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View Structure Prediction Details

Protein: POLR1D
Organism: Homo sapiens
Length: 133 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for POLR1D.

Description E-value Query
Range		 Subject
Range
gi|73957788 - gi|73957788|ref|XP_546937.2| PREDICTED: similar to RAS p21 protein activator 4 [Canis familiaris]
 6.0E-38 [9..123] [994..1105]
gi|109121411 - gi|109121411|ref|XP_001110871.1| PREDICTED: polymerase (RNA) I polypeptide D, 16kDa [Macaca mulatta]
 1.0E-37 [1..133] [1..133]
RPAC2_BOVIN - DNA-directed RNA polymerases I and III subunit RPAC2 OS=Bos taurus GN=POLR1D PE=2 SV=1
 3.0E-37 [1..133] [1..133]
RPAC2_MOUSE - DNA-directed RNA polymerases I and III subunit RPAC2 OS=Mus musculus GN=Polr1d PE=1 SV=1
 7.0E-37 [1..133] [1..133]
gi|67540776, gi|... - gi|67540776|ref|XP_664162.1| hypothetical protein AN6558.2 [Aspergillus nidulans FGSC A4], ref|XP_41...
 3.0E-34 [2..131] [8..137]
gi|40226460 - gi|40226460|gb|AAH17341.2| POLR2J4 protein [Homo sapiens]
 1.0E-33 [9..115] [18..122]

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Predicted Domain #1
Region A:
Residues: [1-133] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEDQELERK ISGLKTSMAE GERKTALEMV QAAGTDRHCV TFVLHEEDHT LGNSLRYMIM  60
   61 KNPEVEFCGY TTTHPSESKI NLRIQTRGTL PAVEPFQRGL NELMNVCQHV LDKFEASIKD 120
  121 YKDQKASRNE STF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.154902
Match: 1i3qK
Description: RPB11
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA-directed RNA polymerase activity 8.95763217796707 bayes_pls_golite062009
RNA polymerase activity 8.95763217796707 bayes_pls_golite062009
nucleotidyltransferase activity 6.40098308297479 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 4.33401073482737 bayes_pls_golite062009
transferase activity 3.84777794959854 bayes_pls_golite062009
binding 2.52848545896742 bayes_pls_golite062009
DNA binding 1.9558633290744 bayes_pls_golite062009
nucleic acid binding 1.91068858292286 bayes_pls_golite062009
catalytic activity 0.902495165806215 bayes_pls_golite062009
protein binding 0.812922434823933 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle