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Protein Overview: NT5E

General Information:
Name(s) found: NT5E [HGNC (HUGO)]
Description(s) found:
Found 31 descriptions.
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  • 5'-nucleotidase, ecto (CD73) [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 574 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCPRAARAPA TLLLALGAVL WPAAGAWELT ILHTNDVHSR LEQTSEDSSK CVNASRCMGG  60
   61 VARLFTKVQQ IRRAEPNVLL LDAGDQYQGT IWFTVYKGAE VAHFMNALRY DAMALGNHEF 120
  121 DNGVEGLIEP LLKEAKFPIL SANIKAKGPL ASQISGLYLP YKVLPVGDEV VGIVGYTSKE 180
  181 TPFLSNPGTN LVFEDEITAL QPEVDKLKTL NVNKIIALGH SGFEMDKLIA QKVRGVDVVV 240
  241 GGHSNTFLYT GNPPSKEVPA GKYPFIVTSD DGRKVPVVQA YAFGKYLGYL KIEFDERGNV 300
  301 ISSHGNPILL NSSIPEDPSI KADINKWRIK LDNYSTQELG KTIVYLDGSS QSCRFRECNM 360
  361 GNLICDAMIN NNLRHTDEMF WNHVSMCILN GGGIRSPIDE RNNGTITWEN LAAVLPFGGT 420
  421 FDLVQLKGST LKKAFEHSVH RYGQSTGEFL QVGGIHVVYD LSRKPGDRVV KLDVLCTKCR 480
  481 VPSYDPLKMD EVYKVILPNF LANGGDGFQM IKDELLRHDS GDQDINVVST YISKMKVIYP 540
  541 AVEGRIKFST GSHCHGSFSL IFLSLWAVIF VLYQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..574] PSI-BLAST 109.0 5'-NUCLEOTIDASE FROM E. COLI

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphoprotein phosphatase activity
    		•  6.90309911517124 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  6.76617976580319 bayes_pls_golite062009
  • phosphatase activity
    		•  6.28072946025083 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  5.93537144836081 bayes_pls_golite062009
  • protein serine/threonine phosphatase activity
    		•  5.11265802430394 bayes_pls_golite062009
  • hydrolase activity
    		•  2.06280293513737 bayes_pls_golite062009
  • catalytic activity
    		•  1.39852585255405 bayes_pls_golite062009
  • binding
    		•  0.607014751804583 bayes_pls_golite062009
  • calcium-dependent protein serine/threonine phosphatase activity
    		•  0.598330833036731 bayes_pls_golite062009
  • protein kinase activity
    		•  0.55395641922978 bayes_pls_golite062009
  • signal transducer activity
    		•  0.541715460439478 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.541715460439478 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.395006104431866 bayes_pls_golite062009
  • kinase activity
    		•  0.366390322110727 bayes_pls_golite062009
  • protein binding
    		•  0.184079020957384 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.39246790349923E-4 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle