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Protein Overview: DCPS

General Information:
Name(s) found: DCPS [HGNC (HUGO)]
Description(s) found:
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  • gi|7661734|ref|NP_054745.1| mRNA decapping enzyme [Homo sapiens] [NCBI NR]
  • gi|4679016|gb|AAD26996.1| HSPC015 [Homo sapiens] [NCBI NR]
  • gi|30138167|gb|AAL77216.1| heat shock-like protein 1 [Homo sapiens] [NCBI NR]
  • gi|22038176|gb|AAM90310.1| scavenger mRNA decapping enzyme [Homo sapiens] [NCBI NR]
  • gi|21654924|gb|AAK91765.1| histidine triad protein member 5 [Homo sapiens] [NCBI NR]
  • gi|119588095|gb|EAW67691.1| decapping enzyme, scavenger [Homo sapiens] [NCBI NR]
  • gi|116241325|sp|Q96C86.2|DCPS_HUMAN RecName: Full=Scavenger mRNA-decapping enzyme DcpS; AltName: Full=DCS-1; AltName: Full=Hint-related 7meGMP-directed hydrolase; AltName: Full=Histidine triad protein member 5; Short=HINT-5 [NCBI NR]
  • decapping enzyme, scavenger [HGNC (HUGO)]
  • m7GpppX diphosphatase OS=Homo sapiens GN=DCPS PE=1 SV=2 [Swiss-Prot]
  • HSPC015 [hmr_yeast5_DM3-1_pombe.fasta]
  • mRNA decapping enzyme; histidine triad protein member 5; heat shock-like protein 1 [HMR_022704.fasta]
  • heat shock-like protein 1 [Homo sapiens]gi|7661734|ref|NP_054745.1| mRNA decapping enzyme [Homo sapiens]gi|22038176|gb|AAM90310.1| scavenger mRNA decapping enzyme [Homo sapiens]gi|21654924|gb|AAK91765.1| histidine triad protein member 5 [Homo sapiens] [nrdb_11152004_Chlamydomonas]
  • (NM_014026) histidine triad protein member 5 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • mRNA decapping enzyme [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • mRNA decapping enzyme; histidine triad protein member 5; heat shock-like protein 1 [Homo sapiens] [HumanGallus06162005.fasta]
  • Scavenger mRNA-decapping enzyme DcpS (DCS-1) (Hint-related 7meGMP-directed hydrolase) (Histidine triad protein member 5) (HINT-5) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • decapping enzyme, scavenger [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • heat shock-like protein 1 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • scavenger mRNA decapping enzyme [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • histidine triad protein member 5 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • HSPC015 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Scavenger mRNA decapping enzyme DcpS [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=DCPS Scavenger mRNA-decapping enzyme DcpS [human-ipi-250309-contam.fasta]
  • Scavenger mRNA decapping enzyme DcpS (DCS-1) (Hint-related 7meGMP-directed hydrolase) (Histidine triad protein member 5) (HINT-5) [nr-271106-contam.fasta]
  • IPI:IPI00335385.4|SWISS-PROT:Q96C86|TREMBL:Q53G42|ENSEMBL:ENSP00000263579|REFSEQ:NP_054745|H-INV:HIT000081314 Tax_Id=9606 Gene_Symbol=DCPS Scavenger mRNA-decapping enzyme DcpS [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=DCPS Scavenger mRNA-decapping enzyme DcpS ENSG00000110063 IPI00335385 [drosphohumanreversed.fasta]
  • scavenger mRNA-decapping enzyme DcpS [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Scavenger mRNA-decapping enzyme DcpS OS=Homo sapiens GN=DCPS PE=1 SV=2 [UniProtHuman070710.fasta]
  • Q96C86;Q8NHL8;Q9Y2S5; RecName: Full=Scavenger mRNA-decapping enzyme DcpS; AltName: Full=DCS-1; AltName: Full=Hint-related 7meGMP-directed hydrolase; AltName: Full=Histidine triad protein member 5; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Scavenger mRNA-decapping enzyme DcpS OS=Homo sapiens GN=DCPS [011711_HMR.fasta]
  • GeneSymbol=DCPS Synonyms=HINT-5|HSL1 scavenger mRNA-decapping enzyme DcpS [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00335385.4|SWISS-PROT:Q96C86|TREMBL:Q53G42|ENSEMBL:ENSP00000263579|REFSEQ:NP_054745|H-INV:HIT000081314|VEGA:OTTHUMP00000231113 Tax_Id=9606 Gene_Symbol=DCPS Scavenger mRNA-decapping enzyme DcpS [ipi.HUMAN.20110912.fasta]
  • m7GpppX diphosphatase GN=DCPS [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 337 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADAAPQLGK RKRELDVEEA HAASTEEKEA GVGNGTCAPV RLPFSGFRLQ KVLRESARDK  60
   61 IIFLHGKVNE ASGDGDGEDA VVILEKTPFQ VEQVAQLLTG SPELQLQFSN DIYSTYHLFP 120
  121 PRQLNDVKTT VVYPATEKHL QKYLRQDLRL IRETGDDYRN ITLPHLESQS LSIQWVYNIL 180
  181 DKKAEADRIV FENPDPSDGF VLIPDLKWNQ QQLDDLYLIA ICHRRGIRSL RDLTPEHLPL 240
  241 LRNILHQGQE AILQRYRMKG DHLRVYLHYL PSYYHLHVHF TALGFEAPGS GVERAHLLAE 300
  301 VIENLECDPR HYQQRTLTFA LRADDPLLKL LQEAQQS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..337] PSI-BLAST 136.0 Structure of human Dcps

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • m7G(5')pppN diphosphatase activity
    		•  11.4290795741181 bayes_pls_golite062009
  • RNA binding
    		•  2.65561768780165 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.24536295645879 bayes_pls_golite062009
  • binding
    		•  1.12315862086587 bayes_pls_golite062009
  • hydrolase activity
    		•  0.927269748430359 bayes_pls_golite062009
  • catalytic activity
    		•  0.096119422680995 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle