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View Structure Prediction Details

Protein: DCPS
Organism: Homo sapiens
Length: 337 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DCPS.

Description E-value Query
Range
Subject
Range
gi|62738483, gi|... - gi|62738483|pdb|1XML|A Chain A, Structure Of Human Dcps, gi|62738482|pdb|1XML|B Chain B, Structure O...
0.0 [1..337] [6..342]
DCPS_PIG - m7GpppX diphosphatase OS=Sus scrofa GN=DCPS PE=2 SV=1
0.0 [1..337] [1..337]
DCPS_BOVIN - m7GpppX diphosphatase OS=Bos taurus GN=DCPS PE=2 SV=1
0.0 [1..337] [1..337]
gi|73954893 - gi|73954893|ref|XP_851900.1| PREDICTED: similar to mRNA decapping enzyme [Canis familiaris]
0.0 [1..337] [29..362]
gi|52696230, gi|... - gi|52696230|pdb|1VLR|B Chain B, Crystal Structure Of Mrna Decapping Enzyme (Dcps) From Mus Musculus ...
0.0 [1..326] [13..337]

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Predicted Domain #1
Region A:
Residues: [1-337]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADAAPQLGK RKRELDVEEA HAASTEEKEA GVGNGTCAPV RLPFSGFRLQ KVLRESARDK  60
   61 IIFLHGKVNE ASGDGDGEDA VVILEKTPFQ VEQVAQLLTG SPELQLQFSN DIYSTYHLFP 120
  121 PRQLNDVKTT VVYPATEKHL QKYLRQDLRL IRETGDDYRN ITLPHLESQS LSIQWVYNIL 180
  181 DKKAEADRIV FENPDPSDGF VLIPDLKWNQ QQLDDLYLIA ICHRRGIRSL RDLTPEHLPL 240
  241 LRNILHQGQE AILQRYRMKG DHLRVYLHYL PSYYHLHVHF TALGFEAPGS GVERAHLLAE 300
  301 VIENLECDPR HYQQRTLTFA LRADDPLLKL LQEAQQS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 136.0
Match: 1xmlB
Description: Structure of human Dcps
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
m7G(5')pppN diphosphatase activity 11.4290795741181 bayes_pls_golite062009
RNA binding 2.65561768780165 bayes_pls_golite062009
nucleic acid binding 1.24536295645879 bayes_pls_golite062009
binding 1.12315862086587 bayes_pls_golite062009
hydrolase activity 0.927269748430359 bayes_pls_golite062009
catalytic activity 0.096119422680995 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle