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Protein Overview: CLN3

General Information:
Name(s) found: CLN3 [HGNC (HUGO)]
Description(s) found:
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  • gi|5801861|gb|AAD51493.1|AF077971_1 CLN3 protein [Homo sapiens] [NCBI NR]
  • gi|5801843|gb|AAD51484.1|AF077962_1 CLN3 protein [Homo sapiens] [NCBI NR]
  • gi|5801841|gb|AAD51483.1|AF077961_1 CLN3 protein [Homo sapiens] [NCBI NR]
  • gi|5801837|gb|AAD51481.1|AF077959_1 CLN3 protein [Homo sapiens] [NCBI NR]
  • gi|5801835|gb|AAD51480.1|AF077958_1 CLN3 protein [Homo sapiens] [NCBI NR]
  • gi|5801833|gb|AAD51479.1|AF077957_1 CLN3 protein [Homo sapiens] [NCBI NR]
  • gi|5801831|gb|AAD51478.1|AF077956_1 CLN3 protein [Homo sapiens] [NCBI NR]
  • gi|5730394|gb|AAD48543.1|AF078169_1 CLN3 protein [Homo sapiens] [NCBI NR]
  • gi|4502889|ref|NP_000077.1| ceroid-lipofuscinosis, neuronal 3 [Homo sapiens] [NCBI NR]
  • gi|4102729|gb|AAD01555.1| CLN3 protein [Homo sapiens] [NCBI NR]
  • gi|3337387|gb|AAC27430.1| CLN [Homo sapiens] [NCBI NR]
  • gi|2947055|gb|AAC05337.1| CLN3 [Homo sapiens] [NCBI NR]
  • gi|2498243|sp|Q13286.1|CLN3_HUMAN RecName: Full=Battenin; AltName: Full=Protein CLN3; AltName: Full=Batten disease protein [NCBI NR]
  • gi|1834482|emb|CAA68148.1| CLN3 protein [Homo sapiens] [NCBI NR]
  • gi|1583579|prf||2121264A CLN3 gene [NCBI NR]
  • pir||A57219 Batten disease-related protein CLN3 - human [NCBI NR]
  • gi|13325228|gb|AAH04433.1| Ceroid-lipofuscinosis, neuronal 3 [Homo sapiens] [NCBI NR]
  • gi|12803177|gb|AAH02394.1| Ceroid-lipofuscinosis, neuronal 3 [Homo sapiens] [NCBI NR]
  • gi|119572683|gb|EAW52298.1| ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease), isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119572669|gb|EAW52284.1| ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease), isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119572666|gb|EAW52281.1| ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease), isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|109698601|ref|NP_001035897.1| ceroid-lipofuscinosis, neuronal 3 [Homo sapiens] [NCBI NR]
  • gi|1039423|gb|AAB51075.1| CLN3 protein [Homo sapiens] [NCBI NR]
  • ceroid-lipofuscinosis, neuronal 3 [HGNC (HUGO)]
  • Battenin OS=Homo sapiens GN=CLN3 PE=1 SV=1 [Swiss-Prot]
  • Splice isoform 1 of Q13286 [hmr_yeast5_DM3-1_pombe.fasta]
  • Batten disease protein CLN3 [HMR_022704.fasta]
  • CLN3 protein; battenin [071204_hmrz_cont.fasta]
  • CLN3 protein [Homo sapiens]gi|13325228|gb|AAH04433.1| CLN3 protein [Homo sapiens]gi|4502889|ref|NP_000077.1| CLN3 protein [Homo sapiens]gi|2947055|gb|AAC05337.1| CLN3 [Homo sapiens]gi|3337387|gb|AAC27430.1| CLN [Homo sapiens]gi|1039423|gb|AAB51075.1| [nrdb_11152004_Chlamydomonas]
  • CLN3 protein (Battenin) (Batten disease protein) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Splice Isoform 1 of Protein CLN3 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_000086) Batten disease protein CLN3 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • ceroid-lipofuscinosis, neuronal 3 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 Splice Isoform 1 of CLN3 protein [EBI-IPI_human_3.04_03-07-2005_reverse.fasta]
  • CLN3 protein; battenin [Homo sapiens] [HumanGallus06162005.fasta]
  • CLN3 protein [Homo sapiens] [human-contam-plus-rand.fasta]
  • Batten disease protein CLN3 [Homo sapiens] [human-NCBI-042104-rand.fasta]
  • Ceroid-lipofuscinosis, neuronal 3 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Battenin (Protein CLN3) (Batten disease protein) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease), isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • CLN [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • CLN3 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • CLN3 gene [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) [Homo sapiens] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=9606 Isoform 1 of Battenin [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 SPLICE ISOFORM 1 OF CLN3 PROTEIN [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=CLN3 Isoform 1 of Battenin [human-ipi-250309-contam.fasta]
  • Protein CLN3 (Battenin) (Batten disease protein) [nr-271106-contam.fasta]
  • IPI:IPI00012448.1|SWISS-PROT:Q13286-1|TREMBL:B2R7J1;B4DFF3;Q549S9|ENSEMBL:ENSP00000353073;ENSP00000353116|REFSEQ:NP_000077;NP_001035897|H-INV:HIT000030857|VEGA:OTTHUMP00000080343;OTTHUMP00000080344;OTTHUMP00000122517 Tax_Id=9606 Gene_Symbol=CLN3 Isoform 1 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=CLN3 Isoform 1 of Battenin ENSG00000188603 IPI00383669 IPI00217836 IPI00217835 IPI00217838 IPI00642284 IPI00639963 IPI00383568 IPI00383566 IPI00012448 IPI00644378 IPI00186092 IPI00028312 IPI00010905 IPI00010906 IPI00217837 IPI00640605 IPI00384849 IPI00719205 IPI00384850 [drosphohumanreversed.fasta]
  • battenin [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Q13286;O00668;Q9UP09;Q9UP11;Q9UP12;Q9UP13;Q9UP14; RecName: Full=Battenin; AltName: Full=Protein CLN3; AltName: Full=Batten disease protein; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Isoform 1 of Battenin OS=Homo sapiens GN=CLN3 [011711_HMR.fasta]
  • IPI:IPI00012448.1|SWISS-PROT:Q13286-1|TREMBL:B2R7J1;B4DFF3;Q549S9|ENSEMBL:ENSP00000353073;ENSP00000353116|REFSEQ:NP_000077;NP_001035897|H-INV:HIT000030857|VEGA:OTTHUMP00000080343;OTTHUMP00000080344;OTTHUMP00000122517 Tax_Id=9606 Gene_Symbol=CLN3 Isoform 1 of Battenin [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=CLN3 Synonyms=BTS|JNCL|MGC102840 battenin [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00012448.1|SWISS-PROT:Q13286-1|TREMBL:B2R7J1;O95085;Q549S9|ENSEMBL:ENSP00000353073;ENSP00000353116|REFSEQ:NP_000077;NP_001035897|H-INV:HIT000030857|VEGA:OTTHUMP00000122517 Tax_Id=9606 Gene_Symbol=CLN3 Isoform 1 of Battenin [ipi.HUMAN.20110912.fasta]
  • Battenin GN=CLN3 [Doctor+uniprot-HUMAN-120911.fasta]
  • Battenin OS=Homo sapiens GN=CLN3 PE=3 SV=1 [uniprot-human-031015-contam.fasta]
    • Organism: Homo sapiens
    Length: 438 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGGCAGSRRR FSDSEGEETV PEPRLPLLDH QGAHWKNAVG FWLLGLCNNF SYVVMLSAAH  60
   61 DILSHKRTSG NQSHVDPGPT PIPHNSSSRF DCNSVSTAAV LLADILPTLV IKLLAPLGLH 120
  121 LLPYSPRVLV SGICAAGSFV LVAFSHSVGT SLCGVVFASI SSGLGEVTFL SLTAFYPRAV 180
  181 ISWWSSGTGG AGLLGALSYL GLTQAGLSPQ QTLLSMLGIP ALLLASYFLL LTSPEAQDPG 240
  241 GEEEAESAAR QPLIRTEAPE SKPGSSSSLS LRERWTVFKG LLWYIVPLVV VYFAEYFINQ 300
  301 GLFELLFFWN TSLSHAQQYR WYQMLYQAGV FASRSSLRCC RIRFTWALAL LQCLNLVFLL 360
  361 ADVWFGFLPS IYLVFLIILY EGLLGGAAYV NTFHNIALET SDEHREFAMA ATCISDTLGI 420
  421 SLSGLLALPL HDFLCQLS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..438] FFAS03 1.83 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transporter activity
    		•  3.82096685159505 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.34396155292818 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.32643461660963 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.2506965512085 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  2.05049771748124 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.02370427376594 bayes_pls_golite062009
  • binding
    		•  1.9065830290222 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.62538016506437 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.46819549608723 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  0.869150152038001 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.339747214378126 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.339747214378126 bayes_pls_golite062009
  • symporter activity
    		•  0.327558013224678 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.327558013224678 bayes_pls_golite062009
  • hexose phosphate transmembrane transporter activity
    		•  0.273403673499648 bayes_pls_golite062009
  • glucose-6-phosphate transmembrane transporter activity
    		•  0.273403673499648 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.222664452597504 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle