Protein Overview: CENPB

General Information:
Name(s) found:	CENPB [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|31753174\|gb\|AAH53847.1\| Centromere protein B, 80kDa [Homo sapiens] [NCBI NR] gi\|29861\|emb\|CAA38879.1\| centromere autoantigen B (CENP-B) [Homo sapiens] [NCBI NR] gi\|21735415\|ref\|NP_001801.1\| centromere protein B [Homo sapiens] [NCBI NR] gi\|116109\|sp\|P07199.2\|CENPB_HUMAN RecName: Full=Major centromere autoantigen B; Short=Centromere protein B; AltName: Full=CENP-B [NCBI NR] gi\|11493369\|emb\|CAC17547.1\| centromere protein B, 80kDa [Homo sapiens] [NCBI NR] pir\|\|S18735 centromere protein B - human [NCBI NR] centromere protein B, 80kDa [HGNC (HUGO)] Major centromere autoantigen B OS=Homo sapiens GN=CENPB PE=1 SV=2 [Swiss-Prot] (P07199) Major centromere autoantigen B (Centromere protein B) (CENP-B) [Swiss-Prot] Major centromere autoantigen B [hmr_yeast5_DM3-1_pombe.fasta] centromere protein B; centromere protein B (80kD); centromere autoantigen B [HMR_022704.fasta] centromere protein B [Homo sapiens]gi\|31753174\|gb\|AAH53847.1\| Centromere protein B [Homo sapiens]gi\|11493369\|emb\|CAC17547.1\| dJ1009E24.5 (Centromere protein B (80KDa)) [Homo sapiens]gi\|105603\|pir\|\|S18735 centromere protein B - humangi\|29861\|emb\|CAA388 [nrdb_11152004_Chlamydomonas] Major centromere autoantigen B (Centromere protein B) (CENP-B) [Yateslab_human_na_07-28-2006_reversed.fasta] Tax_Id=9606 Major centromere autoantigen B [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta] (NM_001810) centromere protein B (80kD); Centromeric protein B [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] centromere protein B [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta] centromere protein B; centromere protein B (80kD); centromere autoantigen B [Homo sapiens] [HumanGallus06162005.fasta] centromere protein B, 80kDa [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] centromere autoantigen B (CENP-B) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Centromere protein B, 80kDa [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tax_Id=9606 MAJOR CENTROMERE AUTOANTIGEN B [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=9606 Gene_Symbol=CENPB Major centromere autoantigen B [human-ipi-250309-contam.fasta] CENPB [Homo sapiens] [nr-271106-contam.fasta] IPI:IPI00010388.1\|SWISS-PROT:P07199\|TREMBL:Q71VN3;Q71VN4;Q96EI4\|ENSEMBL:ENSP00000369075\|REFSEQ:NP_001801\|H-INV:HIT000053988\|VEGA:OTTHUMP00000030132 Tax_Id=9606 Gene_Symbol=CENPB Major centromere autoantigen B [ipi.HUMAN.fasta.20090807] [human_BMb_040710_contam.fasta] Tax_Id=9606 Gene_Symbol=CENPB Major centromere autoantigen B ENSG00000125817 IPI00010388 [drosphohumanreversed.fasta] major centromere autoantigen B [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] P07199; RecName: Full=Major centromere autoantigen B; AltName: Full=Centromere protein B; [UniProt_Human_2010_06_06-01-2010_reversed.fasta] Major centromere autoantigen B OS=Homo sapiens GN=CENPB [011711_HMR.fasta] GeneSymbol=CENPB Synonyms=- major centromere autoantigen B [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] IPI:IPI00010388.1\|SWISS-PROT:P07199\|TREMBL:Q71VN4\|ENSEMBL:ENSP00000369075\|REFSEQ:NP_001801\|H-INV:HIT000053988\|VEGA:OTTHUMP00000030132 Tax_Id=9606 Gene_Symbol=CENPB Major centromere autoantigen B [ipi.HUMAN.20110912.fasta] Major centromere autoantigen B GN=CENPB [Doctor+uniprot-HUMAN-120911.fasta]
Organism:	Homo sapiens
Length:	599 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGPKRRQLTF REKSRIIQEV EENPDLRKGE IARRFNIPPS TLSTILKNKR AILASERKYG  60
   61 VASTCRKTNK LSPYDKLEGL LIAWFQQIRA AGLPVKGIIL KEKALRIAEE LGMDDFTASN 120
  121 GWLDRFRRRH GVVSCSGVAR ARARNAAPRT PAAPASPAAV PSEGSGGSTT GWRAREEQPP 180
  181 SVAEGYASQD VFSATETSLW YDFLPDQAAG LCGGDGRPRQ ATQRLSVLLC ANADGSEKLP 240
  241 PLVAGKSAKP RAGQAGLPCD YTANSKGGVT TQALAKYLKA LDTRMAAESR RVLLLAGRLA 300
  301 AQSLDTSGLR HVQLAFFPPG TVHPLERGVV QQVKGHYRQA MLLKAMAALE GQDPSGLQLG 360
  361 LTEALHFVAA AWQAVEPSDI AACFREAGFG GGPNATITTS LKSEGEEEEE EEEEEEEEEG 420
  421 EGEEEEEEGE EEEEEGGEGE ELGEEEEVEE EGDVDSDEEE EEDEESSSEG LEAEDWAQGV 480
  481 VEAGGSFGAY GAQEEAQCPT LHFLEGGEDS DSDSEEEDDE EEDDEDEDDD DDEEDGDEVP 540
  541 VPSFGEAMAY FAMVKRYLTS FPIDDRVQSH ILHLEHDLVH VTRKNHARQA GVRGLGHQS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..177]	PSI-BLAST	30.0	DNA-binding domain of centromere binding protein B (CENP-B)
2	View Details	[178..390]	Pfam	69.744727	No description for PF03184.6 was found. No confident structure predictions are available.
3	View Details	[391..525]	MSA	1.200996	View MSA. No confident structure predictions are available.
4	View Details	[526..599]	PSI-BLAST	7.045757	Crystal structure of the dimerization domain of human CENP-B

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: CENPB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: