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Protein Overview: NCKAP1

General Information:
Name(s) found: NCKAP1 [HGNC (HUGO)]
Description(s) found:
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  • gi|7305303|ref|NP_038464.1| NCK-associated protein 1 isoform 1 [Homo sapiens] [NCBI NR]
  • gi|4760464|dbj|BAA77295.1| Nck-associated protein 1 (Nap1) [Homo sapiens] [NCBI NR]
  • gi|30582905|gb|AAP35681.1| NCK-associated protein 1 [Homo sapiens] [NCBI NR]
  • gi|15929137|gb|AAH15025.1| NCK-associated protein 1 [Homo sapiens] [NCBI NR]
  • gi|158259289|dbj|BAF85603.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|12643947|sp|Q9Y2A7.1|NCKP1_HUMAN RecName: Full=Nck-associated protein 1; Short=NAP 1; AltName: Full=p125Nap1; AltName: Full=Membrane-associated protein HEM-2 [NCBI NR]
  • NCK-associated protein 1 [HGNC (HUGO)]
  • (Q9Y2A7) Nck-associated protein 1 (NAP 1) (p125Nap1) (Membrane-associated protein HEM-2) [Swiss-Prot]
  • Nck-associated protein 1 OS=Homo sapiens GN=NCKAP1 PE=1 SV=1 [Swiss-Prot]
  • Nck-associated protein 1 [hmr_yeast5_DM3-1_pombe.fasta]
  • NCK-associated protein 1 isoform 1 [HMR_022704.fasta]
  • NCK-associated protein 1 [Homo sapiens]gi|7305303|ref|NP_038464.1| NCK-associated protein 1 isoform 1 [Homo sapiens]gi|15929137|gb|AAH15025.1| NCK-associated protein 1, isoform 1 [Homo sapiens]gi|12643947|sp|Q9Y2A7|NCP1_HUMAN Nck-associated protein 1 ( [nrdb_11152004_Chlamydomonas]
  • Nck-associated protein 1 (NAP 1) (p125Nap1) (Membrane-associated protein HEM-2) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Nck-associated protein 1 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_013436) NCK-associated protein 1 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • NCK-associated protein 1 isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • NCK-associated protein 1 [Homo sapiens] [human-NCBI-042104-rand.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Nck-associated protein 1 (Nap1) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 NCK-ASSOCIATED PROTEIN 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=NCKAP1 Isoform 1 of Nck-associated protein 1 [human-ipi-250309-contam.fasta]
  • IPI:IPI00031982.1|SWISS-PROT:Q9Y2A7-1|TREMBL:B3KMK7|ENSEMBL:ENSP00000355348|REFSEQ:NP_038464|H-INV:HIT000036967|VEGA:OTTHUMP00000163460 Tax_Id=9606 Gene_Symbol=NCKAP1 Isoform 1 of Nck-associated protein 1 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=NCKAP1 Nck-associated protein 1 [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • nck-associated protein 1 isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Q9Y2A7;O60329;Q53QN5;Q53S94;Q53Y35; RecName: Full=Nck-associated protein 1; AltName: Full=p125Nap1; AltName: Full=Membrane-associated protein HEM-2; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Isoform 1 of Nck-associated protein 1 OS=Homo sapiens GN=NCKAP1 [011711_HMR.fasta]
  • Nck-associated protein 1 n=36 Tax=Euteleostomi RepID=NCKP1_HUMAN [UniProt_Xenopus_laevis_01-01-2011_reversed.fasta]
  • GeneSymbol=NCKAP1 Synonyms=FLJ11291|HEM2|KIAA0587|MGC8981|NAP1|NAP125 nck-associated protein 1 isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • Nck-associated protein 1 GN=NCKAP1 [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 1128 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRSVLQPSQ QKLAEKLTIL NDRGVGMLTR LYNIKKACGD PKAKPSYLID KNLESAVKFI  60
   61 VRKFPAVETR NNNQQLAQLQ KEKSEILKNL ALYYFTFVDV MEFKDHVCEL LNTIDVCQVF 120
  121 FDITVNFDLT KNYLDLIITY TTLMILLSRI EERKAIIGLY NYAHEMTHGA SDREYPRLGQ 180
  181 MIVDYENPLK KMMEEFVPHS KSLSDALISL QMVYPRRNLS ADQWRNAQLL SLISAPSTML 240
  241 NPAQSDTMPC EYLSLDAMEK WIIFGFILCH GILNTDATAL NLWKLALQSS SCLSLFRDEV 300
  301 FHIHKAAEDL FVNIRGYNKR INDIRECKEA AVSHAGSMHR ERRKFLRSAL KELATVLSDQ 360
  361 PGLLGPKALF VFMALSFARD EIIWLLRHAD NMPKKSADDF IDKHIAELIF YMEELRAHVR 420
  421 KYGPVMQRYY VQYLSGFDAV VLNELVQNLS VCPEDESIIM SSFVNTMTSL SVKQVEDGEV 480
  481 FDFRGMRLDW FRLQAYTSVS KASLGLADHR ELGKMMNTII FHTKMVDSLV EMLVETSDLS 540
  541 IFCFYSRAFE KMFQQCLELP SQSRYSIAFP LLCTHFMSCT HELCPEERHH IGDRSLSLCN 600
  601 MFLDEMAKQA RNLITDICTE QCTLSDQLLP KHCAKTISQA VNKKSKKQTG KKGEPEREKP 660
  661 GVESMRKNRL VVTNLDKLHT ALSELCFSIN YVPNMVVWEH TFTPREYLTS HLEIRFTKSI 720
  721 VGMTMYNQAT QEIAKPSELL TSVRAYMTVL QSIENYVQID ITRVFNNVLL QQTQHLDSHG 780
  781 EPTITSLYTN WYLETLLRQV SNGHIAYFPA MKAFVNLPTE NELTFNAEEY SDISEMRSLS 840
  841 ELLGPYGMKF LSESLMWHIS SQVAELKKLV VENVDVLTQM RTSFDKPDQM AALFKRLSSV 900
  901 DSVLKRMTII GVILSFRSLA QEALRDVLSY HIPFLVSSIE DFKDHIPRET DMKVAMNVYE 960
  961 LSSAAGLPCE IDPALVVALS SQKSENISPE EEYKIACLLM VFVAVSLPTL ASNVMSQYSP1020
 1021 AIEGHCNNIH CLAKAINQIA AALFTIHKGS IEDRLKEFLA LASSSLLKIG QETDKTTTRN1080
 1081 RESVYLLLDM IVQESPFLTM DLLESCFPYV LLRNAYHAVY KQSVTSSA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run gi|14317902, gi|... No Comments Cheeseman, I.M., et al. (2004)
    View Run MIS12 No Comments Cheeseman, I.M., et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..244] deduced N/A No confident structure predictions are available.
    2 View Details [245..393] deduced N/A No confident structure predictions are available.
    3 View Details [394..508] deduced N/A Confident ab initio structure predictions are available.
    4 View Details [509..653] deduced N/A Confident ab initio structure predictions are available.
    5 View Details [654..817] deduced N/A No confident structure predictions are available.
    6 View Details [818..933] deduced N/A Confident ab initio structure predictions are available.
    7 View Details [934..1128] MSA 1.017933 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.83

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle