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Protein Overview: POLR1D

General Information:
Name(s) found: POLR1D [HGNC (HUGO)]
Description(s) found:
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  • gi|7705740|ref|NP_057056.1| polymerase (RNA) I polypeptide D isoform 1 [Homo sapiens] [NCBI NR]
  • gi|55957689|emb|CAI16933.1| polymerase (RNA) I polypeptide D, 16kDa [Homo sapiens] [NCBI NR]
  • gi|4689136|gb|AAD27777.1|AF077044_1 RNA polymerase I 16 kDa subunit [Homo sapiens] [NCBI NR]
  • gi|12654143|gb|AAH00889.1| Polymerase (RNA) I polypeptide D, 16kDa [Homo sapiens] [NCBI NR]
  • gi|119628820|gb|EAX08415.1| hCG2020048, isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|11387119|sp|Q9Y2S0.1|RPAC2_HUMAN RecName: Full=DNA-directed RNA polymerases I and III subunit RPAC2; Short=RNA polymerases I and III subunit AC2; Short=DNA-directed RNA polymerase I subunit D; AltName: Full=DNA-directed RNA polymerase I 16 kDa polypept [NCBI NR]
  • polymerase (RNA) I polypeptide D, 16kDa [HGNC (HUGO)]
  • DNA-directed RNA polymerase I subunit D (EC 2.7.7.6) (DNA-directed RNA polymerase I 16 kDa polypeptide) (RPA16) - Homo sapiens (Human) [Swiss-Prot]
  • DNA-directed RNA polymerases I and III subunit RPAC2 OS=Homo sapiens GN=POLR1D PE=1 SV=1 [Swiss-Prot]
  • (Q9Y2S0) DNA-directed RNA polymerase I 16 kDa polypeptide (EC 2.7.7.6) (RPA16) [Swiss-Prot]
  • DNA-directed RNA polymerase I 16 kDa polypeptide [hmr_yeast5_DM3-1_pombe.fasta]
  • RNA polymerase I 16 kDa subunit [HMR_022704.fasta]
  • RNA polymerase I 16 kDa subunit [Homo sapiens]gi|12654143|gb|AAH00889.1| RNA polymerase I 16 kDa subunit [Homo sapiens]gi|4689136|gb|AAD27777.1| RNA polymerase I 16 kDa subunit [Homo sapiens]gi|11387119|sp|Q9Y2S0|RPA9_HUMAN DNA-directed RNA polymerase [nrdb_11152004_Chlamydomonas]
  • DNA-directed RNA polymerase I 16 kDa polypeptide (RPA16) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 DNA-directed RNA polymerase I subunit D [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_015972) RNA polymerase I 16 kDa subunit [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • polymerase (RNA) I polypeptide D isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 DNA-directed RNA polymerase I 16 kDa polypeptide [EBI-IPI_human_3.12_11-03-2005_con_reversed.fasta]
  • RNA polymerase I 16 kDa subunit [Homo sapiens] [HumanGallus06162005.fasta]
  • DNA-directed RNA polymerases I and III subunit RPAC2 (RNA polymerases I and III subunit AC2) (DNA-directed RNA polymerase I subunit D) (DNA-directed RNA polymerase I 16 kDa polypeptide) (RPA16) (RPC16) (hRPA19) (AC19) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • polymerase (RNA) I polypeptide D, 16kDa [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • hCG2020048, isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Polymerase (RNA) I polypeptide D, 16kDa [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 DNA-DIRECTED RNA POLYMERASE I 16 KDA POLYPEPTIDE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • RecName: Full=DNA-directed RNA polymerases I and III subunit RPAC2; Short=RNA polymerases I and III subunit AC2; Short=DNA-directed RNA polymerase I subunit D; AltName: Full=DNA-directed RNA polymerase I 16 kDa polypeptide; Short=RPA16; AltName: Full=RPC1 [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=POLR1D Isoform 1 of DNA-directed RNA polymerases I and III subunit RPAC2 [human-ipi-250309-contam.fasta]
  • Polymerase (RNA) I polypeptide C [Homo sapiens] [nr-271106-contam.fasta]
  • DNA-directed RNA polymerase I subunit D (DNA-directed RNA polymerase I 16 kDa polypeptide) (RPA16) [nr-271106-contam.fasta]
  • IPI:IPI00032439.1|SWISS-PROT:Q9Y2S0-1|ENSEMBL:ENSP00000302478;ENSP00000382603|REFSEQ:NP_057056|H-INV:HIT000286852|VEGA:OTTHUMP00000018171 Tax_Id=9606 Gene_Symbol=POLR1D Isoform 1 of DNA-directed RNA polymerases I and III subunit RPAC2 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=POLR1D DNA-directed RNA polymerases I and III subunit RPAC2 ENSG00000186184 IPI00032439 IPI00643892 [drosphohumanreversed.fasta]
  • Tax_Id=9606 Gene_Symbol=POLR1D DNA-directed RNA polymerases I and III subunit RPAC2 [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • DNA-directed RNA polymerases I and III subunit RPAC2 isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Q9Y2S0;Q5TBX2;Q96BR3; RecName: Full=DNA-directed RNA polymerases I and III subunit RPAC2; AltName: Full=DNA-directed RNA polymerase I subunit D; AltName: Full=RNA polymerase I 16 kDa subunit; AltName: Full=RPC16; AltName: Full=hRPA19; AltName: Full=AC19; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Isoform 1 of DNA-directed RNA polymerases I and III subunit RPAC2 OS=Homo sapiens GN=POLR1D [011711_HMR.fasta]
  • GeneSymbol=POLR1D Synonyms=AC19|FLJ20616|MGC9850|POLR1C|RPA16|RPA9|RPAC2|RPC16|RPO1-3|TCS2 DNA-directed RNA polymerases I and III subunit RPAC2 isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • DNA-directed RNA polymerases I and III subunit RPAC2 GN=POLR1D [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 133 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEDQELERK ISGLKTSMAE GERKTALEMV QAAGTDRHCV TFVLHEEDHT LGNSLRYMIM  60
   61 KNPEVEFCGY TTTHPSESKI NLRIQTRGTL PAVEPFQRGL NELMNVCQHV LDKFEASIKD 120
  121 YKDQKASRNE STF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..133] PSI-BLAST 26.154902 RPB11

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • DNA-directed RNA polymerase activity
    		•  8.95763217796707 bayes_pls_golite062009
  • RNA polymerase activity
    		•  8.95763217796707 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  6.40098308297479 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  4.33401073482737 bayes_pls_golite062009
  • transferase activity
    		•  3.84777794959854 bayes_pls_golite062009
  • binding
    		•  2.52848545896742 bayes_pls_golite062009
  • DNA binding
    		•  1.9558633290744 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.91068858292286 bayes_pls_golite062009
  • catalytic activity
    		•  0.902495165806215 bayes_pls_golite062009
  • protein binding
    		•  0.812922434823933 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle