ1_HUMAN RecName: Full=Putative ribosomal RNA methyltransferase 1; AltName: Full=rRNA (uridine-2'-O-)-methyltransferase [NCBI NR]
  • gi|119571168|gb|EAW50783.1| FtsJ homolog 1 (E. coli), isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119571167|gb|EAW50782.1| FtsJ homolog 1 (E. coli), isoform CRA_a [Homo sapiens] [NCBI NR]
  • FtsJ homolog 1 (E. coli) [HGNC (HUGO)]
  • Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase OS=Homo sapiens GN=FTSJ1 PE=1 SV=2 [Swiss-Prot]
  • Putative ribosomal RNA methyltransferase 1 OS=Homo sapiens GN=FTSJ1 PE=1 SV=2 [Swiss-Prot]
  • (Q9UET6) Putative ribosomal RNA methyltransferase 1 (EC 2.1.1.-) (rRNA (uridine-2'-O-)-methyltransferase) (JM23 protein) [Swiss-Prot]
  • Putative ribosomal RNA methyltransferase 1 [hmr_yeast5_DM3-1_pombe.fasta]
  • FtsJ homolog 1 isoform a; cell division protein; rRNA (uridine-2'-O-)-methyltransferase [HMR_022704.fasta]
  • FtsJ homolog 1 isoform a; rRNA (uridine-2'-O-)-methyltransferase; cell division protein [071204_hmrz_cont.fasta]
  • FtsJ homolog 1 isoform a [Homo sapiens]gi|23270836|gb|AAH23584.1| FtsJ homolog 1, isoform a [Homo sapiens]gi|3334739|emb|CAA06749.1| JM23 [Homo sapiens]gi|12643879|sp|Q9UET6|RRM1_HUMAN Putative ribosomal RNA methyltransferase 1 (rRNA (uridine-2'-O-)-me [nrdb_11152004_Chlamydomonas]
  • Putative ribosomal RNA methyltransferase 1 (rRNA (uridine-2'-O-)-methyltransferase) (JM23 protein) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Putative ribosomal RNA methyltransferase 1 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_012280) FTSJ1; homolog of yeast SPB1 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • FtsJ homolog 1 isoform a [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • FtsJ homolog 1 isoform a; rRNA (uridine-2'-O-)-methyltransferase; cell division protein [Homo sapiens] [HumanGallus06162005.fasta]
  • FtsJ homolog 1 isoform a; cell division protein; rRNA (uridine-2'-O-)-methyltransferase [Homo sapiens] [human-NCBI-042104-rand.fasta]
  • Putative ribosomal RNA methyltransferase 1 (rRNA (uridine-2'-O-)-methyltransferase) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • FtsJ homolog 1 (E. coli), isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • FtsJ homolog 1 (E. coli) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • JM23 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 PUTATIVE RIBOSOMAL RNA METHYLTRANSFERASE 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • RecName: Full=Putative ribosomal RNA methyltransferase 1; AltName: Full=rRNA (uridine-2'-O-)-methyltransferase [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=FTSJ1 Putative ribosomal RNA methyltransferase 1 [human-ipi-250309-contam.fasta]
  • IPI:IPI00004308.1|SWISS-PROT:Q9UET6|TREMBL:B2RCJ0;B7Z4K4|ENSEMBL:ENSP00000326948|REFSEQ:NP_036412|H-INV:HIT000274962|VEGA:OTTHUMP00000025795 Tax_Id=9606 Gene_Symbol=FTSJ1 Putative ribosomal RNA methyltransferase 1 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=FTSJ1 Putative ribosomal RNA methyltransferase 1 ENSG00000068438 IPI00219764 IPI00004308 [drosphohumanreversed.fasta]
  • putative ribosomal RNA methyltransferase 1 isoform a [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Q9UET6;B2RCJ0;O75670; RecName: Full=Putative ribosomal RNA methyltransferase 1; AltName: Full=rRNA (uridine-2'-O-)-methyltransferase; AltName: Full=Protein ftsJ homolog 1; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Putative ribosomal RNA methyltransferase 1 OS=Homo sapiens GN=FTSJ1 [011711_HMR.fasta]
  • IPI:IPI00004308.1|SWISS-PROT:Q9UET6|TREMBL:B7Z4K4|ENSEMBL:ENSP00000326948|REFSEQ:NP_036412|H-INV:HIT000274962|VEGA:OTTHUMP00000025795 Tax_Id=9606 Gene_Symbol=FTSJ1 Putative ribosomal RNA methyltransferase 1 [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=FTSJ1 Synonyms=CDLIV|MRX44|MRX9|SPB1|TRM7 putative ribosomal RNA methyltransferase 1 isoform a [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00004308.1|SWISS-PROT:Q9UET6-1|ENSEMBL:ENSP00000326948|REFSEQ:NP_036412|H-INV:HIT000274962|VEGA:OTTHUMP00000025795 Tax_Id=9606 Gene_Symbol=FTSJ1 Isoform 1 of Putative ribosomal RNA methyltransferase 1 [ipi.HUMAN.20110912.fasta]
  • Putative ribosomal RNA methyltransferase 1 GN=FTSJ1 [Doctor+uniprot-HUMAN-120911.fasta]
  • Tax_Id=9606 Gene_Symbol=FTSJ1 Isoform 1 of Putative ribosomal RNA methyltransferase 1 [human-ipi-270911-contam-BSA.fasta]
  • Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase OS=Homo sapiens GN=FTSJ1 PE=3 SV=1 [uniprot-human-031015-contam.fasta]
    • Organism: Homo sapiens
    Length: 329 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRTSKDKRD VYYRLAKENG WRARSAFKLL QLDKEFQLFQ GVTRAVDLCA APGSWSQVLS  60
   61 QKIGGQGSGH VVAVDLQAMA PLPGVVQIQG DITQLSTAKE IIQHFKGCPA DLVVCDGAPD 120
  121 VTGLHDVDEY MQAQLLLAAL NIATHVLKPG GCFVAKIFRG RDVTLLYSQL QVFFSSVLCA 180
  181 KPRSSRNSSI EAFAVCQGYD PPEGFIPDLS KPLLDHSYDP DFNQLDGPTR IIVPFVTCGD 240
  241 LSSYDSDRSY PLDLEGGSEY KYTPPTQPPI SPPYQEACTL KRKGQLAKEI RPQDCPISRV 300
  301 DTFPQPLAAP QCHTLLAPEM EDNEMSCSP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..202] PSI-BLAST 41.30103 RNA methyltransferase FtsJ
    2 View Details [203..329] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • methyltransferase activity
    		•  4.15445027778357 bayes_pls_golite062009
  • rRNA methyltransferase activity
    		•  4.09362182773099 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  4.07806017452628 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  4.07153733729662 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  3.92746815303714 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  3.39429041855776 bayes_pls_golite062009
  • RNA methyltransferase activity
    		•  3.07428840534971 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  2.99461585647365 bayes_pls_golite062009
  • transferase activity
    		•  2.926540904444 bayes_pls_golite062009
  • tRNA methyltransferase activity
    		•  2.5931020126592 bayes_pls_golite062009
  • protein-arginine N-methyltransferase activity
    		•  2.41876112831625 bayes_pls_golite062009
  • arginine N-methyltransferase activity
    		•  2.41876112831625 bayes_pls_golite062009
  • DNA-methyltransferase activity
    		•  2.18991764495147 bayes_pls_golite062009
  • histone-arginine N-methyltransferase activity
    		•  2.04296107639729 bayes_pls_golite062009
  • tRNA (cytosine)-methyltransferase activity
    		•  1.88889414729709 bayes_pls_golite062009
  • tRNA (cytosine-5-)-methyltransferase activity
    		•  1.88889414729709 bayes_pls_golite062009
  • rRNA (adenine) methyltransferase activity
    		•  1.83964463328968 bayes_pls_golite062009
  • rRNA (adenine-N6,N6-)-dimethyltransferase activity
    		•  1.75675289134467 bayes_pls_golite062009
  • protein-arginine omega-N monomethyltransferase activity
    		•  1.66871163498737 bayes_pls_golite062009
  • tRNA (adenine-N1-)-methyltransferase activity
    		•  1.29759910099835 bayes_pls_golite062009
  • tRNA (adenine)-methyltransferase activity
    		•  1.29759910099835 bayes_pls_golite062009
  • catalytic activity
    		•  1.25333584501255 bayes_pls_golite062009
  • histone methyltransferase activity (H4-R3 specific)
    		•  1.1103522853299 bayes_pls_golite062009
  • rRNA (guanine) methyltransferase activity
    		•  1.10713374933008 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.914549843668268 bayes_pls_golite062009
  • protein-arginine omega-N asymmetric methyltransferase activity
    		•  0.89325812193225 bayes_pls_golite062009
  • DNA binding
    		•  0.71058003448013 bayes_pls_golite062009
  • site-specific DNA-methyltransferase (adenine-specific) activity
    		•  0.703178429468566 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.698509190696763 bayes_pls_golite062009
  • RNA binding
    		•  0.417524996559564 bayes_pls_golite062009
  • binding
    		•  0.383237930789959 bayes_pls_golite062009
  • protein-arginine omega-N symmetric methyltransferase activity
    		•  0.364369105571521 bayes_pls_golite062009
  • O-methyltransferase activity
    		•  0.250946859465502 bayes_pls_golite062009
  • rRNA (guanine-N1-)-methyltransferase activity
    		•  0.234572322347698 bayes_pls_golite062009
  • tRNA (guanine) methyltransferase activity
    		•  0.203168546434167 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle